檢索結果 - Yingleong Chan

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  1. 1
    Synthesizing genome-wide association studies and expression microarray reveals novel genes that act in the human growth plate to modulate height

    Synthesizing genome-wide association studies and expression microarray reveals novel genes that act in the human growth plate to modulate height 由 Julian C. Lui, Ola Nilsson, Yingleong Chan, Cameron D. Palmer, Anenisia C. Andrade, Joel N. Hirschhorn, Jeffrey Baron

    出版 2012
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  2. 2
    An Excess of Risk-Increasing Low-Frequency Variants Can Be a Signal of Polygenic Inheritance in Complex Diseases

    An Excess of Risk-Increasing Low-Frequency Variants Can Be a Signal of Polygenic Inheritance in Complex Diseases 由 Yingleong Chan, Elaine T. Lim, Niina Sandholm, Sophie R. Wang, Amy Jayne McKnight, Stephan Ripke, Mark J. Daly, Benjamin M. Neale, Rany M. Salem, Joel N. Hirschhorn

    出版 2014
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  3. 3
    High-throughput creation and functional profiling of DNA sequence variant libraries using CRISPR–Cas9 in yeast

    High-throughput creation and functional profiling of DNA sequence variant libraries using CRISPR–Cas9 in yeast 由 Xiaoge Guo, Alejandro Chavez, Angela Tung, Yingleong Chan, Christian S. Kaas, Yi Yin, Ryan J. Cecchi, Santiago C. Lopez, Eric D. Kelsic, Max G. Schubert, James J. DiCarlo, James J. Collins, George M. Church

    出版 2018
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  4. 4
    Genome-wide Analysis of Body Proportion Classifies Height-Associated Variants by Mechanism of Action and Implicates Genes Important for Skeletal Development

    Genome-wide Analysis of Body Proportion Classifies Height-Associated Variants by Mechanism of Action and Implicates Genes Important for Skeletal Development 由 Yingleong Chan, Rany M. Salem, Yu-Han H. Hsu, George McMahon, Tune H. Pers, Sailaja Vedantam, Tõnu Esko, Michael H. Guo, Elaine T. Lim, Lude Franke, George Davey Smith, David P. Strachan, Joel N. Hirschhorn

    出版 2015
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  5. 5
    Common Variants Show Predicted Polygenic Effects on Height in the Tails of the Distribution, Except in Extremely Short Individuals

    Common Variants Show Predicted Polygenic Effects on Height in the Tails of the Distribution, Except in Extremely Short Individuals 由 Yingleong Chan, Oddgeir L. Holmen, Andrew Dauber, Lars J. Vatten, Aki S. Havulinna, Frank Skorpen, Kirsti Kvaløy, Kaisa Silander, Thutrang Nguyen, Cristen J. Willer, Michael Boehnke, Markus Perola, Aarno Palotie, Veikko Salomaa, Kristian Hveem, Timothy M. Frayling, Joel N. Hirschhorn, Michael N. Weedon

    出版 2011
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  6. 6
    Biological interpretation of genome-wide association studies using predicted gene functions

    Biological interpretation of genome-wide association studies using predicted gene functions 由 Tune H. Pers, Juha Karjalainen, Yingleong Chan, Harm-Jan Westra, Andrew R. Wood, Jian Yang, Julian C. Lui, Sailaja Vedantam, Stefan Gustafsson, Tõnu Esko, Timothy M. Frayling, Elizabeth K. Speliotes, Michael Boehnke, Soumya Raychaudhuri, Rudolf S.N. Fehrmann, Joel N. Hirschhorn, Lude Franke

    出版 2015
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  7. 7
    An enhanced CRISPR repressor for targeted mammalian gene regulation

    An enhanced CRISPR repressor for targeted mammalian gene regulation 由 Nan Cher Yeo, Alejandro Chavez, Alissa Lance‐Byrne, Yingleong Chan, David J Menn, Denitsa Milanova, Chih-Chung Kuo, Xiaoge Guo, Sumana Sharma, Angela Tung, Ryan J. Cecchi, Marcelle Tuttle, Swechchha Pradhan, Elaine T. Lim, Noah Davidsohn, Mo R. Ebrahimkhani, James J. Collins, Nathan E. Lewis, Samira Kiani, George M. Church

    出版 2018
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  8. 8
    Rates, distribution and implications of postzygotic mosaic mutations in autism spectrum disorder

    Rates, distribution and implications of postzygotic mosaic mutations in autism spectrum disorder 由 Elaine T. Lim, Mohammed Uddin, Silvia De Rubeis, Yingleong Chan, A. Stacy Kamumbu, Xiaochang Zhang, Alissa M. D’Gama, Sonia N. Kim, Robert Hill, Arthur P. Goldberg, Christopher S. Poultney, Nancy J. Minshew, Itaru Kushima, Branko Aleksić, Norio Ozaki, Mara Parellada, Celso Arango, María José Penzol, Ángel Carracedo, Alexander Kolevzon, Christina M. Hultman, Lauren A. Weiss, Menachem Fromer, Andreas G. Chiocchetti, Christine M. Freitag, George M. Church, Stephen W. Scherer, Joseph D. Buxbaum, Christopher A. Walsh

    出版 2017
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  9. 9
    Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses

    Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses 由 Ying Kai Chan, Sean K. Wang, Colin J. Chu, David A. Copland, Alexander J. Letizia, Helena Costa Verdera, Jessica J. Chiang, Meher Sethi, May K. Wang, William J. Neidermyer, Yingleong Chan, Elaine T. Lim, Amanda Graveline, Melinda Sanchez, Ryan F. Boyd, Thomas S. Vihtelic, Rolando Gian Carlo O. Inciong, Jared M. Slain, Priscilla J. Alphonse, Yunlu Xue, Lindsey R. Robinson‐McCarthy, Jenny M. Tam, Maha Jabbar, Bhubanananda Sahu, Janelle Fassbender Adeniran, Manish Muhuri, Phillip W.L. Tai, Jun Xie, Tyler B. Krause, Andyna Vernet, Matthew J. Pezone, Ru Xiao, Tina Liu, Wei Wang, Henry J. Kaplan, Guangping Gao, Andrew D. Dick, Federico Mingozzi, Maureen A. McCall, Constance L. Cepko, George M. Church

    出版 2021
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  10. 10
    Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population

    Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population 由 Elaine T. Lim, Peter Würtz, Aki S. Havulinna, Priit Palta, Taru Tukiainen, Karola Rehnström, Tõnu Esko, Reedik Mägi, Michael Inouye, Tuuli Lappalainen, Yingleong Chan, Rany M. Salem, Monkol Lek, Jason Flannick, Xueling Sim, Alisa K. Manning, Claes Ladenvall, Suzannah Bumpstead, Eija Hämäläinen, Kristiina Aalto, Mikael Maksimow, Marko Salmi, Stefan Blankenberg, Diego Ardissino, Svati H. Shah, Benjamin D. Horne, Ruth McPherson, Gerald K. Hovingh, Muredach P. Reilly, Hugh Watkins, Anuj Goel, Martin Farrall, Domenico Girelli, Alex P. Reiner, Nathan O. Stitziel, Sekar Kathiresan, Stacey Gabriel, Jeffrey C. Barrett, Terho Lehtimäki, Markku Laakso, Leif Groop, Jaakko Kaprio, Markus Perola, Mark I. McCarthy, Michael Boehnke, David Altshuler, Cecilia M. Lindgren, Joel N. Hirschhorn, Andres Metspalu, Nelson B. Freimer, Tanja Zeller, Sirpa Jalkanen, Seppo Koskinen, Olli T. Raitakari, Richard Durbin, Daniel G. MacArthur, Veikko Salomaa, Samuli Ripatti, Mark J. Daly, Aarno Palotie

    出版 2014
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  11. 11
    Directional dominance on stature and cognition in diverse human populations

    Directional dominance on stature and cognition in diverse human populations 由 Peter K. Joshi, Tõnu Esko, Hannele Mattsson, Niina Eklund, Ilaria Gandin, Teresa Nutile, Anne Jackson, Claudia Schurmann, Albert V. Smith, Weihua Zhang, Yukinori Okada, Alena Stančáková, Jessica D. Faul, Wei Zhao, Traci M. Bartz, Maria Pina Concas, Nora Franceschini, Stefan Enroth, Véronique Vitart, Stella Trompet, Xiuqing Guo, Daniel I. Chasman, Jeffrey R. O’Connel, Tanguy Corre, Suraj S. Nongmaithem, Yuning Chen, Massimo Mangino, Daniela Ruggiero, Michela Traglia, Aliki‐Eleni Farmaki, Tim Kacprowski, Andrew Bjonnes, Ashley van der Spek, Ying Wu, Anil K. Giri, Lisa R. Yanek, Lihua Wang, Edith Hofer, Cornelius A. Rietveld, Olga McLeod, Marilyn C. Cornelis, Cristian Pattaro, Niek Verweij, Clemens Baumbach, Abdel Abdellaoui, Helen R. Warren, Dragana Vuckovic, Hao Mei, Claude Bouchard, John R. B. Perry, Stefania Cappellani, Saira Saeed Mirza, Miles C. Benton, Ulrich Broeckel, Sarah E. Medland, Penelope A. Lind, Giovanni Malerba, Alexander Drong, Loïc Yengo, Lawrence F. Bielak, Degui Zhi, Peter J. van der Most, Daniel Shriner, Reedik Mägi, Gibran Hemani, Tugce Karaderi, Thomas J. Wang, Tian Liu, Ilja Demuth, Jing Hua Zhao, Weihua Meng, Lazaros Lataniotis, Sander W. van der Laan, Jonathan P. Bradfield, Andrew R. Wood, Amélie Bonnefond, Tarunveer S. Ahluwalia, Leanne M. Hall, Erika Salvi, Seyhan Yazar, Lisbeth Carstensen, Hugoline G. de Haan, Mark Abney, Uzma Afzal, Matthew Allison, Najaf Amin, Folkert W. Asselbergs, Stephan J. L. Bakker, R. Graham Barr, Sebastian E. Baumeister, Daniel J. Benjamin, Sven Bergmann, Eric Boerwinkle, Erwin P. Böttinger, Archie Campbell, Aravinda Chakravarti, Yingleong Chan, Stephen J. Chanock, Constance Chen, Y.-D. Ida Chen

    出版 2015
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