Functional compatibility between isoform α and β of type II DNA topoisomerase

DNA topoisomerase II (topo II) plays a crucial role in controlling the conformation of both DNA and whole chromosomes. This activity is essential for several cellular events such as DNA replication, transcription, chromosome condensation and segregation. In mammals, two genes code for isoforms of to...

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Bibliografiska uppgifter
Huvudupphovsmän: Ayako Sakaguchi, Akihiko Kikuchi
Materialtyp: Artigo
Språk:engelska
Publicerad: 2004
Länkar:https://doi.org/10.1242/jcs.00977
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