檢索結果 - Xikun Han

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  1. 1
    The effects of eight serum lipid biomarkers on age-related macular degeneration risk: a Mendelian randomization study

    The effects of eight serum lipid biomarkers on age-related macular degeneration risk: a Mendelian randomization study 由 Xikun Han, Jue‐Sheng Ong, Alex W. Hewitt, Puya Gharahkhani, Stuart MacGregor

    出版 2020
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  2. 2
    Genome-Wide Meta-analysis Identifies Risk Loci and Improves Disease Prediction of Age-Related Macular Degeneration

    Genome-Wide Meta-analysis Identifies Risk Loci and Improves Disease Prediction of Age-Related Macular Degeneration 由 Weixiong He, Xikun Han, Jue‐Sheng Ong, Yeda Wu, Alex W. Hewitt, David A. Mackey, Puya Gharahkhani, Stuart MacGregor

    出版 2023
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  3. 3
    Combined analysis of keratinocyte cancers identifies novel genome-wide loci

    Combined analysis of keratinocyte cancers identifies novel genome-wide loci 由 Upekha E. Liyanage, Matthew H. Law, Xikun Han, Jiyuan An, Jue‐Sheng Ong, Puya Gharahkhani, Scott D. Gordon, Rachel Ε. Neale, Catherine M. Olsen, Stuart MacGregor, David C. Whiteman

    出版 2019
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  4. 4
    Automated AI labeling of optic nerve head enables insights into cross-ancestry glaucoma risk and genetic discovery in >280,000 images from UKB and CLSA

    Automated AI labeling of optic nerve head enables insights into cross-ancestry glaucoma risk and genetic discovery in >280,000 images from UKB and CLSA 由 Xikun Han, Kaiah Steven, Ayub Qassim, Henry Marshall, Cameron Bean, Michael Tremeer, Jiyuan An, Owen M. Siggs, Puya Gharahkhani, Jamie E. Craig, Alex W. Hewitt, Maciej Trzaskowski, Stuart MacGregor

    出版 2021
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  5. 5
    The low-dose colchicine in patients after non-CABG cardiac surgery: a randomized controlled trial

    The low-dose colchicine in patients after non-CABG cardiac surgery: a randomized controlled trial 由 Tuo Pan, Chenyu Jiang, He Zhang, Xikun Han, Haitao Zhang, Xinyi Jiang, Wei Chen, Kuo Wang, Fu-Dong Fan, Jun Pan, Qing Zhou, Chuangshi Wang, Li Zhang, Dongjin Wang

    出版 2023
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  6. 6
    Multitrait genetic association analysis identifies 50 new risk loci for gastro-oesophageal reflux, seven new loci for Barrett’s oesophagus and provides insights into clinical heterogeneity in reflux diagnosis

    Multitrait genetic association analysis identifies 50 new risk loci for gastro-oesophageal reflux, seven new loci for Barrett’s oesophagus and provides insights into clinical heter... 由 Jue‐Sheng Ong, Jiyuan An, Xikun Han, Matthew H. Law, Priyanka Nandakumar, Johannes Schumacher, Ines Gockel, Anne C. Böhmer, Janusz Jankowski, Claire Palles, Catherine M. Olsen, Rachel Ε. Neale, Rebecca C. Fitzgerald, Aaron P. Thrift, Thomas L. Vaughan, Matthew F. Buas, David A Hinds, Puya Gharahkhani, Bradley J. Kendall, Stuart MacGregor

    出版 2021
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  7. 7
    Myocilin Gene Gln368Ter Variant Penetrance and Association With Glaucoma in Population-Based and Registry-Based Studies

    Myocilin Gene Gln368Ter Variant Penetrance and Association With Glaucoma in Population-Based and Registry-Based Studies 由 Xikun Han, Emmanuelle Souzeau, Jue‐Sheng Ong, Jiyuan An, Owen M. Siggs, Kathryn P. Burdon, Stephen Best, Ivan Goldberg, Paul R. Healey, Stuart L. Graham, Jonathan B. Ruddle, Richard Mills, John Landers, Anna Galanopoulos, Andrew White, Robert J. Casson, David A. Mackey, Alex W. Hewitt, Puya Gharahkhani, Jamie E. Craig, Stuart MacGregor

    出版 2018
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  8. 8
    An Intraocular Pressure Polygenic Risk Score Stratifies Multiple Primary Open-Angle Glaucoma Parameters Including Treatment Intensity

