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  1. 1
    ApoE (Apolipoprotein E) in Brain Pericytes Regulates Endothelial Function in an Isoform-Dependent Manner by Modulating Basement Membrane Components

    ApoE (Apolipoprotein E) in Brain Pericytes Regulates Endothelial Function in an Isoform-Dependent Manner by Modulating Basement Membrane Components 由 Yu Yamazaki, Mitsuru Shinohara, Akari Yamazaki, Yingxue Ren, Yan W. Asmann, Takahisa Kanekiyo, Guojun Bu

    出版 2019
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  2. 2
    Lipocalin-2 protects the brain during inflammatory conditions

    Lipocalin-2 protects the brain during inflammatory conditions 由 Seok Seon Kang, Yingxue Ren, Chia‐Chen Liu, Aishe Kurti, Katherine E. Baker, Guojun Bu, Yan W. Asmann, John Denis Fryer

    出版 2017
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  3. 3
    HLA class-I and class-II restricted neoantigen loads predict overall survival in breast cancer

    HLA class-I and class-II restricted neoantigen loads predict overall survival in breast cancer 由 Yingxue Ren, Yesesri Cherukuri, Daniel P. Wickland, Vivekananda Sarangi, Shulan Tian, Jodi M. Carter, Aaron S. Mansfield, Matthew S. Block, Mark E. Sherman, Keith L. Knutson, Yi Lin, Yan W. Asmann

    出版 2020
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  4. 4
    APOE deficiency impacts neural differentiation and cholesterol biosynthesis in human iPSC-derived cerebral organoids

    APOE deficiency impacts neural differentiation and cholesterol biosynthesis in human iPSC-derived cerebral organoids 由 Jing Zhao, Tadafumi C. Ikezu, Wenyan Lü, Jesse R. Macyczko, Yonghe Li, Laura J. Lewis‐Tuffin, Yuka A. Martens, Yingxue Ren, Yiyang Zhu, Yan W. Asmann, Nilüfer Ertekin‐Taner, Takahisa Kanekiyo, Guojun Bu

    出版 2023
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  5. 5
    ABCA7 haplodeficiency disturbs microglial immune responses in the mouse brain

    ABCA7 haplodeficiency disturbs microglial immune responses in the mouse brain 由 Tomonori Aikawa, Yingxue Ren, Yu Yamazaki, Masaya Tachibana, Madeleine R. Johnson, Casey T. Anderson, Yuka A. Martens, Marie‐Louise Holm, Yan W. Asmann, Takashi Saito, Takaomi C. Saido, Michael L. Fitzgerald, Guojun Bu, Takahisa Kanekiyo

    出版 2019
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  6. 6
    Vascular ApoE4 Impairs Behavior by Modulating Gliovascular Function

    Vascular ApoE4 Impairs Behavior by Modulating Gliovascular Function 由 Yu Yamazaki, Chia‐Chen Liu, Akari Yamazaki, Francis Shue, Yuka A. Martens, Yuanxin Chen, Wenhui Qiao, Aishe Kurti, Hiroshi Oue, Yingxue Ren, Ying Li, Tomonori Aikawa, Yesesri Cherukuri, John Denis Fryer, Yan W. Asmann, Betty Y.S. Kim, Takahisa Kanekiyo, Guojun Bu

    出版 2020
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  7. 7
    ABCA7 deficiency causes neuronal dysregulation by altering mitochondrial lipid metabolism

    ABCA7 deficiency causes neuronal dysregulation by altering mitochondrial lipid metabolism 由 Keiji Kawatani, Marie‐Louise Holm, Skylar C Starling, Yuka A. Martens, Jing Zhao, Wenyan Lü, Yingxue Ren, Zonghua Li, Peizhou Jiang, Yangying Jiang, Samantha K. Baker, Ni Wang, Bhaskar Roy, Tammee M. Parsons, Ralph B. Perkerson, Hanmei Bao, Xianlin Han, Guojun Bu, Takahisa Kanekiyo

