Search Results - Wen‐Ning Zhao

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  1. 1
    A High-Throughput Screen for Wnt/β-Catenin Signaling Pathway Modulators in Human iPSC-Derived Neural Progenitors

    A High-Throughput Screen for Wnt/β-Catenin Signaling Pathway Modulators in Human iPSC-Derived Neural Progenitors by Wen‐Ning Zhao, Chialin Cheng, Kraig M. Theriault, Steven D. Sheridan, Li‐Huei Tsai, Stephen J. Haggarty

    Published 2012
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  2. 2
    Selectivity and Kinetic Requirements of HDAC Inhibitors as Progranulin Enhancers for Treating Frontotemporal Dementia

    Selectivity and Kinetic Requirements of HDAC Inhibitors as Progranulin Enhancers for Treating Frontotemporal Dementia by Angela She, Iren Kurtser, Surya A. Reis, Krista M. Hennig, Jenny Lai, Audrey Lang, Wen-Ning Zhao, Ralph Mazitschek, Bradford C. Dickerson, Joachim Herz, Stephen J. Haggarty

    Published 2017
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  3. 3
    A high-throughput kinome screen reveals serum/glucocorticoid-regulated kinase 1 as a therapeutic target for NF2-deficient meningiomas

    A high-throughput kinome screen reveals serum/glucocorticoid-regulated kinase 1 as a therapeutic target for NF2-deficient meningiomas by Roberta L. Beauchamp, Marianne F. James, Patrick DeSouza, Vilas Wagh, Wen‐Ning Zhao, Justin T. Jordan, Anat Stemmer‐Rachamimov, Scott R. Plotkin, James F. Gusella, Stephen J. Haggarty, Vijaya Ramesh

    Published 2015
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  4. 4
    HDAC6 Brain Mapping with [<sup>18</sup>F]Bavarostat Enabled by a Ru-Mediated Deoxyfluorination

    HDAC6 Brain Mapping with [<sup>18</sup>F]Bavarostat Enabled by a Ru-Mediated Deoxyfluorination by Martin G. Strebl, Arthur J. Campbell, Wen‐Ning Zhao, Frederick A. Schroeder, Misha M. Riley, Peter S. Chindavong, Thomas Morin, Stephen J. Haggarty, Florence F. Wagner, Tobias Ritter, Jacob M. Hooker

    Published 2017
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  5. 5
    High-throughput brain activity mapping and machine learning as a foundation for systems neuropharmacology

    High-throughput brain activity mapping and machine learning as a foundation for systems neuropharmacology by Xudong Lin, Xin Duan, Claire S. Jacobs, Jeremy F.P. Ullmann, Chung-Yuen Chan, Siya Chen, Shuk Han Cheng, Wen-Ning Zhao, Annapurna Poduri, Xin Wang, Stephen J. Haggarty, Peng Shi

    Published 2018
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  6. 6
    Unbiased Cell-based Screening in a Neuronal Cell Model of Batten Disease Highlights an Interaction between Ca2+ Homeostasis, Autophagy, and CLN3 Protein Function

    Unbiased Cell-based Screening in a Neuronal Cell Model of Batten Disease Highlights an Interaction between Ca2+ Homeostasis, Autophagy, and CLN3 Protein Function by Uma Chandrachud, Mathew Walker, Alexandra M. Simas, Sasja Heetveld, Anton Petcherski, Madeleine Klein, Hyejin Oh, Pavlina Wolf, Wen‐Ning Zhao, Stephanie Norton, Stephen J. Haggarty, Emyr Lloyd–Evans, Susan L. Cotman

    Published 2015
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  7. 7
    Short-Chain HDAC Inhibitors Differentially Affect Vertebrate Development and Neuronal Chromatin

    Short-Chain HDAC Inhibitors Differentially Affect Vertebrate Development and Neuronal Chromatin by Daniel M. Fass, Rishita Shah, Balaram Ghosh, Krista M. Hennig, Stephanie Norton, Wen‐Ning Zhao, Surya A. Reis, Peter S. Klein, Ralph Mazitschek, Rebecca L. Maglathlin, Timothy A. Lewis, Stephen J. Haggarty

    Published 2010
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  8. 8
    A screen for regulators of survival of motor neuron protein levels

    A screen for regulators of survival of motor neuron protein levels by Nina R. Makhortova, Monica Hayhurst, Antonio Cerqueira, Amy D Sinor-Anderson, Wen‐Ning Zhao, Patrick W. Heiser, Anthony C. Arvanites, Lance S. Davidow, Zachary Waldon, Judith A. Steen, Kelvin Lam, Hien D. Ngo, Lee L. Rubin

    Published 2011
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  9. 9
    Brain-Specific Phosphorylation of MeCP2 Regulates Activity-Dependent Bdnf Transcription, Dendritic Growth, and Spine Maturation

    Brain-Specific Phosphorylation of MeCP2 Regulates Activity-Dependent Bdnf Transcription, Dendritic Growth, and Spine Maturation by Zhaolan Zhou, Elizabeth J. Hong, Sonia Cohen, Wen-Ning Zhao, Hsin‐Yi Henry Ho, Lauren Schmidt, Wen Chen, Yingxi Lin, Erin M. Savner, Eric C. Griffith, Linda Hu, Judith A. Steen, Charles J. Weitz, Michael E. Greenberg

    Published 2006
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  10. 10
    Crebinostat: A novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity

    Crebinostat: A novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity by Daniel M. Fass, Surya A. Reis, Balaram Ghosh, Krista M. Hennig, Nadine F. Joseph, Wen‐Ning Zhao, Thomas J.F. Nieland, Ji‐Song Guan, Chelsea E. Groves Kuhnle, Weiping Tang, Douglas Barker, Ralph Mazitschek, Stuart L. Schreiber, Li‐Huei Tsai, Stephen J. Haggarty

    Published 2012
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  11. 11
    A Selective HDAC 1/2 Inhibitor Modulates Chromatin and Gene Expression in Brain and Alters Mouse Behavior in Two Mood-Related Tests

    A Selective HDAC 1/2 Inhibitor Modulates Chromatin and Gene Expression in Brain and Alters Mouse Behavior in Two Mood-Related Tests by Frederick A. Schroeder, Michael C. Lewis, Daniel M. Fass, Florence F. Wagner, Yanling Zhang, Krista M. Hennig, Jennifer Gale, Wen‐Ning Zhao, Surya A. Reis, Douglas Barker, Erin Berry-Scott, Sung Won Kim, Elizabeth L. Clore, Jacob M. Hooker, Edward B. Holson, Stephen J. Haggarty, Tracey L. Petryshen

    Published 2013
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  12. 12
    Kinetically selective inhibitors of histone deacetylase 2 (HDAC2) as cognition enhancers

    Kinetically selective inhibitors of histone deacetylase 2 (HDAC2) as cognition enhancers by Florence F. Wagner, Yarong Zhang, Daniel M. Fass, Naima T. Joseph, Jennifer Gale, Michel Weïwer, Patrick McCarren, Stewart L. Fisher, Taner Kaya, Wen‐Ning Zhao, Surya A. Reis, Krista M. Hennig, Melvin E. Thomas, Bérénice C. Lemercier, Michael C. Lewis, Ji‐Song Guan, M. P. Moyer, Edward M. Scolnick, Stephen J. Haggarty, Li‐Huei Tsai, Edward B. Holson

    Published 2014
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  13. 13
    Structural Basis for Achieving GSK-3β Inhibition with High Potency, Selectivity, and Brain Exposure for Positron Emission Tomography Imaging and Drug Discovery

    Structural Basis for Achieving GSK-3β Inhibition with High Potency, Selectivity, and Brain Exposure for Positron Emission Tomography Imaging and Drug Discovery by Vadim Bernard‐Gauthier, Andrew V. Mossine, Ashley C. Knight, Debasis Patnaik, Wen‐Ning Zhao, Chialin Cheng, Hema S. Krishnan, Lucius L. Xuan, Peter S. Chindavong, Surya A. Reis, Jinshan Michael Chen, Xia Shao, Jenelle Stauff, Janna Arteaga, Phillip Sherman, Nicolas Salem, David R. Bonsall, Brenda Amaral, Cassis Varlow, Lisa Wells, Laurent Martarello, Shil Patel, Steven H. Liang, Ravi G. Kurumbail, Stephen J. Haggarty, Peter J. H. Scott, Neil Vasdev

