Functional compatibility between isoform α and β of type II DNA topoisomerase
DNA topoisomerase II (topo II) plays a crucial role in controlling the conformation of both DNA and whole chromosomes. This activity is essential for several cellular events such as DNA replication, transcription, chromosome condensation and segregation. In mammals, two genes code for isoforms of to...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | Ayako Sakaguchi, Akihiko Kikuchi |
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Μορφή: | Artigo |
Γλώσσα: | Αγγλικά |
Έκδοση: |
2004
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Διαθέσιμο Online: | https://doi.org/10.1242/jcs.00977 |
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C-Terminal regions of topoisomerase IIα and IIβ determine isoform-specific functioning of the enzymes in vivo
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Έκδοση: (2007) -
Essential Mitotic Functions of DNA Topoisomerase IIα Are Not Adopted by Topoisomerase IIβ in Human H69 Cells
από: Pernille Grue, κ.ά.
Έκδοση: (1998)