    出版 2023
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  8. 8
    Alzheimer's disease risk ABCA7 p.A696S variant disturbs the microglial response to amyloid pathology in mice

    Alzheimer's disease risk ABCA7 p.A696S variant disturbs the microglial response to amyloid pathology in mice 由 Xiaoye Ma, Dmitry Prokopenko, Ni Wang, Tomonori Aikawa, Younjung Choi, Can Zhang, Dan Lei, Yingxue Ren, Keiji Kawatani, Skylar C Starling, Ralph B. Perkerson, Bhaskar Roy, Astrid Quintero, Tammee M. Parsons, Yining Pan, Zonghua Li, Minghui Wang, Hanmei Bao, Xianlin Han, Guojun Bu, Rudolph E. Tanzi, Takahisa Kanekiyo

    出版 2025
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  9. 9
    Neuronal ABCA7 deficiency aggravates mitochondrial dysfunction and neurodegeneration in Alzheimer's disease

    Neuronal ABCA7 deficiency aggravates mitochondrial dysfunction and neurodegeneration in Alzheimer's disease 由 Ni Wang, Yining Pan, Skylar C Starling, Devon H. Haskell, Astrid Quintero, Keiji Kawatani, Yasuteru Inoue, Francis Shue, Xiaoye Ma, Tomonori Aikawa, Yuka A. Martens, Aishe Kurti, Tammee M. Parsons, Ralph B. Perkerson, Bhaskar Roy, Ana‐Caroline Raulin, Yingxue Ren, Michael DeTure, Dennis W. Dickson, Hanmei Bao, Xianlin Han, Guojun Bu, Takahisa Kanekiyo

    出版 2025
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  10. 10
    Loss of TMEM106B leads to myelination deficits: implications for frontotemporal dementia treatment strategies

    Loss of TMEM106B leads to myelination deficits: implications for frontotemporal dementia treatment strategies 由 Xiaolai Zhou, Alexandra M. Nicholson, Yingxue Ren, Mieu Brooks, Peizhou Jiang, Aamir Zuberi, Hung Nguyen Phuoc, Ralph B. Perkerson, Billie J. Matchett, Tammee M. Parsons, NiCole A. Finch, Wen-Lang Lin, Wenhui Qiao, Monica Castanedes‐Casey, Virginia Phillips, Ariston L Librero, Yan W. Asmann, Guojun Bu, Melissa E. Murray, Cathleen Lutz, Dennis W. Dickson, Rosa Rademakers

    出版 2020
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  11. 11
    APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer’s disease patient iPSC-derived cerebral organoids

    APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer’s disease patient iPSC-derived cerebral organoids 由 Jing Zhao, Yuan Fu, Yu Yamazaki, Yingxue Ren, Mary Dabney Davis, Chia‐Chen Liu, Wenyan Lü, Xue Wang, Kai Chen, Yesesri Cherukuri, Lin Jia, Yuka A. Martens, Lucy Job, Francis Shue, Thanh Thanh L. Nguyen, Steven G. Younkin, Neill R. Graff‐Radford, Zbigniew K. Wszołek, David A. Brafman, Yan W. Asmann, Nilüfer Ertekin‐Taner, Takahisa Kanekiyo, Guojun Bu

    出版 2020
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  12. 12
    Apolipoprotein E regulates lipid metabolism and α-synuclein pathology in human iPSC-derived cerebral organoids

    Apolipoprotein E regulates lipid metabolism and α-synuclein pathology in human iPSC-derived cerebral organoids 由 Jing Zhao, Wenyan Lü, Yingxue Ren, Yuan Fu, Yuka A. Martens, Francis Shue, Mary Dabney Davis, Xue Wang, Kai Chen, Fuyao Li, Chia‐Chen Liu, Neill R. Graff‐Radford, Zbigniew K. Wszołek, Steven G. Younkin, David A. Brafman, Nilüfer Ertekin‐Taner, Yan W. Asmann, Dennis W. Dickson, Ziying Xu, Meixia Pan, Xianlin Han, Takahisa Kanekiyo, Guojun Bu

