Functional compatibility between isoform α and β of type II DNA topoisomerase
DNA topoisomerase II (topo II) plays a crucial role in controlling the conformation of both DNA and whole chromosomes. This activity is essential for several cellular events such as DNA replication, transcription, chromosome condensation and segregation. In mammals, two genes code for isoforms of to...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | English |
| Published: |
2004
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| Online Access: | https://doi.org/10.1242/jcs.00977 |
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