Resultats de la cerca - Wedge, David C

A unified haplotype-based method for accurate and comprehensive variant calling per Cooke, Daniel P., Wedge, David C., Lunter, Gerton

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Benchmarking small-variant genotyping in polyploids per Cooke, Daniel P., Wedge, David C., Lunter, Gerton

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Principles of Reconstructing the Subclonal Architecture of Cancers per Dentro, Stefan C., Wedge, David C., Van Loo, Peter

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Re-evaluating experimental validation in the Big Data Era: a conceptual argument per Jafari, Mohieddin, Guan, Yuanfang, Wedge, David C., Ansari-Pour, Naser

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APOBEC3 mutational signatures are associated with extensive and diverse genomic instability across multiple tumour types per Jakobsdottir, G. Maria, Brewer, Daniel S, Cooper, Colin, Green, Catherine, Wedge, David C

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Analysis of a complete DNA–protein affinity landscape per Rowe, William, Platt, Mark, Wedge, David C., Day, Philip J., Kell, Douglas B., Knowles, Joshua

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Deciphering Signatures of Mutational Processes Operative in Human Cancer per Alexandrov, Ludmil B., Nik-Zainal, Serena, Wedge, David C., Campbell, Peter J., Stratton, Michael R.

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FDRAnalysis: A tool for the integrated analysis of tandem mass spectrometry identification results from multiple search engines per Wedge, David C, Krishna, Ritesh, Blackhurst, Paul, Siepen, Jennifer A, Jones, Andrew R., Hubbard, Simon J.

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CONSeQuence: Prediction of Reference Peptides for Absolute Quantitative Proteomics Using Consensus Machine Learning Approaches per Eyers, Claire E., Lawless, Craig, Wedge, David C., Lau, King Wai, Gaskell, Simon J., Hubbard, Simon J.

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Reference bias in the Illumina Isaac aligner per Cornish, Alex J, Chubb, Daniel, Frangou, Anna, Hoang, Phuc H, Kaiser, Martin, Wedge, David C, Houlston, Richard S

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Clock-like mutational processes in human somatic cells per Alexandrov, Ludmil B., Jones, Philip H., Wedge, David C., Sale, Julian E., Campbell, Peter J., Nik-Zainal, Serena, Stratton, Michael R.

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Array-based evolution of DNA aptamers allows modelling of an explicit sequence-fitness landscape per Knight, Christopher G., Platt, Mark, Rowe, William, Wedge, David C., Khan, Farid, Day, Philip J. R., McShea, Andy, Knowles, Joshua, Kell, Douglas B.

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Automated workflows for accurate mass-based putative metabolite identification in LC/MS-derived metabolomic datasets per Brown, Marie, Wedge, David C., Goodacre, Royston, Kell, Douglas B., Baker, Philip N., Kenny, Louise C., Mamas, Mamas A., Neyses, Ludwig, Dunn, Warwick B.

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Automated workflows for accurate mass-based putative metabolite identification in LC/MS-derived metabolomic datasets per Brown, Marie, Wedge, David C., Goodacre, Royston, Kell, Douglas B., Baker, Philip N., Kenny, Louise C., Mamas, Mamas A., Neyses, Ludwig, Dunn, Warwick B.

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A practical guide to cancer subclonal reconstruction from DNA sequencing per Tarabichi, Maxime, Salcedo, Adriana, Deshwar, Amit G., Leathlobhair, Máire Ni, Wintersinger, Jeff, Wedge, David C., Loo, Peter Van, Morris, Quaid D., Boutros, Paul C.

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Perturbed hematopoietic stem and progenitor cell hierarchy in myelodysplastic syndromes patients with monosomy 7 as the sole cytogenetic abnormality per Dimitriou, Marios, Woll, Petter S., Mortera-Blanco, Teresa, Karimi, Mohsen, Wedge, David C., Doolittle, Helen, Douagi, Iyadh, Papaemmanuil, Elli, Jacobsen, Sten Eirik W., Hellström-Lindberg, Eva

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Neutral tumor evolution? per Tarabichi, Maxime, Martincorena, Iñigo, Gerstung, Moritz, Leroi, Armand M., Markowetz, Florian, Spellman, Paul T., Morris, Quaid D., Lingjærde, Ole Christian, Wedge, David C., Van Loo, Peter

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Malignant transformation and genetic alterations are uncoupled in early colorectal cancer progression per Mamlouk, Soulafa, Simon, Tincy, Tomás, Laura, Wedge, David C., Arnold, Alexander, Menne, Andrea, Horst, David, Capper, David, Morkel, Markus, Posada, David, Sers, Christine, Bläker, Hendrik

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Fast randomization of large genomic datasets while preserving alteration counts per Gobbi, Andrea, Iorio, Francesco, Dawson, Kevin J., Wedge, David C., Tamborero, David, Alexandrov, Ludmil B., Lopez-Bigas, Nuria, Garnett, Mathew J., Jurman, Giuseppe, Saez-Rodriguez, Julio

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ascatNgs: Identifying Somatically Acquired Copy-Number Alterations from Whole-Genome Sequencing Data per Raine, Keiran M., Van Loo, Peter, Wedge, David C., Jones, David, Menzies, Andrew, Butler, Adam P., Teague, Jon W., Tarpey, Patrick, Nik-Zainal, Serena, Campbell, Peter J.

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