    出版 2021
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  13. 13
    Extensive transcriptomic study emphasizes importance of vesicular transport in C9orf72 expansion carriers

    Extensive transcriptomic study emphasizes importance of vesicular transport in C9orf72 expansion carriers 由 Dennis W. Dickson, Matthew Baker, Jazmyne L. Jackson, Mariely DeJesus‐Hernandez, NiCole A. Finch, Shulan Tian, Michael G. Heckman, Cyril Pottier, Tania F. Gendron, Melissa E. Murray, Yingxue Ren, Joseph S. Reddy, Neill R. Graff‐Radford, Bradley F. Boeve, Ronald C. Petersen, David S. Knopman, Keith A. Josephs, Leonard Petrucelli, Björn Oskarsson, John W. Sheppard, Yan W. Asmann, Rosa Rademakers, Marka van Blitterswijk

    出版 2019
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  14. 14
    APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid

    APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid 由 Na Zhao, Olivia N. Attrebi, Yingxue Ren, Wenhui Qiao, Berkiye Sonustun, Yuka A. Martens, Axel Meneses, Fuyao Li, Francis Shue, Jiaying Zheng, Alexandra J. Van Ingelgom, Mary Dabney Davis, Aishe Kurti, Joshua A. Knight, Cynthia Linares, Yixing Chen, Marion Delenclos, Chia‐Chen Liu, John Denis Fryer, Yan W. Asmann, Pamela J. McLean, Dennis W. Dickson, Owen A. Ross, Guojun Bu

    出版 2020
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  15. 15
    CSF biomarkers of immune activation and Alzheimer’s disease for predicting cognitive impairment risk in the elderly

    CSF biomarkers of immune activation and Alzheimer’s disease for predicting cognitive impairment risk in the elderly 由 Francis Shue, Launia J. White, Rachel Hendrix, Jason D. Ulrich, Rachel L. Henson, William D. Knight, Yuka A. Martens, Ni Wang, Bhaskar Roy, Skylar C Starling, Yingxue Ren, Chengjie Xiong, Yan W. Asmann, Jeremy A. Syrjanen, Maria Vassilaki, Michelle M. Mielke, Jigyasha Timsina, Yun Ju Sung, Carlos Cruchaga, David M. Holtzman, Guojun Bu, Ronald C. Petersen, Michael G. Heckman, Takahisa Kanekiyo

    出版 2024
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  16. 16
    Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia

    Elevating microglia TREM2 reduces amyloid seeding and suppresses disease-associated microglia 由 Na Zhao, Wenhui Qiao, Fuyao Li, Yingxue Ren, Jiaying Zheng, Yuka A. Martens, Xusheng Wang, Ling Li, Chia‐Chen Liu, Kai Chen, Yiyang Zhu, Tadafumi C. Ikezu, Zonghua Li, Axel Meneses, Yunjung Jin, Joshua A. Knight, Yixing Chen, Ligia I. Bastea, Cynthia Linares, Berkiye Sonustun, Lucy Job, Madeleine L. Smith, Manling Xie, Yong Liu, Anthony D. Umpierre, Koichiro Haruwaka, Zachary Quicksall, Peter Störz, Yan W. Asmann, Long‐Jun Wu, Guojun Bu

    出版 2022
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  17. 17
    TYROBP genetic variants in early-onset Alzheimer's disease

    TYROBP genetic variants in early-onset Alzheimer's disease 由 Cyril Pottier, Thomas A. Ravenscroft, Patricia H. Brown, NiCole A. Finch, Matt Baker, Meeia Parsons, Yan W. Asmann, Yingxue Ren, Elizabeth Christopher, Denise Levitch, Marka van Blitterswijk, Carlos Cruchaga, Dominique Campion, Gaël Nicolas, Anne-Claire Richard, Rita Guerreiro, José Brás, Stephan Züchner, Michael Gonzalez, Guojun Bu, Steven G. Younkin, David S. Knopman, Keith A. Josephs, Joseph E. Parisi, Ronald C. Petersen, Nilüfer Ertekin‐Taner, Neill R. Graff‐Radford, Bradley F. Boeve, Dennis W. Dickson, Rosa Rademakers

