Søgeresultater - Xian‐Man Zhang

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  1. 1
    Controlled-release mitochondrial protonophore reverses diabetes and steatohepatitis in rats

    Controlled-release mitochondrial protonophore reverses diabetes and steatohepatitis in rats af Rachel J. Perry, Dongyan Zhang, Xian‐Man Zhang, James L. Boyer, Gerald I. Shulman

    Udgivet 2015
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  2. 2
    Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 Diabetes

    Fasting hyperglycemia is not associated with increased expression of PEPCK or G6Pc in patients with Type 2 Diabetes af Varman T. Samuel, Sara A. Beddow, Takanori Iwasaki, Xian‐Man Zhang, Xin Chu, Christopher D. Still, Glenn S. Gerhard, Gerald I. Shulman

    Udgivet 2009
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  3. 3
    Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis

    Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis af Rachel J. Perry, Xian‐Man Zhang, Dongyan Zhang, Naoki Kumashiro, João Paulo Camporez, Gary W. Cline, Douglas L. Rothman, Gerald I. Shulman

    Udgivet 2014
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  4. 4
    Characterization of the Hyperphagic Response to Dietary Fat in the MC4R Knockout Mouse

    Characterization of the Hyperphagic Response to Dietary Fat in the MC4R Knockout Mouse af Dollada Srisai, Matthew P. Gillum, Brandon L. Panaro, Xian-Man Zhang, Naiphinich Kotchabhakdi, Gerald I. Shulman, Kate L. J. Ellacott, Roger D. Cone

    Udgivet 2011
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  5. 5
    Uncoupling Hepatic Oxidative Phosphorylation Reduces Tumor Growth in Two Murine Models of Colon Cancer

    Uncoupling Hepatic Oxidative Phosphorylation Reduces Tumor Growth in Two Murine Models of Colon Cancer af Yongliang Wang, Ali Nasiri, William Damsky, Curtis J. Perry, Xian‐Man Zhang, Aviva Rabin-Court, Michaël Pollak, Gerald I. Shulman, Rachel J. Perry

    Udgivet 2018
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  6. 6
    Apolipoprotein C3 Gene Variants in Nonalcoholic Fatty Liver Disease

    Apolipoprotein C3 Gene Variants in Nonalcoholic Fatty Liver Disease af Kitt Falk Petersen, Sylvie Dufour, Ali Hariri, Carol Nelson‐Williams, Jia Nee Foo, Xian‐Man Zhang, James Dziura, Richard P. Lifton, Gerald I. Shulman

    Udgivet 2010
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  7. 7
    A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain

    A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain af François R. Jornayvaz, Michael J. Jurczak, Hui‐Young Lee, Andreas L. Birkenfeld, David W. Frederick, Dongyang Zhang, Xian‐Man Zhang, Varman T. Samuel, Gerald I. Shulman

    Udgivet 2010
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  8. 8
    Non-invasive assessment of hepatic mitochondrial metabolism by positional isotopomer NMR tracer analysis (PINTA)

    Non-invasive assessment of hepatic mitochondrial metabolism by positional isotopomer NMR tracer analysis (PINTA) af Rachel J. Perry, Liang Peng, Gary W. Cline, Gina M. Butrico, Yongliang Wang, Xian‐Man Zhang, Douglas L. Rothman, Kitt Falk Petersen, Gerald I. Shulman

    Udgivet 2017
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  9. 9
    Leptin Mediates a Glucose-Fatty Acid Cycle to Maintain Glucose Homeostasis in Starvation

    Leptin Mediates a Glucose-Fatty Acid Cycle to Maintain Glucose Homeostasis in Starvation af Rachel J. Perry, Yongliang Wang, Gary W. Cline, Aviva Rabin-Court, Joongyu D. Song, Sylvie Dufour, Xian Man Zhang, Kitt Falk Petersen, Gerald I. Shulman

    Udgivet 2018
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  10. 10
    Propionate Increases Hepatic Pyruvate Cycling and Anaplerosis and Alters Mitochondrial Metabolism

    Propionate Increases Hepatic Pyruvate Cycling and Anaplerosis and Alters Mitochondrial Metabolism af Rachel J. Perry, Candace Borders, Gary W. Cline, Xian‐Man Zhang, Tiago C. Alves, Kitt Falk Petersen, Douglas L. Rothman, Richard G. Kibbey, Gerald I. Shulman

    Udgivet 2016
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  11. 11
    Effect of a ketogenic diet on hepatic steatosis and hepatic mitochondrial metabolism in nonalcoholic fatty liver disease

    Effect of a ketogenic diet on hepatic steatosis and hepatic mitochondrial metabolism in nonalcoholic fatty liver disease af Panu K. Luukkonen, Sylvie Dufour, Kun Lyu, Xian-Man Zhang, Antti Hakkarainen, Tiina E. Lehtimäki, Gary W. Cline, Kitt Falk Petersen, Gerald I. Shulman, Hannele Yki‐Järvinen

    Udgivet 2020
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  12. 12
    Sex‐ and strain‐specific effects of mitochondrial uncoupling on age‐related metabolic diseases in high‐fat diet‐fed mice