    Published 2019
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  14. 14
    Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis

    Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis by Brian T. D. Tobe, Andrew Crain, Alicia M. Winquist, Barbara Calabrese, Hiroko Makihara, Wen‐Ning Zhao, Jasmin Lalonde, Haruko Nakamura, Glenn Konopaske, Michelle M. Sidor, Cameron D. Pernia, Naoya Yamashita, Moyuka Wada‐Irimada, Yuuka Inoue, Fumio Nakamura, Steven D. Sheridan, Ryan W. Logan, Michael G. Brandel, Dongmei Wu, Joshua Hunsberger, Laurel Dorsett, Cordulla Duerr, Ranor C.B. Basa, Michael J. McCarthy, Namrata D. Udeshi, Philipp Mertins, Steven A. Carr, Guy A. Rouleau, Lina Mastrangelo, Jianxue Li, Gustavo J. Gutierrez, Laurence M. Brill, Nikolaos Venizelos, Guang Chen, Jeffrey S. Nye, Husseini K. Manji, Jeffrey H. Price, Colleen A. McClung, Hagop S. Akiskal, Martin Alda, D M Chuang, Joseph T. Coyle, Yang Liu, Yang D. Teng, Toshio Ohshima, Katsuhiko Mikoshiba, Richard L. Sidman, Shelley Halpain, Stephen J. Haggarty, Yoshio Goshima, Evan Y. Snyder

    Published 2017
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  15. 15
    A Next Generation Connectivity Map: L1000 Platform And The First 1,000,000 Profiles

    A Next Generation Connectivity Map: L1000 Platform And The First 1,000,000 Profiles by Aravind Subramanian, Rajiv Narayan, Steven M. Corsello, D. D. Peck, Ted Natoli, Xiaodong Lü, Joshua Gould, John F. Davis, Andrew A. Tubelli, Jacob K. Asiedu, David L. Lahr, Jodi Hirschman, Zihan Liu, Melanie Donahue, Bina Julian, Mariya Khan, David Wadden, Ian C. P. Smith, Daniel D. Lam, Arthur Liberzon, Courtney Toder, Mukta Bagul, Marek Orzechowski, Oana M. Enache, Federica Piccioni, Alice H. Berger, Alykhan F. Shamji, Angela N. Brooks, Anita Vrcic, Corey Flynn, Jacqueline Rosains, David Y. Takeda, Desiree Davison, Justin Lamb, Kristin Ardlie, Larson Hogstrom, Nathanael S. Gray, Paul A. Clemons, Serena J. Silver, Xiaoyun Wu, Wen‐Ning Zhao, Willis Read-Button, Xiaohua Wu, Stephen J. Haggarty, Lucienne Ronco, Jesse S. Boehm, Stuart L. Schreiber, John G. Doench, Joshua A. Bittker, David E. Root, Bang Wong, Todd R. Golub

    Published 2017
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  16. 16
    A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles

    A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles by Aravind Subramanian, Rajiv Narayan, Steven M. Corsello, D. D. Peck, Ted Natoli, Xiaodong Lü, Joshua Gould, John F. Davis, Andrew A. Tubelli, Jacob K. Asiedu, David L. Lahr, Jodi Hirschman, Zihan Liu, Melanie Donahue, Bina Julian, Mariya Khan, David Wadden, Ian C. P. Smith, Daniel D. Lam, Arthur Liberzon, Courtney Toder, Mukta Bagul, Marek Orzechowski, Oana M. Enache, Federica Piccioni, Sarah Johnson, Nicholas Lyons, Alice H. Berger, Alykhan F. Shamji, Angela N. Brooks, Anita Vrcic, Corey Flynn, Jacqueline Rosains, David Y. Takeda, Roger Hu, Desiree Davison, Justin Lamb, Kristin Ardlie, Larson Hogstrom, Peyton Greenside, Nathanael S. Gray, Paul A. Clemons, Serena J. Silver, Xiaoyun Wu, Wen‐Ning Zhao, Willis Read-Button, Xiaohua Wu, Stephen J. Haggarty, Lucienne Ronco, Jesse S. Boehm, Stuart L. Schreiber, John G. Doench, Joshua A. Bittker, David E. Root, Bang Wong, Todd R. Golub

    Published 2017
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