Resultados de búsqueda - Willingham, Stephen
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Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling por Duncan, Joseph A., Bergstralh, Daniel T., Wang, Yanhong, Willingham, Stephen B., Ye, Zhengmao, Zimmermann, Albert G., Ting, Jenny Pan-Yun
Publicado 2007Texto -
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Learning from Host-Defense Peptides: Cationic, Amphipathic Peptoids with Potent Anticancer Activity por Huang, Wei, Seo, Jiwon, Willingham, Stephen B., Czyzewski, Ann M., Gonzalgo, Mark L., Weissman, Irving L., Barron, Annelise E.
Publicado 2014Texto -
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Use of a KIT-specific monoclonal antibody to bypass imatinib resistance in gastrointestinal stromal tumors por Edris, Badreddin, Willingham, Stephen, Weiskopf, Kipp, Volkmer, Anne K, Volkmer, Jens-Peter, Mühlenberg, Thomas, Weissman, Irving L, van de Rijn, Matt
Publicado 2013Texto -
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Therapeutic blockade of CXCR2 rapidly clears inflammation in arthritis and atopic dermatitis models: demonstration with surrogate and humanized antibodies por Alam, Md Jahangir, Xie, Liang, Ang, Caroline, Fahimi, Farnaz, Willingham, Stephen B., Kueh, Andrew J., Herold, Marco J., Mackay, Charles R., Robert, Remy
Publicado 2020Texto -
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NLRP3 (NALP3, cryopyrin) facilitates in vivo caspase-1, necrosis, & HMGB1 release via inflammasome-dependent and –independent pathways() por Willingham, Stephen B., Allen, Irving C., Bergstralh, Daniel T., Brickey, Willie June, Huang, Max Tze-Han, Taxman, Debra J, Duncan, Joseph A., Ting, Jenny P.-Y.
Publicado 2009Texto -
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Pre-Clinical Development of a Humanized Anti-CD47 Antibody with Anti-Cancer Therapeutic Potential por Liu, Jie, Wang, Lijuan, Zhao, Feifei, Tseng, Serena, Narayanan, Cyndhavi, Shura, Lei, Willingham, Stephen, Howard, Maureen, Prohaska, Susan, Volkmer, Jens, Chao, Mark, Weissman, Irving L., Majeti, Ravindra
Publicado 2015Texto -
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Neisseria gonorrhoeae activates the proteinase Cathepsin B to mediate the signaling activities of the NLRP3 and ASC - containing inflammasome por Duncan, Joseph A., Gao, Xi, Huang, Max, O’Connor, Brian P., Thomas, Christopher E., Willingham, Stephen B., Bergstralh, Daniel T., Jarvis, Gary A., Sparling, P. Frederick, Ting, Jenny P-Y.
Publicado 2009Texto -
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Anti-CD47 antibody–mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response por Tseng, Diane, Volkmer, Jens-Peter, Willingham, Stephen B., Contreras-Trujillo, Humberto, Fathman, John W., Fernhoff, Nathaniel B., Seita, Jun, Inlay, Matthew A., Weiskopf, Kipp, Miyanishi, Masanori, Weissman, Irving L.
Publicado 2013Texto -
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Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47 por Chao, Mark P., Jaiswal, Siddhartha, Weissman-Tsukamoto, Rachel, Alizadeh, Ash A., Gentles, Andrew J., Volkmer, Jens, Weiskopf, Kipp, Willingham, Stephen B., Raveh, Tal, Park, Christopher Y., Majeti, Ravindra, Weissman, Irving L.
Publicado 2010Texto -
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Microbial Pathogen-Induced Necrotic Cell Death Mediated by the Inflammasome Components CIAS1/Cryopyrin/NLRP3 and ASC por Willingham, Stephen B., Bergstralh, Daniel T., O’Connor, William, Morrison, Amy C., Taxman, Debra J., Duncan, Joseph A., Barnoy, Shoshana, Venkatesan, Malabi M., Flavell, Richard A., Deshmukh, Mohanish, Hoffman, Hal M., Ting, Jenny P.-Y.
Publicado 2007Texto -
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Combining CD47 blockade with trastuzumab eliminates HER2-positive breast cancer cells and overcomes trastuzumab tolerance por Upton, Rosalynd, Banuelos, Allison, Feng, Dongdong, Biswas, Tanuka, Kao, Kevin, McKenna, Kelly, Willingham, Stephen, Ho, Po Yi, Rosental, Benyamin, Tal, Michal Caspi, Raveh, Tal, Volkmer, Jens-Peter, Pegram, Mark D., Weissman, Irving L.
Publicado 2021Texto -
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Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcoma por Edris, Badreddin, Weiskopf, Kipp, Volkmer, Anne K., Volkmer, Jens-Peter, Willingham, Stephen B., Contreras-Trujillo, Humberto, Liu, Jie, Majeti, Ravindra, West, Robert B., Fletcher, Jonathan A., Beck, Andrew H., Weissman, Irving L., van de Rijn, Matt
Publicado 2012Texto -
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Anti-KIT monoclonal antibody inhibits imatinib-resistant gastrointestinal stromal tumor growth por Edris, Badreddin, Willingham, Stephen B., Weiskopf, Kipp, Volkmer, Anne K., Volkmer, Jens-Peter, Mühlenberg, Thomas, Montgomery, Kelli D., Contreras-Trujillo, Humberto, Czechowicz, Agnieszka, Fletcher, Jonathan A., West, Robert B., Weissman, Irving L., van de Rijn, Matt
Publicado 2013Texto -
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NLRC5-dependent activation of the inflammasome por Davis, Beckley K., Roberts, Reid A., Huang, Max T., Willingham, Stephen B., Conti, Brian J., Brickey, W. June, Barker, Brianne R., Kwan, Mildred, Taxman, Debra J., Accavitti-Loper, Mary-Ann, Duncan, Joseph A., Ting, Jenny P-Y.
Publicado 2010Texto -
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Isolation and mutational analysis of circulating tumor cells from lung cancer patients with magnetic sifters and biochips por Earhart, Christopher M., Hughes, Casey E., Gaster, Richard S., Ooi, Chin Chun, Wilson, Robert J., Zhou, Lisa Y., Humke, Eric W., Xu, Lingyun, Wong, Dawson J., Willingham, Stephen B., Schwartz, Erich J., Weissman, Irving L., Jeffrey, Stefanie S., Neal, Joel W., Rohatgi, Rajat, Wakelee, Heather A., Wang, Shan X.
Publicado 2014Texto -
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A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer por Betancur, Paola A., Abraham, Brian J., Yiu, Ying Y., Willingham, Stephen B., Khameneh, Farnaz, Zarnegar, Mark, Kuo, Angera H., McKenna, Kelly, Kojima, Yoko, Leeper, Nicholas J., Ho, Po, Gip, Phung, Swigut, Tomek, Sherwood, Richard I., Clarke, Michael F., Somlo, George, Young, Richard A., Weissman, Irving L.
Publicado 2017Texto -
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Identification of tumorigenic cells and therapeutic targets in pancreatic neuroendocrine tumors por Krampitz, Geoffrey Wayne, George, Benson M., Willingham, Stephen B., Volkmer, Jens-Peter, Weiskopf, Kipp, Jahchan, Nadine, Newman, Aaron M., Sahoo, Debashis, Zemek, Allison J., Yanovsky, Rebecca L., Nguyen, Julia K., Schnorr, Peter J., Mazur, Pawel K., Sage, Julien, Longacre, Teri A., Visser, Brendan C., Poultsides, George A., Norton, Jeffrey A., Weissman, Irving L.
Publicado 2016Texto