    Sex‐ and strain‐specific effects of mitochondrial uncoupling on age‐related metabolic diseases in high‐fat diet‐fed mice af Leigh Goedeke, Kelsey N. Murt, Andrea Di Francesco, João Paulo Camporez, Ali Nasiri, Yongliang Wang, Xian‐Man Zhang, Gary W. Cline, Rafael de Cabo, Gerald I. Shulman

    Udgivet 2022
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  13. 13
    Mechanisms by which a Very-Low-Calorie Diet Reverses Hyperglycemia in a Rat Model of Type 2 Diabetes

    Mechanisms by which a Very-Low-Calorie Diet Reverses Hyperglycemia in a Rat Model of Type 2 Diabetes af Rachel J. Perry, Liang Peng, Gary W. Cline, Yongliang Wang, Aviva Rabin-Court, Joongyu D. Song, Dongyan Zhang, Xian‐Man Zhang, Yuichi Nozaki, Sylvie Dufour, Kitt Falk Petersen, Gerald I. Shulman

    Udgivet 2017
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  14. 14
    Controlled-release mitochondrial protonophore (CRMP) reverses dyslipidemia and hepatic steatosis in dysmetabolic nonhuman primates

    Controlled-release mitochondrial protonophore (CRMP) reverses dyslipidemia and hepatic steatosis in dysmetabolic nonhuman primates af Leigh Goedeke, Liang Peng, Valle Montalvo-Romeral, Gina M. Butrico, Sylvie Dufour, Xian-Man Zhang, Rachel J. Perry, Gary W. Cline, Paul Kievit, Keefe Chng, Kitt Falk Petersen, Gerald I. Shulman

    Udgivet 2019
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  15. 15
    Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice

    Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice af Susanne Neschen, Katsutaro Morino, Linda E. Hammond, Dongyan Zhang, Zhen-Xiang Liu, Anthony J. Romanelli, Gary W. Cline, Rebecca L. Pongratz, Xian-Man Zhang, Cheol Soo Choi, Rosalind Coleman, Gerald I. Shulman

    Udgivet 2005
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  16. 16
    Reversal of Hypertriglyceridemia, Fatty Liver Disease, and Insulin Resistance by a Liver-Targeted Mitochondrial Uncoupler

    Reversal of Hypertriglyceridemia, Fatty Liver Disease, and Insulin Resistance by a Liver-Targeted Mitochondrial Uncoupler af Rachel J. Perry, Tae-Han Kim, Xian‐Man Zhang, Hui‐Young Lee, Dominik Pesta, Violeta Popov, Dongyan Zhang, Yasmeen Rahimi, Michael J. Jurczak, Gary W. Cline, David A. Spiegel, Gerald I. Shulman

    Udgivet 2013
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  17. 17
    The PNPLA3 I148M variant increases ketogenesis and decreases hepatic de novo lipogenesis and mitochondrial function in humans

    The PNPLA3 I148M variant increases ketogenesis and decreases hepatic de novo lipogenesis and mitochondrial function in humans af Panu K. Luukkonen, Kimmo Porthan, Noora Ahlholm, Fredrik Rosqvist, Sylvie Dufour, Xian‐Man Zhang, Tiina E. Lehtimäki, Wenla Seppänen, Marju Orho‐Melander, Leanne Hodson, Kitt Falk Petersen, Gerald I. Shulman, Hannele Yki‐Järvinen

    Udgivet 2023
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  18. 18
    Dissociation of Muscle Insulin Resistance from Alterations in Mitochondrial Substrate Preference

    Dissociation of Muscle Insulin Resistance from Alterations in Mitochondrial Substrate Preference af Joongyu D. Song, Tiago C. Alves, Douglas E. Befroy, Rachel J. Perry, Graeme F. Mason, Xian‐Man Zhang, Alexander Munk, Ye Zhang, Dongyan Zhang, Gary W. Cline, Douglas L. Rothman, Kitt Falk Petersen, Gerald I. Shulman

    Udgivet 2020
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  19. 19
    Metformin, phenformin, and galegine inhibit complex IV activity and reduce glycerol-derived gluconeogenesis

    Metformin, phenformin, and galegine inhibit complex IV activity and reduce glycerol-derived gluconeogenesis af Traci E. LaMoia, Gina M. Butrico, Hasini A. Kalpage, Leigh Goedeke, BRANDON T. HUBBARD, Daniel F. Vatner, Rafael Calais Gaspar, Xian‐Man Zhang, Gary W. Cline, Keita Nakahara, Seungwan Woo, Atsuhiro Shimada, Maik Hüttemann, Gerald I. Shulman

    Udgivet 2022
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  20. 20
    Insulin receptor Thr1160 phosphorylation mediates lipid-induced hepatic insulin resistance

    Insulin receptor Thr1160 phosphorylation mediates lipid-induced hepatic insulin resistance af Max C. Petersen, Anila K. Madiraju, Brandon M. Gassaway, Michael Marcel, Ali Nasiri, Gina M. Butrico, Melissa Marcucci, Dongyan Zhang, Abudukadier Abulizi, Xian‐Man Zhang, William M. Philbrick, Stevan R. Hubbard, Michael J. Jurczak, Varman T. Samuel, Jesse Rinehart, Gerald I. Shulman

    Udgivet 2016
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