Search Results - Wedge, David C

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  1. 1
    A unified haplotype-based method for accurate and comprehensive variant calling

    A unified haplotype-based method for accurate and comprehensive variant calling by Cooke, Daniel P., Wedge, David C., Lunter, Gerton

    Published 2021
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  2. 2
    Benchmarking small-variant genotyping in polyploids

    Benchmarking small-variant genotyping in polyploids by Cooke, Daniel P., Wedge, David C., Lunter, Gerton

    Published 2022
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  3. 3
    Principles of Reconstructing the Subclonal Architecture of Cancers

    Principles of Reconstructing the Subclonal Architecture of Cancers by Dentro, Stefan C., Wedge, David C., Van Loo, Peter

    Published 2017
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  4. 4
    Re-evaluating experimental validation in the Big Data Era: a conceptual argument

    Re-evaluating experimental validation in the Big Data Era: a conceptual argument by Jafari, Mohieddin, Guan, Yuanfang, Wedge, David C., Ansari-Pour, Naser

    Published 2021
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  5. 5
    APOBEC3 mutational signatures are associated with extensive and diverse genomic instability across multiple tumour types

    APOBEC3 mutational signatures are associated with extensive and diverse genomic instability across multiple tumour types by Jakobsdottir, G. Maria, Brewer, Daniel S, Cooper, Colin, Green, Catherine, Wedge, David C

    Published 2022
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  6. 6
    Analysis of a complete DNA–protein affinity landscape

    Analysis of a complete DNA–protein affinity landscape by Rowe, William, Platt, Mark, Wedge, David C., Day, Philip J., Kell, Douglas B., Knowles, Joshua

    Published 2010
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  7. 7
    Deciphering Signatures of Mutational Processes Operative in Human Cancer

    Deciphering Signatures of Mutational Processes Operative in Human Cancer by Alexandrov, Ludmil B., Nik-Zainal, Serena, Wedge, David C., Campbell, Peter J., Stratton, Michael R.

    Published 2013
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  8. 8
    FDRAnalysis: A tool for the integrated analysis of tandem mass spectrometry identification results from multiple search engines

    FDRAnalysis: A tool for the integrated analysis of tandem mass spectrometry identification results from multiple search engines by Wedge, David C, Krishna, Ritesh, Blackhurst, Paul, Siepen, Jennifer A, Jones, Andrew R., Hubbard, Simon J.

    Published 2011
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  9. 9
    CONSeQuence: Prediction of Reference Peptides for Absolute Quantitative Proteomics Using Consensus Machine Learning Approaches

    CONSeQuence: Prediction of Reference Peptides for Absolute Quantitative Proteomics Using Consensus Machine Learning Approaches by Eyers, Claire E., Lawless, Craig, Wedge, David C., Lau, King Wai, Gaskell, Simon J., Hubbard, Simon J.

    Published 2011
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  10. 10
    Reference bias in the Illumina Isaac aligner

    Reference bias in the Illumina Isaac aligner by Cornish, Alex J, Chubb, Daniel, Frangou, Anna, Hoang, Phuc H, Kaiser, Martin, Wedge, David C, Houlston, Richard S

    Published 2020
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  11. 11
    Clock-like mutational processes in human somatic cells

    Clock-like mutational processes in human somatic cells by Alexandrov, Ludmil B., Jones, Philip H., Wedge, David C., Sale, Julian E., Campbell, Peter J., Nik-Zainal, Serena, Stratton, Michael R.

    Published 2015
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  12. 12
    Array-based evolution of DNA aptamers allows modelling of an explicit sequence-fitness landscape

    Array-based evolution of DNA aptamers allows modelling of an explicit sequence-fitness landscape by Knight, Christopher G., Platt, Mark, Rowe, William, Wedge, David C., Khan, Farid, Day, Philip J. R., McShea, Andy, Knowles, Joshua, Kell, Douglas B.

    Published 2009
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  13. 13
    Automated workflows for accurate mass-based putative metabolite identification in LC/MS-derived metabolomic datasets

    Automated workflows for accurate mass-based putative metabolite identification in LC/MS-derived metabolomic datasets by Brown, Marie, Wedge, David C., Goodacre, Royston, Kell, Douglas B., Baker, Philip N., Kenny, Louise C., Mamas, Mamas A., Neyses, Ludwig, Dunn, Warwick B.

    Published 2011
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  14. 14
    Automated workflows for accurate mass-based putative metabolite identification in LC/MS-derived metabolomic datasets

    Automated workflows for accurate mass-based putative metabolite identification in LC/MS-derived metabolomic datasets by Brown, Marie, Wedge, David C., Goodacre, Royston, Kell, Douglas B., Baker, Philip N., Kenny, Louise C., Mamas, Mamas A., Neyses, Ludwig, Dunn, Warwick B.

    Published 2012
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  15. 15
    A practical guide to cancer subclonal reconstruction from DNA sequencing

    A practical guide to cancer subclonal reconstruction from DNA sequencing by Tarabichi, Maxime, Salcedo, Adriana, Deshwar, Amit G., Leathlobhair, Máire Ni, Wintersinger, Jeff, Wedge, David C., Loo, Peter Van, Morris, Quaid D., Boutros, Paul C.

    Published 2021
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  16. 16
    Perturbed hematopoietic stem and progenitor cell hierarchy in myelodysplastic syndromes patients with monosomy 7 as the sole cytogenetic abnormality

    Perturbed hematopoietic stem and progenitor cell hierarchy in myelodysplastic syndromes patients with monosomy 7 as the sole cytogenetic abnormality by Dimitriou, Marios, Woll, Petter S., Mortera-Blanco, Teresa, Karimi, Mohsen, Wedge, David C., Doolittle, Helen, Douagi, Iyadh, Papaemmanuil, Elli, Jacobsen, Sten Eirik W., Hellström-Lindberg, Eva

    Published 2016
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  17. 17
    Neutral tumor evolution?

    Neutral tumor evolution? by Tarabichi, Maxime, Martincorena, Iñigo, Gerstung, Moritz, Leroi, Armand M., Markowetz, Florian, Spellman, Paul T., Morris, Quaid D., Lingjærde, Ole Christian, Wedge, David C., Van Loo, Peter

    Published 2018
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  18. 18
    Malignant transformation and genetic alterations are uncoupled in early colorectal cancer progression

    Malignant transformation and genetic alterations are uncoupled in early colorectal cancer progression by Mamlouk, Soulafa, Simon, Tincy, Tomás, Laura, Wedge, David C., Arnold, Alexander, Menne, Andrea, Horst, David, Capper, David, Morkel, Markus, Posada, David, Sers, Christine, Bläker, Hendrik

    Published 2020
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  19. 19
    Fast randomization of large genomic datasets while preserving alteration counts

    Fast randomization of large genomic datasets while preserving alteration counts by Gobbi, Andrea, Iorio, Francesco, Dawson, Kevin J., Wedge, David C., Tamborero, David, Alexandrov, Ludmil B., Lopez-Bigas, Nuria, Garnett, Mathew J., Jurman, Giuseppe, Saez-Rodriguez, Julio

    Published 2014
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  20. 20
    ascatNgs: Identifying Somatically Acquired Copy-Number Alterations from Whole-Genome Sequencing Data

    ascatNgs: Identifying Somatically Acquired Copy-Number Alterations from Whole-Genome Sequencing Data by Raine, Keiran M., Van Loo, Peter, Wedge, David C., Jones, David, Menzies, Andrew, Butler, Adam P., Teague, Jon W., Tarpey, Patrick, Nik-Zainal, Serena, Campbell, Peter J.

    Published 2016
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