Functional compatibility between isoform α and β of type II DNA topoisomerase
DNA topoisomerase II (topo II) plays a crucial role in controlling the conformation of both DNA and whole chromosomes. This activity is essential for several cellular events such as DNA replication, transcription, chromosome condensation and segregation. In mammals, two genes code for isoforms of to...
Sábháilte in:
Príomhchruthaitheoirí: | Ayako Sakaguchi, Akihiko Kikuchi |
---|---|
Formáid: | Artigo |
Teanga: | Béarla |
Foilsithe / Cruthaithe: |
2004
|
Rochtain ar líne: | https://doi.org/10.1242/jcs.00977 |
Clibeanna: |
Cuir clib leis
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
|
Míreanna comhchosúla
Míreanna comhchosúla
-
Involvement of DNA Topoisomerase IIβ in Neuronal Differentiation
de réir: Ken‐Ichiro Tsutsui, et al.
Foilsithe / Cruthaithe: (2001) -
The distribution and expression of the two isoforms of DNA topoisomerase II in normal and neoplastic human tissues
de réir: Helen Turley, et al.
Foilsithe / Cruthaithe: (1997) -
The α4 residues of human DNA topoisomerase IIα function in enzymatic activity and anticancer drug sensitivity
de réir: Suda, Namiko, et al.
Foilsithe / Cruthaithe: (2004) -
C-Terminal regions of topoisomerase IIα and IIβ determine isoform-specific functioning of the enzymes in vivo
de réir: Linka, René M., et al.
Foilsithe / Cruthaithe: (2007) -
Essential Mitotic Functions of DNA Topoisomerase IIα Are Not Adopted by Topoisomerase IIβ in Human H69 Cells
de réir: Pernille Grue, et al.
Foilsithe / Cruthaithe: (1998)