Resultados da pesquisa - Young‐Sam Lee

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  1. 1
    Human Pol ζ purified with accessory subunits is active in translesion DNA synthesis and complements Pol η in cisplatin bypass

    Human Pol ζ purified with accessory subunits is active in translesion DNA synthesis and complements Pol η in cisplatin bypass Por Young‐Sam Lee, Mark Gregory, Wei Yang

    Publicado em 2014
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  2. 2
    How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis

    How a homolog of high-fidelity replicases conducts mutagenic DNA synthesis Por Young‐Sam Lee, Yang Gao, Wei Yang

    Publicado em 2015
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  3. 3
    Structural Insight into Processive Human Mitochondrial DNA Synthesis and Disease-Related Polymerase Mutations

    Structural Insight into Processive Human Mitochondrial DNA Synthesis and Disease-Related Polymerase Mutations Por Young-Sam Lee, William Kennedy, Y. Whitney Yin

    Publicado em 2009
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  4. 4
    SAICAR Stimulates Pyruvate Kinase Isoform M2 and Promotes Cancer Cell Survival in Glucose-Limited Conditions

    SAICAR Stimulates Pyruvate Kinase Isoform M2 and Promotes Cancer Cell Survival in Glucose-Limited Conditions Por Kirstie E. Keller, Irene S. Tan, Young‐Sam Lee

    Publicado em 2012
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  5. 5
    Selective immobilization of proteins to self-assembled monolayers presenting active site-directed capture ligands

    Selective immobilization of proteins to self-assembled monolayers presenting active site-directed capture ligands Por Christian D. Hodneland, Young-Sam Lee, Dal‐Hee Min, Milan Mrksich

    Publicado em 2002
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  6. 6
    SAICAR Induces Protein Kinase Activity of PKM2 that Is Necessary for Sustained Proliferative Signaling of Cancer Cells

    SAICAR Induces Protein Kinase Activity of PKM2 that Is Necessary for Sustained Proliferative Signaling of Cancer Cells Por Kirstie E. Keller, Zainab M. Doctor, Zachary W. Dwyer, Young‐Sam Lee

    Publicado em 2014
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  7. 7
    Molecular basis of cyclin-CDK-CKI regulation by reversible binding of an inositol pyrophosphate

    Molecular basis of cyclin-CDK-CKI regulation by reversible binding of an inositol pyrophosphate Por Young‐Sam Lee, Kexin Huang, Florante A. Quiocho, Erin K. O’Shea

    Publicado em 2007
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  8. 8
    Regulation of a Cyclin-CDK-CDK Inhibitor Complex by Inositol Pyrophosphates

    Regulation of a Cyclin-CDK-CDK Inhibitor Complex by Inositol Pyrophosphates Por Young‐Sam Lee, Sashidhar Mulugu, John D. York, Erin K. O’Shea

    Publicado em 2007
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  9. 9
    Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulin

    Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulin Por Qing Guo, Yuequan Shen, Young-Sam Lee, Craig S. Gibbs, Milan Mrksich, Wei‐Jen Tang

    Publicado em 2005
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  10. 10
    Structural and mechanistic studies of polymerase η bypass of phenanthriplatin DNA damage

    Structural and mechanistic studies of polymerase η bypass of phenanthriplatin DNA damage Por Mark Gregory, Ga Young Park, Timothy C. Johnstone, Young‐Sam Lee, Wei Yang, Stephen J. Lippard

    Publicado em 2014
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  11. 11
    Structure-based Inhibitor Discovery against Adenylyl Cyclase Toxins from Pathogenic Bacteria That Cause Anthrax and Whooping Cough

    Structure-based Inhibitor Discovery against Adenylyl Cyclase Toxins from Pathogenic Bacteria That Cause Anthrax and Whooping Cough Por Sandriyana Soelaiman, BinQing Wei, Pamela Bergson, Young-Sam Lee, Yuequan Shen, Milan Mrksich, Brian K. Shoichet, Wei‐Jen Tang

