檢索結果 - Z. Dave Sharp

  • Showing 1 - 18 results of 18
Refine Results
  1. 1
    Evidence for Down-Regulation of Phosphoinositide 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR)-Dependent Translation Regulatory Signaling Pathways in Ames Dwarf Mice

    Evidence for Down-Regulation of Phosphoinositide 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR)-Dependent Translation Regulatory Signaling Pathways in Ames Dwarf Mice 由 Z. Dave Sharp, A. Bartke

    出版 2005
    獲取全文
    Artigo
    加到收藏夾
    Saved in:
  2. 2
    Rapamycin, the only drug that has been consistently demonstrated to increase mammalian longevity. An update

    Rapamycin, the only drug that has been consistently demonstrated to increase mammalian longevity. An update 由 Z. Dave Sharp, Randy Strong

    出版 2023
    獲取全文
    Revisão
    加到收藏夾
    Saved in:
  3. 3
    mTORC1 and p53

    mTORC1 and p53 由 Paul Hasty, Z. Dave Sharp, Tyler J. Curiel, Judith Campisi

    出版 2012
    獲取全文 獲取全文
    Artigo
    加到收藏夾
    Saved in:
  4. 4
    Expression of BRC Repeats in Breast Cancer Cells Disrupts the BRCA2-Rad51 Complex and Leads to Radiation Hypersensitivity and Loss of G2/M Checkpoint Control

    Expression of BRC Repeats in Breast Cancer Cells Disrupts the BRCA2-Rad51 Complex and Leads to Radiation Hypersensitivity and Loss of G2/M Checkpoint Control 由 Chi‐Fen Chen, Phang‐Lang Chen, Qing Zhong, Z. Dave Sharp, Wen‐Hwa Lee

    出版 1999
    獲取全文 獲取全文
    Artigo
    加到收藏夾
    Saved in:
  5. 5
    Divergent tissue and sex effects of rapamycin on the proteasome-chaperone network of old mice

    Divergent tissue and sex effects of rapamycin on the proteasome-chaperone network of old mice 由 Karl A. Rodriguez, Sherry G. Dodds, Randy Strong, Verónica Galván, Z. Dave Sharp, Rochelle Buffenstein

    出版 2014
    獲取全文 獲取全文
    Artigo
    加到收藏夾
    Saved in:
  6. 6
    The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment

    The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment 由 Phang‐Lang Chen, Chi‐Fen Chen, Yumay Chen, Jun Xiao, Z. Dave Sharp, Wen‐Hwa Lee

    出版 1998
    獲取全文
    Artigo
    加到收藏夾
    Saved in:
  7. 7
    The Nuclear Localization Sequences of the BRCA1 Protein Interact with the Importin-α Subunit of the Nuclear Transport Signal Receptor

    The Nuclear Localization Sequences of the BRCA1 Protein Interact with the Importin-α Subunit of the Nuclear Transport Signal Receptor 由 Chi‐Fen Chen, Shang Li, Yumay Chen, Phang‐Lang Chen, Z. Dave Sharp, Wen‐Hwa Lee

    出版 1996
    獲取全文 獲取全文
    Artigo
    加到收藏夾
    Saved in:
  8. 8
    Binding of CtIP to the BRCT Repeats of BRCA1 Involved in the Transcription Regulation of p21 Is Disrupted Upon DNA Damage

    Binding of CtIP to the BRCT Repeats of BRCA1 Involved in the Transcription Regulation of p21 Is Disrupted Upon DNA Damage 由 Shang Li, Phang‐Lang Chen, Thirugnana Subramanian, G. Chinnadurai, Gail E. Tomlinson, C. Kent Osborne, Z. Dave Sharp, Wen‐Hwa Lee

    出版 1999
    獲取全文 獲取全文
    Artigo
    加到收藏夾
    Saved in:
  9. 9
    Design of aging intervention studies: the NIA interventions testing program

    Design of aging intervention studies: the NIA interventions testing program 由 Nancy L. Nadon, Randy Strong, Richard A. Miller, James F. Nelson, Martin A. Javors, Z. Dave Sharp, Josep Maria Peralba, David E. Harrison

    出版 2008
    獲取全文
    Artigo
    加到收藏夾
    Saved in:
  10. 10
    Senescent Cells Contribute to the Physiological Remodeling of Aged Lungs

    Senescent Cells Contribute to the Physiological Remodeling of Aged Lungs 由 Cheresa Calhoun, Pooja Shivshankar, Mirna Saker, Lauren Sloane, Carolina B. Livi, Z. Dave Sharp, Carlos J. Orihuela, Serge Adnot, Eric S. White, Arlan Richardson, Claude Jourdan Le Saux

    出版 2015
    獲取全文
    Artigo
    加到收藏夾
    Saved in:
  11. 11
    Rapamycin extends life span of Rb1+/− mice by inhibiting neuroendocrine tumors

    Rapamycin extends life span of Rb1+/− mice by inhibiting neuroendocrine tumors 由 Carolina B. Livi, Rulon L. Hardman, Barbara A. Christy, Sherry G. Dodds, D.R. Jones, Charnae Williams, Randy Strong, Alex Bokov, Martin A. Javors, Yuji Ikeno, Gene B. Hubbard, Paul Hasty, Z. Dave Sharp