    An Intraocular Pressure Polygenic Risk Score Stratifies Multiple Primary Open-Angle Glaucoma Parameters Including Treatment Intensity 由 Ayub Qassim, Emmanuelle Souzeau, Owen M. Siggs, Mark Hassall, Xikun Han, Helen Griffiths, N A Frost, Neeru A. Vallabh, James Kirwan, Geeta Menon, Angela J. Cree, Anna Galanopoulos, Ashish Agar, Paul R. Healey, Stuart L. Graham, John Landers, Robert J. Casson, Puya Gharahkhani, Colin E. Willoughby, Alex W. Hewitt, Andrew Lotery, Stuart MacGregor, Jamie E. Craig

    出版 2020
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  9. 9
    Transcriptomic and proteomic retinal pigment epithelium signatures of age-related macular degeneration

    Transcriptomic and proteomic retinal pigment epithelium signatures of age-related macular degeneration 由 Anne Senabouth, Maciej Daniszewski, Grace E. Lidgerwood, Helena Liang, Damián Hernández, Mehdi Mirzaei, Stacey N. Keenan, Ran Zhang, Xikun Han, Drew Neavin, Louise Rooney, M. Isabel G. Lopez Sanchez, Lerna Gulluyan, João A. Paulo, Linda Clarke, Lisa S. Kearns, Vikkitharan Gnanasambandapillai, Chia‐Ling Chan, Uyen Nguyen, Angela Steinmann, Rachael A. McCloy, Nona Farbehi, Vivek Gupta, David A. Mackey, Guy Bylsma, Nitin Verma, Stuart MacGregor, Matthew J. Watt, Robyn H. Guymer, Joseph E. Powell, Alex W. Hewitt, Alice Pébay

    出版 2022
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  10. 10
    Large-scale multitrait genome-wide association analyses identify hundreds of glaucoma risk loci

    Large-scale multitrait genome-wide association analyses identify hundreds of glaucoma risk loci 由 Xikun Han, Puya Gharahkhani, Andrew R. Hamel, Jue‐Sheng Ong, Miguel E. Rentería, Puja A. Mehta, Xianjun Dong, Francesca Pasutto, Christopher J. Hammond, Terri L. Young, Pirro G. Hysi, Andrew Lotery, Eric Jorgenson, Hélène Choquet, Michael A. Hauser, Jessica N. Cooke Bailey, Toru Nakazawa, Masato Akiyama, Yukihiro Shiga, Zachary L. Fuller, Xin Wang, Alex W. Hewitt, Jamie E. Craig, Louis R. Pasquale, David A. Mackey, Janey L. Wiggs, Anthony P. Khawaja, Ayellet V. Segrè, Stuart MacGregor

    出版 2023
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  11. 11
    Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma

    Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma 由 Stuart MacGregor, Jue‐Sheng Ong, Jiyuan An, Xikun Han, Tiger Zhou, Owen M. Siggs, Matthew H. Law, Emmanuelle Souzeau, Shiwani Sharma, David J. Lynn, Jonathan Beesley, Bronwyn Sheldrick, Richard Mills, John Landers, Jonathan B. Ruddle, Stuart L. Graham, Paul R. Healey, Andrew White, Robert J. Casson, Stephen Best, John Grigg, Ivan Goldberg, Joseph E. Powell, David C. Whiteman, Graham Radford‐Smith, Nicholas G. Martin, Grant W. Montgomery, Kathryn P. Burdon, David A. Mackey, Puya Gharahkhani, Jamie E. Craig, Alex W. Hewitt

    出版 2018
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  12. 12
    Integrating genetics and metabolomics from multi-ethnic and multi-fluid data reveals putative mechanisms for age-related macular degeneration

    Integrating genetics and metabolomics from multi-ethnic and multi-fluid data reveals putative mechanisms for age-related macular degeneration 由 Xikun Han, Inês Laíns, Jun Li, Jinglun Li, Yiheng Chen, Bing Yu, Qibin Qi, Eric Boerwinkle, Robert C. Kaplan, Bharat Thyagarajan, Martha L. Daviglus, Charlotte E. Joslin, Jianwen Cai, Marta Guasch‐Ferré, Deirdre K. Tobias, Eric B. Rimm, Alberto Ascherio, Karen H. Costenbader, Elizabeth W. Karlson, Lorelei A. Mucci, A. Heather Eliassen, Oana A. Zeleznik, John B. Miller, Demetrios G. Vavvas, Ivana K. Kim, Rufino Silva, Joan W. Miller, Frank B. Hu, Walter C. Willett, Jessica Lasky‐Su, Peter Kraft, J. Brent Richards, Stuart MacGregor, Deeba Husain, Liming Liang

