Výsledky vyhledávání - Yulia Jitkova

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  1. 1
    A Novel Formulation of Tigecycline Has Enhanced Stability and Sustained Antibacterial and Antileukemic Activity

    A Novel Formulation of Tigecycline Has Enhanced Stability and Sustained Antibacterial and Antileukemic Activity Autor Yulia Jitkova, Marcela Gronda, Rose Hurren, Xiaoming Wang, Carolyn A. Goard, Bozhena Jhas, Aaron D. Schimmer

    Vydáno 2014
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  2. 2
    A Phase 1 study of intravenous infusions of tigecycline in patients with acute myeloid leukemia

    A Phase 1 study of intravenous infusions of tigecycline in patients with acute myeloid leukemia Autor Gregory A. Reed, Gary J. Schiller, Suman Kambhampati, Martin S. Tallman, Dan Douer, Mark D. Minden, Karen Yee, Vikas Gupta, Joseph Brandwein, Yulia Jitkova, Marcela Gronda, Rose Hurren, Aisha Shamas‐Din, Andre C. Schuh, Aaron D. Schimmer

    Vydáno 2016
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  3. 3
    Venetoclax enhances T cell–mediated antileukemic activity by increasing ROS production

    Venetoclax enhances T cell–mediated antileukemic activity by increasing ROS production Autor Jong Bok Lee, Dilshad H. Khan, Rose Hurren, Mingjing Xu, Yoosu Na, Hyeonjeong Kang, Sara Mirali, Xiaoming Wang, Marcela Gronda, Yulia Jitkova, Neil MacLean, Andrea Arruda, Zoe Alaniz, Marina Konopleva, Michael Andreeff, Mark D. Minden, Zhang Li, Aaron D. Schimmer

    Vydáno 2021
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  4. 4
    Wnt Inhibitor Screen Reveals Iron Dependence of β-Catenin Signaling in Cancers

    Wnt Inhibitor Screen Reveals Iron Dependence of β-Catenin Signaling in Cancers Autor Siyuan Song, Tania Christova, Stephen Perusini, Solmaz Alizadeh, Ren-Yue Bao, Bryan W. Miller, Rose Hurren, Yulia Jitkova, Marcela Gronda, Methvin Isaac, Babu Joseph, Ratheesh Subramaniam, Ahmed Aman, Anh Chau, Donna E. Hogge, Scott J. Weir, James M. Kasper, Aaron D. Schimmer, Rima Al‐awar, Jeffrey L. Wrana, Liliana Attisano

    Vydáno 2011
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  5. 5
    Oral ciclopirox olamine displays biological activity in a phase I study in patients with advanced hematologic malignancies

    Oral ciclopirox olamine displays biological activity in a phase I study in patients with advanced hematologic malignancies Autor Mark D. Minden, Donna E. Hogge, Scott J. Weir, Jim Kasper, Debra Webster, Lavonne Patton, Yulia Jitkova, Rose Hurren, Marcela Gronda, Carolyn A. Goard, Lian Rajewski, John L. Haslam, Kathleen E. Heppert, Kevin Schorno, Hong Chang, Joseph Brandwein, Vikas Gupta, Andre C. Schuh, Suzanne Trudel, Karen Yee, Gregory A. Reed, Aaron D. Schimmer

    Vydáno 2013
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  6. 6
    AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress

    AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress Autor Shrivani Sriskanthadevan, Danny V. Jeyaraju, Timothy Chung, Swayam Prabha, Wei Xu, Marko Škrtić, Bozhena Jhas, Rose Hurren, Marcela Gronda, Xiaoming Wang, Yulia Jitkova, Mahadeo A. Sukhai, Feng-Hsu Lin, Neil MacLean, Rob C. Laister, Carolyn A. Goard, Peter Mullen, Stephanie Z. Xie, Linda Z. Penn, Ian M. Rogers, John E. Dick, Mark D. Minden, Aaron D. Schimmer

    Vydáno 2015
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  7. 7
    Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal

    Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal Autor Rashim Pal Singh, Danny V. Jeyaraju, Véronique Voisin, Rose Hurren, Changjiang Xu, James R. Hawley, Samir H. Barghout, Dilshad H. Khan, Marcela Gronda, Xiaoming Wang, Yulia Jitkova, David Sharon, Sanduni Liyanagae, Neil MacLean, Ayesh K. Seneviratene, Sara Mirali, Adina Borenstein, Geethu Emily Thomas, Joelle Soriano, Elias Orouji, Mark D. Minden, Andrea Arruda, Steven M. Chan, Gary D. Bader, Mathieu Lupien, Aaron D. Schimmer

    Vydáno 2020
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  8. 8
    Inhibition of Mitochondrial Translation as a Therapeutic Strategy for Human Acute Myeloid Leukemia

    Inhibition of Mitochondrial Translation as a Therapeutic Strategy for Human Acute Myeloid Leukemia Autor Marko Škrtić, Shrivani Sriskanthadevan, Bozhena Jhas, Marinella Gebbia, Xiaoming Wang, Zezhou Wang, Rose Hurren, Yulia Jitkova, Marcela Gronda, Neil MacLean, Courteney K. Lai, Yanina Eberhard, Justyna Bartoszko, Paul A. Spagnuolo, Angela C. Rutledge, Alessandro Datti, Troy Ketela, Jason Moffat, Brian H. Robinson, Jessie Cameron, Jeffery L. Wrana, Connie J. Eaves, Mark D. Minden, Jean Wang, John E. Dick, R. Keith Humphries, Corey Nislow, Guri Giaever, Aaron D. Schimmer

