Suchergebnisse - Yusheng Qu

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  1. 1
    Proarrhythmia Risk Assessment in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Using the Maestro MEA Platform

    Proarrhythmia Risk Assessment in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Using the Maestro MEA Platform von Yusheng Qu, Hugo M. Vargas

    Veröffentlicht 2015
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  2. 2
    Scientific Review of the Proarrhythmic Risks of Oligonucleotide Therapeutics: Are Dedicated <scp>ICH S7B</scp>/<scp>E14</scp> Studies Needed for Low‐Risk Modalities?

    Scientific Review of the Proarrhythmic Risks of Oligonucleotide Therapeutics: Are Dedicated <scp>ICH S7B</scp>/<scp>E14</scp> Studies Needed for Low‐Risk Modalities? von Yusheng Qu, Kim Henderson, Tod A. Harper, Hugo M. Vargas

    Veröffentlicht 2024
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  3. 3
    Longitudinal Changes in Prefrontal Cortex Activation Underlie Declines in Adolescent Risk Taking

    Longitudinal Changes in Prefrontal Cortex Activation Underlie Declines in Adolescent Risk Taking von Yusheng Qu, Adriana Galván, Andrew J. Fuligni, Matthew D. Lieberman, Eva H. Telzer

    Veröffentlicht 2015
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  4. 4
    Molecular Determinants of High Affinity Binding of α-Scorpion Toxin and Sea Anemone Toxin in the S3-S4 Extracellular Loop in Domain IV of the Na+ Channel α Subunit

    Molecular Determinants of High Affinity Binding of α-Scorpion Toxin and Sea Anemone Toxin in the S3-S4 Extracellular Loop in Domain IV of the Na+ Channel α Subunit von John C. Rogers, Yusheng Qu, Timothy N. Tanada, Todd Scheuer, William A. Catterall

    Veröffentlicht 1996
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  5. 5
    Interaction of batrachotoxin with the local anesthetic receptor site in transmembrane segment IVS6 of the voltage-gated sodium channel

    Interaction of batrachotoxin with the local anesthetic receptor site in transmembrane segment IVS6 of the voltage-gated sodium channel von Nancy J. Linford, Angela R. Cantrell, Yusheng Qu, Todd Scheuer, William A. Catterall

    Veröffentlicht 1998
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  6. 6
    Voltage Sensor–Trapping

    Voltage Sensor–Trapping von Sandrine Cestèle, Yusheng Qu, John C. Rogers, Hervé Rochat, Todd Scheuer, William A. Catterall

    Veröffentlicht 1998
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  7. 7
    Structure and Function of the Voltage Sensor of Sodium Channels Probed by a β-Scorpion Toxin

    Structure and Function of the Voltage Sensor of Sodium Channels Probed by a β-Scorpion Toxin von Sandrine Cestèle, Vladimir Yarov‐Yarovoy, Yusheng Qu, Franĉois Sampiéri, Todd Scheuer, William A. Catterall

    Veröffentlicht 2006
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  8. 8
    Blinded In Silico Drug Trial Reveals the Minimum Set of Ion Channels for Torsades de Pointes Risk Assessment

    Blinded In Silico Drug Trial Reveals the Minimum Set of Ion Channels for Torsades de Pointes Risk Assessment von Xin Zhou, Yusheng Qu, Elisa Passini, Alfonso Bueno‐Orovio, Yang Liu, Hugo M. Vargas, Blanca Rodríguez

    Veröffentlicht 2020
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  9. 9
    Molecular Determinants of Vanilloid Sensitivity in TRPV1

    Molecular Determinants of Vanilloid Sensitivity in TRPV1 von Narender R. Gavva, Lana Klionsky, Yusheng Qu, Licheng Shi, Rami Tamir, Steve Edenson, T. J. Zhang, Vellarkad N. Viswanadhan, Attila Tóth, Larry V. Pearce, Todd W. Vanderah, Frank Porreca, Peter M. Blumberg, Jack D. Lile, Yax Sun, Ken Wild, Jean-Claude Louis, James Treanor

    Veröffentlicht 2004
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  10. 10
    Nonclinical cardiovascular safety evaluation of romosozumab, an inhibitor of sclerostin for the treatment of osteoporosis in postmenopausal women at high risk of fracture

    Nonclinical cardiovascular safety evaluation of romosozumab, an inhibitor of sclerostin for the treatment of osteoporosis in postmenopausal women at high risk of fracture von James R. Turk, Aimée M. Deaton, Jun Yin, Marina Stolina, Melanie Felx, Gabrielle Boyd, Jean-Guy Bienvenu, Aurore Varela, Martin Guillot, Gill Holdsworth, Alison Wolfreys, Denise Dwyer, Sheetal Kumar, Emily M. de Koning, Yusheng Qu, Michael J. Engwall, Kathrin Locher, Lucas D. Ward, Charles Glaus, Yudong D. He, Rogely Boyce

    Veröffentlicht 2020
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  11. 11
    Cardiovascular response to small-molecule APJ activation

    Cardiovascular response to small-molecule APJ activation von Brandon Ason, Yinhong Chen, Qi Guo, Kimberly M. Hoagland, Ray W. Chui, Mark R. Fielden, Weston Sutherland, Rhonda Chen, Ying Zhang, Shirley Mihardja, Xiaochuan Ma, Xun Li, Yaping Sun, Dongming Liu, Khanh Q. Nguyen, Jinghong Wang, Ning Li, Sridharan Rajamani, Yusheng Qu, BaoXi Gao, Andrea M. Boden, Vishnu Chintalgattu, J. R. Turk, Joyce Chan, Liaoyuan A. Hu, Paul J. Dransfield, Jonathan B. Houze, Jingman Wong, Ji Ma, Vatee Pattaropong, Murielle M. Véniant, Hugo M. Vargas, Gayathri Swaminath, Aarif Y. Khakoo

    Veröffentlicht 2020
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  12. 12
    Time for a Fully Integrated Nonclinical–Clinical Risk Assessment to Streamline QT Prolongation Liability Determinations: A Pharma Industry Perspective

    Time for a Fully Integrated Nonclinical–Clinical Risk Assessment to Streamline QT Prolongation Liability Determinations: A Pharma Industry Perspective von Hugo M. Vargas, Michael G. Rolf, Todd Wisialowski, William E. Achanzar, Anthony Bahinski, Alan Bass, Charles T. Benson, Khuram W. Chaudhary, Nicolas Couvreur, Corina Dota, Michael J. Engwall, C. Michael Foley, David J. Gallacher, Andrea Greiter‐Wilke, Jean‐Michel Guillon, Brian D. Guth, Herbert M. Himmel, Christa Hegele‐Hartung, Maki Ito, Stephen Jenkinson, Katsuyoshi Chiba, Armando Lagrutta, Paul Lévesque, Eric Martel, Yoshiko Okai, Ravikumar Peri, Amy Pointon, Yusheng Qu, Ard Teisman, Martin Traebert, Takashi Yoshinaga, Gary A. Gintant, Derek J. Leishman, Jean‐Pierre Valentin

    Veröffentlicht 2020
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