    Publicado em 2003
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  12. 12
    Structural basis for processivity and antiviral drug toxicity in human mitochondrial <scp>DNA</scp> replicase

    Structural basis for processivity and antiviral drug toxicity in human mitochondrial <scp>DNA</scp> replicase Por Michał R. Szymański, Vladmir B Kuznetsov, Christie K. Shumate, Qingchao Meng, Young‐Sam Lee, Gayatri Patel, Smita S. Patel, Y. Whitney Yin

    Publicado em 2015
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  13. 13
    Chemical screening identifies ROCK as a target for recovering mitochondrial function in Hutchinson-Gilford progeria syndrome

    Chemical screening identifies ROCK as a target for recovering mitochondrial function in Hutchinson-Gilford progeria syndrome Por Hyun Tae Kang, Joon Tae Park, Kobong Choi, Hyo Jei Claudia Choi, Chul Won Jung, Gyu Ree Kim, Young‐Sam Lee, Sang Chul Park

    Publicado em 2017
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  14. 14
    Nintedanib induces senolytic effect via STAT3 inhibition

    Nintedanib induces senolytic effect via STAT3 inhibition Por Hyun-Ji Cho, Jeong-A Hwang, Eun Jae Yang, Eok-Cheon Kim, Jae‐Ryong Kim, Sung Young Kim, Young Zoon Kim, Sang Chul Park, Young‐Sam Lee

    Publicado em 2022
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  15. 15
    Structure-guided discovery of the metabolite carboxy-SAM that modulates tRNA function

    Structure-guided discovery of the metabolite carboxy-SAM that modulates tRNA function Por Jungwook Kim, Hui Xiao, J.B. Bonanno, Chakrapani Kalyanaraman, Shoshana Brown, Xiang‐Ying Tang, Nawar Al-Obaidi, Y. Patskovsky, Patricia C. Babbitt, Matthew P. Jacobson, Young-Sam Lee, Steven C. Almo

    Publicado em 2013
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  16. 16
    Transplantation of Endothelial Progenitor Cells Accelerates Dermal Wound Healing with Increased Recruitment of Monocytes/Macrophages and Neovascularization

    Transplantation of Endothelial Progenitor Cells Accelerates Dermal Wound Healing with Increased Recruitment of Monocytes/Macrophages and Neovascularization Por Wonhee Suh, Koung Li Kim, Jeong‐Min Kim, In‐Soon Shin, Young‐Sam Lee, Jae‐Young Lee, Hyung‐Suk Jang, Jung‐Sun Lee, Jonghoe Byun, Jin‐Ho Choi, Eun‐Seok Jeon, Duk‐Kyung Kim

    Publicado em 2005
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  17. 17
    ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes

    ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes Por Hyein Lee, Sukhee Cho, Mi-Jin Kim, Yeo Jin Park, Eunji Cho, Yeon Suk Jo, Yong‐Seok Kim, Jung Yi Lee, Themis Thoudam, Seung‐Hwa Woo, Se-In Lee, Juyeong Jeon, Young‐Sam Lee, Byung‐Chang Suh, Jong Hyuk Yoon, Younghoon Go, In-Kyu Lee, Jinsoo Seo

    Publicado em 2023
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  18. 18
    Disruption of nucleocytoplasmic trafficking as a cellular senescence driver

    Disruption of nucleocytoplasmic trafficking as a cellular senescence driver Por Ji-Hwan Park, Sung Jin Ryu, Byung Ju Kim, Hyun-Ji Cho, Choon Park, Hyo Jei Claudia Choi, Eunjin Jang, Eun Jae Yang, Jeong-A Hwang, Seung‐Hwa Woo, Jun Hyung Lee, Ji Hwan Park, Kyung-Mi Choi, Young‐Yon Kwon, Cheol‐Koo Lee, Joon Tae Park, Sung Chun Cho, Yun‐Il Lee, Sung Bae Lee, Jeong A. Han, Kyung A Cho, Min‐Sik Kim, Daehee Hwang, Young‐Sam Lee, Sang Chul Park

    Publicado em 2021
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