Functional compatibility between isoform α and β of type II DNA topoisomerase

Functional compatibility between isoform α and β of type II DNA topoisomerase

DNA topoisomerase II (topo II) plays a crucial role in controlling the conformation of both DNA and whole chromosomes. This activity is essential for several cellular events such as DNA replication, transcription, chromosome condensation and segregation. In mammals, two genes code for isoforms of to...

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Autori principali:	Ayako Sakaguchi, Akihiko Kikuchi
Natura:	Artigo
Lingua:	inglese
Pubblicazione:	2004
Accesso online:	https://doi.org/10.1242/jcs.00977
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