Search Results - Xin‐Yan Pei

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  1. 1
    Bim Upregulation by Histone Deacetylase Inhibitors Mediates Interactions with the Bcl-2 Antagonist ABT-737: Evidence for Distinct Roles for Bcl-2, Bcl-x<sub>L</sub>, and Mcl-1

    Bim Upregulation by Histone Deacetylase Inhibitors Mediates Interactions with the Bcl-2 Antagonist ABT-737: Evidence for Distinct Roles for Bcl-2, Bcl-x<sub>L</sub>, and Mcl-1 by Shuang Chen, Yun Dai, Xin‐Yan Pei, Steven Grant

    Published 2009
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  2. 2
    Bortezomib and flavopiridol interact synergistically to induce apoptosis in chronic myeloid leukemia cells resistant to imatinib mesylate through both Bcr/Abl-dependent and -independent mechanisms

    Bortezomib and flavopiridol interact synergistically to induce apoptosis in chronic myeloid leukemia cells resistant to imatinib mesylate through both Bcr/Abl-dependent and -indepe... by Yun Dai, Mohamed Rahmani, Xin‐Yan Pei, Paul Dent, Steven Grant

    Published 2004
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  3. 3
    Statins synergistically potentiate 7-hydroxystaurosporine (UCN-01) lethality in human leukemia and myeloma cells by disrupting Ras farnesylation and activation

    Statins synergistically potentiate 7-hydroxystaurosporine (UCN-01) lethality in human leukemia and myeloma cells by disrupting Ras farnesylation and activation by Yun Dai, Payal Khanna, Shuang Chen, Xin‐Yan Pei, Paul Dent, Steven Grant

    Published 2007
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  4. 4
    Interruption of the NF-κB pathway by Bay 11-7082 promotes UCN-01-mediated mitochondrial dysfunction and apoptosis in human multiple myeloma cells

    Interruption of the NF-κB pathway by Bay 11-7082 promotes UCN-01-mediated mitochondrial dysfunction and apoptosis in human multiple myeloma cells by Yun Dai, Xin‐Yan Pei, Mohamed Rahmani, Daniel H. Conrad, Paul Dent, Steven Grant

    Published 2003
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  5. 5
    Bortezomib interacts synergistically with belinostat in human acute myeloid leukaemia and acute lymphoblastic leukaemia cells in association with perturbations in NF‐κB and Bim

    Bortezomib interacts synergistically with belinostat in human acute myeloid leukaemia and acute lymphoblastic leukaemia cells in association with perturbations in NF‐κB and Bim by Yun Dai, Shuang Chen, Li Wang, Xin-Yan Pei, Lora B. Kramer, Paul Dent, Steven Grant

    Published 2011
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  6. 6
    The Novel Chk1 Inhibitor MK-8776 Sensitizes Human Leukemia Cells to HDAC Inhibitors by Targeting the Intra-S Checkpoint and DNA Replication and Repair

    The Novel Chk1 Inhibitor MK-8776 Sensitizes Human Leukemia Cells to HDAC Inhibitors by Targeting the Intra-S Checkpoint and DNA Replication and Repair by Yun Dai, Shuang Chen, Maciej Kmieciak, Liang Zhou, Hui‐Yi Lin, Xin‐Yan Pei, Steven Grant

    Published 2013
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  7. 7
    Vorinostat synergistically potentiates MK-0457 lethality in chronic myelogenous leukemia cells sensitive and resistant to imatinib mesylate

    Vorinostat synergistically potentiates MK-0457 lethality in chronic myelogenous leukemia cells sensitive and resistant to imatinib mesylate by Yun Dai, Shuang Chen, Charis A. Venditti, Xin‐Yan Pei, Tri K. Nguyen, Paul Dent, Steven Grant

    Published 2008
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  8. 8
    Interruption of the Ras/MEK/ERK signaling cascade enhances Chk1 inhibitor–induced DNA damage in vitro and in vivo in human multiple myeloma cells

    Interruption of the Ras/MEK/ERK signaling cascade enhances Chk1 inhibitor–induced DNA damage in vitro and in vivo in human multiple myeloma cells by Yun Dai, Shuang Chen, Xin‐Yan Pei, Jorge A. Almenara, Lora B. Kramer, Charis A. Venditti, Paul Dent, Steven Grant

    Published 2008
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  9. 9
    The NF (Nuclear factor)‐κB inhibitor parthenolide interacts with histone deacetylase inhibitors to induce MKK7/JNK1‐dependent apoptosis in human acute myeloid leukaemia cells

    The NF (Nuclear factor)‐κB inhibitor parthenolide interacts with histone deacetylase inhibitors to induce MKK7/JNK1‐dependent apoptosis in human acute myeloid leukaemia cells by Yun Dai, Mónica L. Guzmán, Shuang Chen, Li Wang, Sin‐Kei Yeung, Xin‐Yan Pei, Paul Dent, Craig T. Jordan, Steven Grant

    Published 2010
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  10. 10
    Targeting SQSTM1/p62 Induces Cargo Loading Failure and Converts Autophagy to Apoptosis via NBK/Bik

    Targeting SQSTM1/p62 Induces Cargo Loading Failure and Converts Autophagy to Apoptosis via NBK/Bik by Shuang Chen, Liang Zhou, Yu Zhang, Yun Leng, Xin-Yan Pei, Hui‐Yi Lin, Richard Jones, Robert Z. Orlowski, Yun Dai, Steven Grant

    Published 2014
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  11. 11
    Cotargeting BCL-2 and PI3K Induces BAX-Dependent Mitochondrial Apoptosis in AML Cells

    Cotargeting BCL-2 and PI3K Induces BAX-Dependent Mitochondrial Apoptosis in AML Cells by Mohamed Rahmani, Jewel Nkwocha, Elisa Hawkins, Xin‐Yan Pei, Rebecca E. Parker, Maciej Kmieciak, Joel D. Leverson, Deepak Sampath, Andrea Ferreira‐Gonzalez, Steven Grant

    Published 2018
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  12. 12
    A Bim-targeting strategy overcomes adaptive bortezomib resistance in myeloma through a novel link between autophagy and apoptosis

    A Bim-targeting strategy overcomes adaptive bortezomib resistance in myeloma through a novel link between autophagy and apoptosis by Shuang Chen, Yu Zhang, Liang Zhou, Yun Leng, Hui‐Yi Lin, Maciej Kmieciak, Xin-Yan Pei, Richard Jones, Robert Z. Orlowski, Yun Dai, Steven Grant

    Published 2014
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  13. 13
    CDK Inhibitors Upregulate BH3-Only Proteins to Sensitize Human Myeloma Cells to BH3 Mimetic Therapies

    CDK Inhibitors Upregulate BH3-Only Proteins to Sensitize Human Myeloma Cells to BH3 Mimetic Therapies by Shuang Chen, Yun Dai, Xin-Yan Pei, Jennifer L. Myers, Li Wang, Lora B. Kramer, Mandy Garnett, Daniella M. Schwartz, Florence Su, Gary Simmons, Justin D. Richey, Dustin G. Larsen, Paul Dent, Robert Z. Orlowski, Steven Grant

    Published 2012
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