    出版 2013
    獲取全文
    Artigo
    加到收藏夾
    Saved in:
  12. 12
    Chronic <scp>mTOR</scp> inhibition in mice with rapamycin alters <scp>T</scp>,<scp> B</scp>, myeloid, and innate lymphoid cells and gut flora and prolongs life of immune‐deficient mice

    Chronic <scp>mTOR</scp> inhibition in mice with rapamycin alters <scp>T</scp>,<scp> B</scp>, myeloid, and innate lymphoid cells and gut flora and prolongs life of immune‐deficient... 由 Vincent Hurez, Vinh Dao, Aijie Liu, Srilakshmi Pandeswara, Jonathan Gelfond, Lishi Sun, Molly A. Bergman, Carlos J. Orihuela, Verónica Galván, Álvaro Padrón, Justin Drerup, Yang Liu, Paul Hasty, Z. Dave Sharp, Tyler J. Curiel

    出版 2015
    獲取全文 獲取全文
    Artigo
    加到收藏夾
    Saved in:
  13. 13
    Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

    Rapamycin fed late in life extends lifespan in genetically heterogeneous mice 由 David E. Harrison, Randy Strong, Z. Dave Sharp, James F. Nelson, Clinton M. Astle, Kevin Flurkey, Nancy L. Nadon, John E. Wilkinson, Krystyna Frenkel, Christy S. Carter, Marco Pahor, Martin A. Javors, Elizabeth Fernández, Richard A. Miller

    出版 2009
    獲取全文
    Artigo
    加到收藏夾
    Saved in:
  14. 14
    eRapa Restores a Normal Life Span in a FAP Mouse Model

    eRapa Restores a Normal Life Span in a FAP Mouse Model 由 Paul Hasty, Carolina B. Livi, Sherry G. Dodds, D.R. Jones, Randy Strong, Martin A. Javors, Kathleen E. Fischer, Lauren Sloane, Kruthi Murthy, Gene B. Hubbard, Lishi Sun, Vincent Hurez, Tyler J. Curiel, Z. Dave Sharp

    出版 2013
    獲取全文 獲取全文
    Artigo
    加到收藏夾
    Saved in:
  15. 15
    Rapamycin‐mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction

    Rapamycin‐mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction 由 Richard A. Miller, David E. Harrison, Clinton M. Astle, Elizabeth Fernández, Kevin Flurkey, Melissa Han, Martin A. Javors, Xinna Li, Nancy L. Nadon, James F. Nelson, Scott D. Pletcher, Adam B. Salmon, Z. Dave Sharp, Sabrina Van Roekel, Lynn Winkleman, Randy Strong

    出版 2013
    獲取全文
    Artigo
    加到收藏夾
    Saved in:
  16. 16
    Amplification of Distant Estrogen Response Elements Deregulates Target Genes Associated with Tamoxifen Resistance in Breast Cancer

    Amplification of Distant Estrogen Response Elements Deregulates Target Genes Associated with Tamoxifen Resistance in Breast Cancer 由 Pei-Yin Hsu, Hang-Kai Hsu, Xun Lan, Liran Juan, Pearlly S. Yan, Jadwiga Labanowska, Nyla A. Heerema, Tzu‐Hung Hsiao, Yu‐Chiao Chiu, Yidong Chen, Yunlong Liu, Lang Li, Rong Li, Ian M. Thompson, Kenneth P. Nephew, Z. Dave Sharp, Nameer B. Kirma, Victor X. Jin, Tim H.‐M. Huang

    出版 2013
    獲取全文
    Artigo
    加到收藏夾
    Saved in:
  17. 17
    Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice

    Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice 由 Richard A. Miller, David E. Harrison, Clinton M. Astle, Joseph A. Baur, Angela R. Boyd, Rafael de Cabo, Elizabeth Fernández, Kevin Flurkey, Martin A. Javors, James F. Nelson, Carlos J. Orihuela, Scott D. Pletcher, Z. Dave Sharp, David Sinclair, Joseph W. Starnes, John E. Wilkinson, Nancy L. Nadon, Randy Strong

    出版 2010
    獲取全文 獲取全文
    Artigo
    加到收藏夾
    Saved in:
  18. 18
    mTORC1 underlies age‐related muscle fiber damage and loss by inducing oxidative stress and catabolism

    mTORC1 underlies age‐related muscle fiber damage and loss by inducing oxidative stress and catabolism 由 Huibin Tang, Ken Inoki, Susan V. Brooks, Hideki Okazawa, Myung Lee, Junying Wang, Michael Kim, Catherine L. Kennedy, Peter Macpherson, Xuhuai Ji, Sabrina Van Roekel, Danielle Fraga, Kun Wang, Jinguo Zhu, Yoyo Wang, Z. Dave Sharp, Richard A. Miller, Thomas A. Rando, Daniel Goldman, Kun‐Liang Guan, Joseph B. Shrager

    出版 2019
    獲取全文 獲取全文
    Artigo
    加到收藏夾
    Saved in:

檢索工具: