Risultati della ricerca - William R. Sellers

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  1. 1
    A Blueprint for Advancing Genetics-Based Cancer Therapy

    A Blueprint for Advancing Genetics-Based Cancer Therapy di William R. Sellers

    Pubblicazione 2011
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  2. 2
    Apoptosis and cancer drug targeting

    Apoptosis and cancer drug targeting di William R. Sellers, David E. Fisher

    Pubblicazione 1999
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  3. 3
    Oncogene addiction: pathways of therapeutic response, resistance, and road maps toward a cure

    Oncogene addiction: pathways of therapeutic response, resistance, and road maps toward a cure di Raymond Pagliarini, Wenlin Shao, William R. Sellers

    Pubblicazione 2015
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  4. 4
    Ribociclib (LEE011): Mechanism of Action and Clinical Impact of This Selective Cyclin-Dependent Kinase 4/6 Inhibitor in Various Solid Tumors

    Ribociclib (LEE011): Mechanism of Action and Clinical Impact of This Selective Cyclin-Dependent Kinase 4/6 Inhibitor in Various Solid Tumors di Debu Tripathy, Aditya Bardia, William R. Sellers

    Pubblicazione 2017
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  5. 5
    A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites.

    A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites. di William R. Sellers, J W Rodgers, William G. Kaelin

    Pubblicazione 1995
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  6. 6
    Phosphorylation of the PTEN Tail Regulates Protein Stability and Function

    Phosphorylation of the PTEN Tail Regulates Protein Stability and Function di Francisca Vázquez, Shivapriya Ramaswamy, Noriaki Nakamura, William R. Sellers

    Pubblicazione 2000
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  7. 7
    Targeting pan-essential genes in cancer: Challenges and opportunities

    Targeting pan-essential genes in cancer: Challenges and opportunities di Liang Chang, Paloma Ruiz, Takahiro Ito, William R. Sellers

    Pubblicazione 2021
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  8. 8
    A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR

    A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR di Shivapriya Ramaswamy, Noriaki Nakamura, Isabelle Sansal, Louise Bergeron, William R. Sellers

    Pubblicazione 2002
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  9. 9
    Transcription of the E2F-1 gene is rendered cell cycle dependent by E2F DNA-binding sites within its promoter.

    Transcription of the E2F-1 gene is rendered cell cycle dependent by E2F DNA-binding sites within its promoter. di Elizabeth Neuman, E K Flemington, William R. Sellers, William G. Kaelin

    Pubblicazione 1994
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  10. 10
    BCR/ABL Regulates Expression of the Cyclin-dependent Kinase Inhibitor p27Kip1 through the Phosphatidylinositol 3-Kinase/AKT Pathway

    BCR/ABL Regulates Expression of the Cyclin-dependent Kinase Inhibitor p27Kip1 through the Phosphatidylinositol 3-Kinase/AKT Pathway di Franck Gesbert, William R. Sellers, Sabina Signoretti, Massimo Loda, James D. Griffin

    Pubblicazione 2000
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  11. 11
    TSC2 regulates VEGF through mTOR-dependent and -independent pathways

    TSC2 regulates VEGF through mTOR-dependent and -independent pathways di James Brugarolas, Francisca Vázquez, Archana Reddy, William R. Sellers, William G. Kaelin

    Pubblicazione 2003
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  12. 12
    Forkhead Transcription Factors Are Critical Effectors of Cell Death and Cell Cycle Arrest Downstream of PTEN

    Forkhead Transcription Factors Are Critical Effectors of Cell Death and Cell Cycle Arrest Downstream of PTEN di Noriaki Nakamura, Shivapriya Ramaswamy, Francisca Vázquez, Sabina Signoretti, Massimo Loda, William R. Sellers

    Pubblicazione 2000
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  13. 13
    Signal Transducer and Activator of Transcription 3 Is Required for the Oncogenic Effects of Non–Small-Cell Lung Cancer–Associated Mutations of the Epidermal Growth Factor Receptor

    Signal Transducer and Activator of Transcription 3 Is Required for the Oncogenic Effects of Non–Small-Cell Lung Cancer–Associated Mutations of the Epidermal Growth Factor Receptor... di James V. Alvarez, Heidi Greulich, William R. Sellers, Matthew Meyerson, David A. Frank

    Pubblicazione 2006
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  14. 14
    GEMINI: a variational Bayesian approach to identify genetic interactions from combinatorial CRISPR screens

    GEMINI: a variational Bayesian approach to identify genetic interactions from combinatorial CRISPR screens di Mahdi Zamanighomi, Sidharth Jain, Takahiro Ito, Debjani Pal, Timothy Daley, William R. Sellers

    Pubblicazione 2019
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  15. 15
    Tumor suppressor PTEN acts through dynamic interaction with the plasma membrane

    Tumor suppressor PTEN acts through dynamic interaction with the plasma membrane di Francisca Vázquez, Satomi Matsuoka, William R. Sellers, Toshio Yanagida, Masahiro Ueda, Peter N. Devreotes

    Pubblicazione 2006
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  16. 16
    Phosphorylation of the PTEN Tail Acts as an Inhibitory Switch by Preventing Its Recruitment into a Protein Complex

    Phosphorylation of the PTEN Tail Acts as an Inhibitory Switch by Preventing Its Recruitment into a Protein Complex di Francisca Vázquez, Steven R. Grossman, Yuki Takahashi, Mihail Rokas, Noriaki Nakamura, William R. Sellers

    Pubblicazione 2001
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  17. 17
    Mechanistic Insights into Maintenance of High p53 Acetylation by PTEN

    Mechanistic Insights into Maintenance of High p53 Acetylation by PTEN di Andrew G. Li, Landon G. Piluso, Xin Cai, Gang Wei, William R. Sellers, Xuan Liu

    Pubblicazione 2006
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  18. 18
    Regulation of G<sub>1</sub>progression by the<i>PTEN</i>tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway

    Regulation of G<sub>1</sub>progression by the<i>PTEN</i>tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway di Shivapriya Ramaswamy, Noriaki Nakamura, Francisca Vázquez, David Batt, S Perera, Thomas M. Roberts, William R. Sellers

    Pubblicazione 1999
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  19. 19
    Epidermal Growth Factor–Independent Transformation of Ba/F3 Cells with Cancer-Derived Epidermal Growth Factor Receptor Mutants Induces Gefitinib-Sensitive Cell Cycle Progression

    Epidermal Growth Factor–Independent Transformation of Ba/F3 Cells with Cancer-Derived Epidermal Growth Factor Receptor Mutants Induces Gefitinib-Sensitive Cell Cycle Progression di Jingrui Jiang, Heidi Greulich, Pasi A. Jänne, William R. Sellers, Matthew Meyerson, James D. Griffin

    Pubblicazione 2005
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  20. 20
    PTEN Nuclear Localization Is Regulated by Oxidative Stress and Mediates p53-Dependent Tumor Suppression

    PTEN Nuclear Localization Is Regulated by Oxidative Stress and Mediates p53-Dependent Tumor Suppression di Chun-Ju Chang, David J. Mulholland, Bahram Valamehr, Sherly Mosessian, William R. Sellers, Hong Wu

    Pubblicazione 2008
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