    Vydáno 2011
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  9. 9
    Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality

    Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality Autor Jo Ishizawa, Sarah F. Zarabi, R. Eric Davis, Ondrej Halgas, Takenobu Nii, Yulia Jitkova, Ran Zhao, Jonathan St‐Germain, Lauren Heese, Grace Egan, Vivian Ruvolo, Samir H. Barghout, Yuki Nishida, Rose Hurren, Wencai Ma, Marcela Gronda, Todd Link, Keith S. Wong, Mark Mabanglo, Kensuke Kojima, Gautam Borthakur, Neil MacLean, Man Chun John, Andrew B. Leber, Mark D. Minden, Walid A. Houry, Hagop M. Kantarjian, Martin Stogniew, Brian Raught, E.F. Pai, Aaron D. Schimmer, Michael Andreeff

    Vydáno 2019
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  10. 10
    Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia

    Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia Autor Alicia M. Cole, Zezhou Wang, Étienne Coyaud, Véronique Voisin, Marcela Gronda, Yulia Jitkova, Rachel Mattson, Rose Hurren, Sonja Babovic, Neil MacLean, Ian J. Restall, Xiaoming Wang, Danny V. Jeyaraju, Mahadeo A. Sukhai, Swayam Prabha, Shaheena Bashir, Ashwin Ramakrishnan, Elisa Leung, Yi Hua Qia, Nianxian Zhang, Kevin R. Combes, Troy Ketela, Fengshu Lin, Walid A. Houry, Ahmed Aman, Rima Al‐awar, Wei Zheng, Erno Wienholds, Chang Xu, John E. Dick, Jean Wang, Jason Moffat, Mark D. Minden, Connie J. Eaves, Gary D. Bader, Zhenyue Hao, Steven M. Kornblau, Brian Raught, Aaron D. Schimmer

    Vydáno 2015
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  11. 11
    The Mitochondrial Transacylase, Tafazzin, Regulates AML Stemness by Modulating Intracellular Levels of Phospholipids

    The Mitochondrial Transacylase, Tafazzin, Regulates AML Stemness by Modulating Intracellular Levels of Phospholipids Autor Ayesh K. Seneviratne, Mingjing Xu, Juan J. Aristizabal Henao, Val A. Fajardo, Zhenyue Hao, Véronique Voisin, G. Wei Xu, Rose Hurren, S. Kim, Neil MacLean, Xiaoming Wang, Marcela Gronda, Danny V. Jeyaraju, Yulia Jitkova, Troy Ketela, Michael Mullokandov, David Sharon, Geethu Emily Thomas, Raphaël Chouinard‐Watkins, James R. Hawley, Caitlin Schafer, Helen Loo Yau, Zaza Khuchua, Ahmed Aman, Rima Al‐awar, Atan Gross, Steven M. Claypool, Richard P. Bazinet, Mathieu Lupien, Steven M. Chan, Daniel D. De Carvalho, Mark D. Minden, Gary D. Bader, Ken D. Stark, Paul J. LeBlanc, Aaron D. Schimmer

    Vydáno 2019
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  12. 12
    Mapping the Cellular Response to Small Molecules Using Chemogenomic Fitness Signatures

    Mapping the Cellular Response to Small Molecules Using Chemogenomic Fitness Signatures Autor Anna Y. Lee, Robert P. St.Onge, Michael Proctor, Iain M. Wallace, Aaron H. Nile, Paul A. Spagnuolo, Yulia Jitkova, Marcela Gronda, Yan Wu, Moshe K. Kim, Kahlin Cheung-Ong, Nikko P. Torres, Eric D. Spear, Mitchell K. L. Han, Ulrich Schlecht, Sundari Suresh, Geoffrey Duby, Lawrence E. Heisler, Anuradha Surendra, Eula Fung, Malene L. Urbanus, Marinella Gebbia, Elena Lissina, Molly Miranda, Jennifer Chiang, Ana M. Aparicio, Mahel Zeghouf, Ronald W. Davis, Jacqueline Cherfils, Marc Boutry, Chris A. Kaiser, Carolyn L. Cummins, William S. Trimble, Grant W. Brown, Aaron D. Schimmer, Vytas A. Bankaitis, Corey Nislow, Gary D. Bader, Guri Giaever

    Vydáno 2014
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  13. 13
    Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia

    Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia Autor Qi Zhang, Bridget Riley‐Gillis, Lina Han, Yannan Jia, Alessia Lodi, Haijiao Zhang, Saravanan Ganesan, Rongqing Pan, Sergej Konoplev, Shannon Sweeney, Jeremy Ryan, Yulia Jitkova, Kenneth Dunner, Shaun Grosskurth, Priyanka Vijay, Sujana Ghosh, Charles Lu, Wencai Ma, Stephen E. Kurtz, Vivian Ruvolo, Helen Ma, Connie C. Weng, Cassandra L. Ramage, Natalia Baran, Ce Shi, Tianyu Cai, R. Eric Davis, Venkata Lokesh Battula, Yingchang Mi, Jing Wang, Courtney D. DiNardo, Michael Andreeff, Jeffery W. Tyner, Aaron D. Schimmer, Anthony Letai, Rose Ann Padua, Carlos E. Bueso‐Ramos, Stefano Tiziani, Joel D. Leverson, Relja Popovic, Marina Konopleva

    Vydáno 2022
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