    出版 2023
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  13. 13
    Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases

    Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases 由 Jiyuan An, Puya Gharahkhani, Matthew H. Law, Jue‐Sheng Ong, Xikun Han, Catherine M. Olsen, Rachel Ε. Neale, John Lai, Tom L. Vaughan, Ines Gockel, René Thieme, Anne C. Böhmer, Janusz Jankowski, Rebecca C. Fitzgerald, Johannes Schumacher, Claire Palles, Marilie D. Gammon, Douglas A. Corley, Nicholas J. Shaheen, Nigel C. Bird, Laura J. Hardie, Liam Murray, Brian J. Reid, Wong‐Ho Chow, Harvey A. Risch, Weimin Ye, Geoffrey Liu, Yvonne Romero, Leslie Bernstein, Anna H. Wu, Michelle Agee, Babak Alipanahi, A. Auton, R. K. Bell, Katarzyna Bryc, Sarah L. Elson, Pierre Fontanillas, Nicholas A. Furlotte, D. A. Hinds, Karen E. Huber, Aaron Kleinman, Nadia K. Litterman, M. H. McIntyre, Joanna L. Mountain, Elizabeth S. Noblin, Carrie A. M. Northover, Steven J. Pitts, J. Fah Sathirapongsasuti, Olga V. Sazonova, Janie F. Shelton, Suyash Shringarpure, C Tian, Joyce Y. Tung, Vladimir Vacic, Catherine H. Wilson, David C. Whiteman, Stuart MacGregor

    出版 2019
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  14. 14
    Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression

    Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression 由 Jamie E. Craig, Xikun Han, Ayub Qassim, Mark Hassall, Jessica N. Cooke Bailey, Tyler G. Kinzy, Anthony P. Khawaja, Jiyuan An, Henry Marshall, Puya Gharahkhani, Robert P. Igo, Stuart L. Graham, Paul R. Healey, Jue‐Sheng Ong, Tiger Zhou, Owen M. Siggs, Matthew H. Law, Emmanuelle Souzeau, Bronwyn Ridge, Pirro G. Hysi, Kathryn P. Burdon, Richard Mills, John Landers, Jonathan B. Ruddle, Ashish Agar, Anna Galanopoulos, Andrew White, Colin E. Willoughby, Nicholas H. Andrew, Stephen Best, Andrea L. Vincent, Ivan Goldberg, Graham Radford‐Smith, Nicholas G. Martin, Grant W. Montgomery, Véronique Vitart, René Hoehn, Robert Wojciechowski, Jost B. Jonas, Tin Aung, Louis R. Pasquale, Angela J. Cree, Sobha Sivaprasad, Neeru A. Vallabh, Ananth C. Viswanathan, Francesca Pasutto, Jonathan L. Haines, Caroline C. W. Klaver, Cornelia M. van Duijn, Robert J. Casson, Paul J. Foster, Peng T. Khaw, Christopher J. Hammond, David A. Mackey, Paul Mitchell, Andrew Lotery, Janey L. Wiggs, Alex W. Hewitt, Stuart MacGregor

    出版 2020
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  15. 15
    A comprehensive re-assessment of the association between vitamin D and cancer susceptibility using Mendelian randomization

    A comprehensive re-assessment of the association between vitamin D and cancer susceptibility using Mendelian randomization 由 Jue‐Sheng Ong, Suzanne C. Dixon‐Suen, Xikun Han, Jiyuan An, Rebecca C. Fitzgerald, Matt Buas, Marilie D. Gammon, Douglas A. Corley, Nicholas J. Shaheen, Laura J. Hardie, Nigel C. Bird, Brian J. Reid, Wong‐Ho Chow, Harvey A. Risch, Weimin Ye, Geoffrey Liu, Yvonne Romero, Leslie Bernstein, Anna H. Wu, David E. Whiteman, Thomas E. Vaughan, Michelle Agee, Babak Alipanahi, A. Auton, R. K. Bell, Katarzyna Bryc, Sarah L. Elson, Pierre Fontanillas, Nicholas A. Furlotte, D. A. Hinds, Karen E. Huber, Aaron Kleinman, Nadia K. Litterman, M. H. McIntyre, J. L. Mountain, Elizabeth S. Noblin, Carrie A. M. Northover, Steven J. Pitts, J. Fah Sathirapongsasuti, Olga V. Sazonova, Janie F. Shelton, Suyash Shringarpure, C Tian, Joyce Y. Tung, Vladimir Vacic, Catherine H. Wilson, Upekha E. Liyanage, Jean-Cluade Dusingize, Johannes Schumacher, Ines Gockel, Anne C. Böhmer, Janusz Jankowski, Claire Palles, Tracy A. O’Mara, Amanda B. Spurdle, Matthew H. Law, Mark M. Iles, Paul D.P. Pharoah, Andrew Berchuck, Wei Zheng, Aaron P. Thrift, Catherine M. Olsen, Rachel Ε. Neale, Puya Gharahkhani, Penelope M. Webb, Stuart MacGregor

