Suchergebnisse - Xinhui Chen

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  1. 1
    Deciphering Immunometabolic Landscape in Rheumatoid Arthritis: Integrative Multiomics, Explainable Machine Learning and Experimental Validation

    Deciphering Immunometabolic Landscape in Rheumatoid Arthritis: Integrative Multiomics, Explainable Machine Learning and Experimental Validation von Qiu Dong, Jiayang Wu, Huaguo Zhang, Xinhui Chen, Xi Xu, Jifeng Chen, Changzheng Shi, Liangping Luo, Dong Zhang

    Veröffentlicht 2025
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  2. 2
    E3 ligase ZFP91 inhibits Hepatocellular Carcinoma Metabolism Reprogramming by regulating PKM splicing

    E3 ligase ZFP91 inhibits Hepatocellular Carcinoma Metabolism Reprogramming by regulating PKM splicing von De Chen, Yanjie Wang, Ruixun Lu, Xiaofeng Jiang, Xinhui Chen, Nan Meng, Min Chen, Shan Xie, Guang‐Rong Yan

    Veröffentlicht 2020
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  3. 3
    An oncopeptide regulates m6A recognition by the m6A reader IGF2BP1 and tumorigenesis

    An oncopeptide regulates m6A recognition by the m6A reader IGF2BP1 and tumorigenesis von Song Zhu, Jizhong Wang, De Chen, Yutian He, Nan Meng, Min Chen, Ruixun Lu, Xinhui Chen, Xiaolan Zhang, Guang‐Rong Yan

    Veröffentlicht 2020
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  4. 4
    K235 acetylation couples with PSPC1 to regulate the m6A demethylation activity of ALKBH5 and tumorigenesis

    K235 acetylation couples with PSPC1 to regulate the m6A demethylation activity of ALKBH5 and tumorigenesis von Xiaolan Zhang, Xinhui Chen, Binwu Xu, Min Chen, Song Zhu, Nan Meng, Jizhong Wang, Hui‐Fang Zhu, De Chen, Jinbao Liu, Guang‐Rong Yan

    Veröffentlicht 2023
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  5. 5
    Long-read sequencing revealed complex biallelic pentanucleotide repeat expansions in RFC1-related Parkinson’s disease

    Long-read sequencing revealed complex biallelic pentanucleotide repeat expansions in RFC1-related Parkinson’s disease von Peng Liu, Fan Zhang, Xinhui Chen, Xiaosheng Zheng, Miao Chen, Zhiru Lin, Shuqi Chen, Lebo Wang, Xinchen Wang, Nan Jin, Chenxin Ying, Fei Xie, Bo Wang, Sheng Wu, Zhidong Cen, Wei Luo

    Veröffentlicht 2025
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  6. 6
    First-in-human phase I/Ib open-label dose-escalation study of GWN323 (anti-GITR) as a single agent and in combination with spartalizumab (anti-PD-1) in patients with advanced solid tumors and lymphomas

    First-in-human phase I/Ib open-label dose-escalation study of GWN323 (anti-GITR) as a single agent and in combination with spartalizumab (anti-PD-1) in patients with advanced solid... von Sarina A. Piha‐Paul, Ravit Geva, Tira J. Tan, Wan‐Teck Lim, Cinta Hierro, Toshikiko Doi, Osama E. Rahma, Alexander M. Lesokhin, Jason J. Luke, J. Otero, Lisa Nardi, Angad Singh, Alexandros Xyrafas, Xinhui Chen, Jennifer Mataraza, Philippe L. Bédard

    Veröffentlicht 2021
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  7. 7
    Phase I Dose-Escalation Trial of MIW815 (ADU-S100), an Intratumoral STING Agonist, in Patients with Advanced/Metastatic Solid Tumors or Lymphomas

    Phase I Dose-Escalation Trial of MIW815 (ADU-S100), an Intratumoral STING Agonist, in Patients with Advanced/Metastatic Solid Tumors or Lymphomas von Funda Meric‐Bernstam, Randy F. Sweis, F. Stephen Hodi, Wells A. Messersmith, Robert H.I. Andtbacka, Matthew Ingham, Nancy Lewis, Xinhui Chen, Marc R. Pelletier, Xueying Chen, Jincheng Wu, Thomas W. Dubensky, Sarah M. McWhirter, Thomas Müller, Nitya Nair, Jason J. Luke

    Veröffentlicht 2021
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  8. 8
    Combination of the STING Agonist MIW815 (ADU-S100) and PD-1 Inhibitor Spartalizumab in Advanced/Metastatic Solid Tumors or Lymphomas: An Open-Label, Multicenter, Phase Ib Study

    Combination of the STING Agonist MIW815 (ADU-S100) and PD-1 Inhibitor Spartalizumab in Advanced/Metastatic Solid Tumors or Lymphomas: An Open-Label, Multicenter, Phase Ib Study von Funda Meric‐Bernstam, Randy F. Sweis, Stefan Kasper, Omid Hamid, Shailender Bhatia, Reinhard Dummer, Agostina Stradella, Georgina V. Long, Anna Spreafico, Toshio Shimizu, Neeltje Steeghs, Jason J. Luke, Sarah M. McWhirter, Thomas Müller, Nitya Nair, Nancy Lewis, Xinhui Chen, Andrew Bean, Lisa Kattenhorn, Marc R. Pelletier, Shahneen Sandhu

    Veröffentlicht 2022
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  9. 9
    SLC7A11 is an unconventional H+ transporter in lysosomes

    SLC7A11 is an unconventional H+ transporter in lysosomes von Nan Zhou, Jingzhi Chen, Meiqin Hu, Na Wen, Weijie Cai, Ping Li, Liding Zhao, Yaping Meng, Zhao Dongdong, Xiaotong Yang, Siyu Liu, Fangqian Huang, Cheng Zhao, Xinghua Feng, Zikai Jiang, Enjun Xie, Hongxu Pan, Zhidong Cen, Xinhui Chen, Wei Luo, Beisha Tang, Junxia Min, Fudi Wang, Junsheng Yang, Haoxing Xu

    Veröffentlicht 2025
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  10. 10
    Intracellular Tenofovir and Emtricitabine Anabolites in Genital, Rectal, and Blood Compartments from First Dose to Steady State

    Intracellular Tenofovir and Emtricitabine Anabolites in Genital, Rectal, and Blood Compartments from First Dose to Steady State von Sharon M. Seifert, Xinhui Chen, Amie L. Meditz, José Castillo‐Mancilla, Edward M. Gardner, Julie A. Predhomme, Carolyn Clayton, Gregory L. Austin, Brent E. Palmer, Jia‐Hua Zheng, Brandon Klein, Becky Jo Kerr, Louis Guida, Caitlin Rower, Joseph E. Rower, Jennifer J. Kiser, Lane R. Bushman, Samantha MaWhinney, Peter L. Anderson

    Veröffentlicht 2016
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  11. 11
    Biallelic loss-of-function mutations in JAM2 cause primary familial brain calcification

    Biallelic loss-of-function mutations in JAM2 cause primary familial brain calcification von Zhidong Cen, You Chen, Si Chen, Hong Wang, Dehao Yang, Hongmei Zhang, Hongwei Wu, Lebo Wang, Siyang Tang, Jia Ye, Jian Shen, Haotian Wang, Feng Fu, Xinhui Chen, Fei Xie, Peng Liu, Xuan Xu, Jianzhi Cao, Pan Cai, Qinqing Pan, Jieying Li, Wei Yang, Peng‐Fei Shan, Yuezhou Li, Jingyu Liu, Baorong Zhang, Wei Luo

    Veröffentlicht 2019
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