    出版 2016
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  18. 18
    Alzheimer’s Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways

    Alzheimer’s Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways 由 Na Zhao, Yingxue Ren, Yu Yamazaki, Wenhui Qiao, Fuyao Li, Lindsey M. Felton, Siamak MahmoudianDehkordi, Alexandra Kueider‐Paisley, Berkiye Sonoustoun, Matthias Arnold, Francis Shue, Jiaying Zheng, Olivia N. Attrebi, Yuka A. Martens, Zonghua Li, Ligia I. Bastea, Axel Meneses, Kai Chen, Paul M. Thompson, Lisa St. John‐Williams, Masaya Tachibana, Tomonori Aikawa, Hiroshi Oue, Lucy Job, Akari Yamazaki, Chia‐Chen Liu, Peter Störz, Yan W. Asmann, Nilüfer Ertekin‐Taner, Takahisa Kanekiyo, Rima Kaddurah‐Daouk, Guojun Bu

    出版 2020
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  19. 19
    Peripheral apoE4 enhances Alzheimer’s pathology and impairs cognition by compromising cerebrovascular function

    Peripheral apoE4 enhances Alzheimer’s pathology and impairs cognition by compromising cerebrovascular function 由 Chia‐Chen Liu, Jing Zhao, Yuan Fu, Yasuteru Inoue, Yingxue Ren, Yuanxin Chen, Sydney V. Doss, Francis Shue, Suren Jeevaratnam, Ligia I. Bastea, Na Wang, Yuka A. Martens, Wenhui Qiao, Minghui Wang, Na Zhao, Lin Jia, Yu Yamazaki, Akari Yamazaki, Cassandra L. Rosenberg, Zhen Wang, Dehui Kong, Zonghua Li, Lindsey A. Kuchenbecker, Zachary A. Trottier, Lindsey M. Felton, Justin T. Rogers, Zachary Quicksall, Cynthia Linares, Joshua A. Knight, Yixing Chen, Aishe Kurti, Takahisa Kanekiyo, John Denis Fryer, Yan W. Asmann, Peter Störz, Xusheng Wang, Junmin Peng, Bin Zhang, Betty Y.S. Kim, Guojun Bu

    出版 2022
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  20. 20
    <i>APOE3</i> -Jacksonville (V236E) variant reduces self-aggregation and risk of dementia

    <i>APOE3</i> -Jacksonville (V236E) variant reduces self-aggregation and risk of dementia 由 Chia‐Chen Liu, Melissa E. Murray, Xia Li, Na Zhao, Na Wang, Michael G. Heckman, Francis Shue, Yuka A. Martens, Yonghe Li, Ana‐Caroline Raulin, Cassandra L. Rosenberg, Sydney V. Doss, Jing Zhao, Melissa C. Wren, Lin Jia, Yingxue Ren, Tadafumi C. Ikezu, Wenyan Lü, Yuan Fu, Thomas R. Caulfield, Zachary A. Trottier, Joshua A. Knight, Yixing Chen, Cynthia Linares, Xue Wang, Aishe Kurti, Yan W. Asmann, Zbigniew K. Wszołek, Glenn E. Smith, Prashanthi Vemuri, Kejal Kantarci, David S. Knopman, Val J. Lowe, Clifford R. Jack, Joseph E. Parisi, Tanis J. Ferman, Bradley F. Boeve, Neill R. Graff‐Radford, Ronald C. Petersen, Steven G. Younkin, John Denis Fryer, Hu Wang, Xianlin Han, Carl Frieden, Dennis W. Dickson, Owen A. Ross, Guojun Bu

    出版 2021
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