    出版 2021
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  16. 16
    Single-cell multi-cohort dissection of the schizophrenia transcriptome

    Single-cell multi-cohort dissection of the schizophrenia transcriptome 由 W. Brad Ruzicka, Shahin Mohammadi, John F. Fullard, José Dávila-Velderrain, Sivan Subburaju, Daniel Reed Tso, Makayla Hourihan, Shan Jiang, Hao-Chih Lee, Jaroslav Bendl, Georgios Voloudakis, Vahram Haroutunian, Gabriel E. Hoffman, Panos Roussos, Manolis Kellis, Schahram Akbarian, Alexej Abyzov, Nadav Ahituv, Dhivya Arasappan, José Juan Almagro Armenteros, Brian J. Beliveau, Sabina Berretta, Rahul Bharadwaj, Arjun Bhattacharya, Lucy Bicks, Kristen Brennand, Davide Capauto, Frances A. Champagne, Tanima Chatterjee, Chris Chatzinakos, Yuhang Chen, H. Isaac Chen, Yuyan Cheng, Lijun Cheng, Andrew Chess, Jo-fan Chien, Zhiyuan Chu, Declan Clarke, Ashley Clement, Leonardo Collado‐Torres, Gregory M. Cooper, Gregory E. Crawford, Rujia Dai, Nikolaos P. Daskalakis, Amy Deep‐Soboslay, Chengyu Deng, Christopher P. DiPietro, Stella Dracheva, Shiron Drusinsky, Ziheng Duan, Duc M. Duong, Cagatay Dursun, Nicholas J. Eagles, Jonathan I. Edelstein, Prashant S. Emani, Kiki Galani, Timur R. Galeev, Michael J. Gandal, Sophia C. Gaynor, Mark Gerstein, Daniel H. Geschwind, Kiran Girdhar, Fernando S. Goes, William Greenleaf, Jennifer Grundman, Hanmin Guo, Qiuyu Guo, Chirag Gupta, Yoav Hadas, Joachim Hallmayer, Xikun Han, Natalie Hawken, Chuan He, Ella Henry, Stephanie C. Hicks, Marcus Ho, Li‐Lun Ho, Yi‐Ling Huang, Louise A. Huuki-Myers, Ahyeon Hwang, Thomas M. Hyde, Artemis Iatrou, Fumitaka Inoue, Aarti Jajoo, Matthew L. Jensen, Lihua Jiang, Peng Jin, Ting Jin, Connor Jops, Alexandre Jourdon, Riki Kawaguchi, Joel E. Kleinman, Steven P. Kleopoulos, Alexey Kozlenkov, Arnold R. Kriegstein, Anshul Kundaje, Soumya Kundu, Che-Yu Lee, Donghoon Lee, Junhao Li

    出版 2024
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  17. 17
    Cross-ancestry atlas of gene, isoform, and splicing regulation in the developing human brain

