Functional compatibility between isoform α and β of type II DNA topoisomerase
DNA topoisomerase II (topo II) plays a crucial role in controlling the conformation of both DNA and whole chromosomes. This activity is essential for several cellular events such as DNA replication, transcription, chromosome condensation and segregation. In mammals, two genes code for isoforms of to...
Uloženo v:
Hlavní autoři: | Ayako Sakaguchi, Akihiko Kikuchi |
---|---|
Médium: | Artigo |
Jazyk: | angličtina |
Vydáno: |
2004
|
On-line přístup: | https://doi.org/10.1242/jcs.00977 |
Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
|
Podobné jednotky
-
Involvement of DNA Topoisomerase IIβ in Neuronal Differentiation
Autor: Ken‐Ichiro Tsutsui, a další
Vydáno: (2001) -
The distribution and expression of the two isoforms of DNA topoisomerase II in normal and neoplastic human tissues
Autor: Helen Turley, a další
Vydáno: (1997) -
The α4 residues of human DNA topoisomerase IIα function in enzymatic activity and anticancer drug sensitivity
Autor: Suda, Namiko, a další
Vydáno: (2004) -
C-Terminal regions of topoisomerase IIα and IIβ determine isoform-specific functioning of the enzymes in vivo
Autor: Linka, René M., a další
Vydáno: (2007) -
Essential Mitotic Functions of DNA Topoisomerase IIα Are Not Adopted by Topoisomerase IIβ in Human H69 Cells
Autor: Pernille Grue, a další
Vydáno: (1998)