    Cross-ancestry atlas of gene, isoform, and splicing regulation in the developing human brain 由 Cindy Wen, Michael Margolis, Rujia Dai, Pan Zhang, Pawel F. Przytycki, Daniel Vo, Arjun Bhattacharya, Nana Matoba, Miao Tang, Chuan Jiao, Minsoo Kim, Ellen Tsai, Celine Hoh, Nil Aygün, Rebecca L. Walker, Christos Chatzinakos, Declan Clarke, Henry Pratt, Mette A. Peters, Mark Gerstein, Nikolaos P. Daskalakis, Zhiping Weng, Andrew E. Jaffe, Joel E. Kleinman, Thomas M. Hyde, Daniel R. Weinberger, Nicholas J. Bray, Nenad Šestan, Daniel H. Geschwind, Kathryn Roeder, Alexander Gusev, Bogdan Paşaniuc, Jason L. Stein, Michael I. Love, Katherine S. Pollard, Chunyu Liu, Michael J. Gandal, Schahram Akbarian, Alexej Abyzov, Nadav Ahituv, Dhivya Arasappan, José Juan Almagro Armenteros, Brian J. Beliveau, Jaroslav Bendl, Sabina Berretta, Rahul Bharadwaj, Lucy Bicks, Kristen Brennand, Davide Capauto, Frances A. Champagne, Tanima Chatterjee, Chris Chatzinakos, Yuhang Chen, H. Isaac Chen, Yuyan Cheng, Lijun Cheng, Andrew Chess, Jo-fan Chien, Zhiyuan Chu, Ashley Clement, Leonardo Collado‐Torres, Gregory M. Cooper, Gregory E. Crawford, José Dávila-Velderrain, Amy Deep‐Soboslay, Chengyu Deng, Christopher P. DiPietro, Stella Dracheva, Shiron Drusinsky, Ziheng Duan, Duc M. Duong, Cagatay Dursun, Nicholas J. Eagles, Jonathan I. Edelstein, Prashant S. Emani, John F. Fullard, Kiki Galani, Timur R. Galeev, Sophia C. Gaynor, Kiran Girdhar, Fernando S. Goes, William J. Greenleaf, Jennifer Grundman, Hanmin Guo, Qiuyu Guo, Chirag Gupta, Yoav Hadas, Joachim Hallmayer, Xikun Han, Vahram Haroutunian, Natalie Hawken, Chuan He, Ella Henry, Stephanie C. Hicks, Marcus Ho, Li‐Lun Ho, Gabriel E. Hoffman, Yi‐Ling Huang, Louise A. Huuki-Myers, Ahyeon Hwang

    出版 2024
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  18. 18
    Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries

    Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries 由 Puya Gharahkhani, Eric Jorgenson, Pirro G. Hysi, Anthony P. Khawaja, Sarah A. Pendergrass, Xikun Han, Jue‐Sheng Ong, Alex W. Hewitt, Ayellet V. Segrè, John M. Rouhana, Andrew R. Hamel, Robert P. Igo, Hélène Choquet, Ayub Qassim, Navya Shilpa Josyula, Jessica N. Cooke Bailey, Pieter W. M. Bonnemaijer, Adriana I. Iglesias, Owen M. Siggs, Terri L. Young, Véronique Vitart, Alberta A. H. J. Thiadens, Juha Karjalainen, Steffen Uebe, Ronald B. Melles, K. Saidas Nair, Robert Luben, Mark Simcoe, Nishani Amersinghe, Angela J. Cree, René Höhn, Alicia Poplawski, Li Jia Chen, Shi Song Rong, Tin Aung, Eranga N. Vithana, R. Rand Allingham, Murray H. Brilliant, Donald L. Budenz, Jessica N. Cooke Bailey, John H. Fingert, Douglas Gaasterland, Teresa Gaasterland, Jonathan L. Haines, Michael A. Hauser, Richard K. Lee, Paul R. Lichter, Yutao Liu, Sayoko E. Moroi, Jonathan S. Myers, Margaret A. Pericak‐Vance, Anthony Realini, Doug Rhee, Julia E. Richards, Robert Ritch, Joel S. Schuman, William K. Scott, Kuldev Singh, Arthur J. Sit, Douglas Vollrath, Robert N. Weinreb, Gadi Wollstein, Donald J. Zack, Shiwani Sharma, Sarah Martin, Tiger Zhou, Emmanuelle Souzeau, John E. Landers, Jude Fitzgerald, Richard Mills, Jamie E. Craig, Kathryn P. Burdon, Stuart L. Graham, Robert J. Casson, Ivan Goldberg, Andrew White, Paul R. Healey, David A. Mackey, Alex W. Hewitt, Masaki Shiono, Kazuo Misumi, Reiji Kaieda, Hiromasa Harada, Shiro Minami, Mitsuru Emi, Naoya Emoto, Hiroyuki Daida, Katsumi Miyauchi, Akira Murakami, Satoshi Asai, Mitsuhiko Moriyama, Yasuo Takahashi, Tomoaki Fujioka, Wataru Obara, Seijiro Mori, Hideki Ito, Satoshi Nagayama, Yoshio Miki, Akihide Masumoto, Akira Yamada

    出版 2021
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