Výsledky vyhledávání - Wang, Zhulun

IRAK-4 Inhibitors for Inflammation Autor Wang, Zhulun, Wesche, Holger, Stevens, Tracey, Walker, Nigel, Yeh, Wen-Chen

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The structure of mitogen-activated protein kinase p38 at 2.1-Å resolution Autor Wang, Zhulun, Harkins, Paul C., Ulevitch, Richard J., Han, Jiahuai, Cobb, Melanie H., Goldsmith, Elizabeth J.

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Agonistic β-Klotho antibody mimics fibroblast growth factor 21 (FGF21) functions Autor Min, Xiaoshan, Weiszmann, Jennifer, Johnstone, Sheree, Wang, Wei, Yu, Xinchao, Romanow, William, Thibault, Stephen, Li, Yang, Wang, Zhulun

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Cryo-EM structure of ABCG5/G8 in complex with modulating antibodies Autor Zhang, Hanzhi, Huang, Ching-Shin, Yu, Xinchao, Lee, Jonas, Vaish, Amit, Chen, Qing, Zhou, Mingyue, Wang, Zhulun, Min, Xiaoshan

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Protocol for high-throughput cloning, expression, purification, and evaluation of bispecific antibodies Autor Li, Danqing, Partin, Alexander C., Zhao, Liangjun, Chen, Irwin, Michaels, Mark L., Wang, Zhulun, Garces, Fernando, Gong, Danyang, Riley, Timothy P.

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FGF19-induced Hepatocyte Proliferation Is Mediated through FGFR4 Activation Autor Wu, Xinle, Ge, Hongfei, Lemon, Bryan, Vonderfecht, Steven, Weiszmann, Jennifer, Hecht, Randy, Gupte, Jamila, Hager, Todd, Wang, Zhulun, Lindberg, Richard, Li, Yang

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Separating mitogenic and metabolic activities of fibroblast growth factor 19 (FGF19) Autor Wu, Xinle, Ge, Hongfei, Lemon, Bryan, Vonderfecht, Steven, Baribault, Helene, Weiszmann, Jennifer, Gupte, Jamila, Gardner, Jonitha, Lindberg, Richard, Wang, Zhulun, Li, Yang

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A systematic dissection of sequence elements determining β-Klotho and FGF interaction and signaling Autor Shi, Sally Yu, Lu, Ya-Wen, Richardson, Jason, Min, Xiaoshan, Weiszmann, Jennifer, Richards, William G., Wang, Zhulun, Zhang, Zhongqi, Zhang, Jun, Li, Yang

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Cryo-EM structures of NPC1L1 reveal mechanisms of cholesterol transport and ezetimibe inhibition Autor Huang, Ching-Shin, Yu, Xinchao, Fordstrom, Preston, Choi, Kaylee, Chung, Ben C., Roh, Soung-Hun, Chiu, Wah, Zhou, Mingyue, Min, Xiaoshan, Wang, Zhulun

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The serum protein transthyretin as a platform for dimerization and tetramerization of antibodies and Fab fragments to enable target clustering Autor Walker, Kenneth W., Foltz, Ian N., Wang, Tina, Salimi-Moosavi, Hossein, Bailis, Julie M., Lee, Fei, An, Phillip, Smith, Stephen, Bruno, Richele, Wang, Zhulun

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Rational selection of building blocks for the assembly of bispecific antibodies Autor Gong, Danyang, Riley, Timothy P., Bzymek, Krzysztof P., Correia, Ana R., Li, Danqing, Spahr, Christopher, Robinson, John H., Case, Ryan B., Wang, Zhulun, Garces, Fernando

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Structure of the Nuclear Factor κB-inducing Kinase (NIK) Kinase Domain Reveals a Constitutively Active Conformation Autor Liu, Jinsong, Sudom, Athena, Min, Xiaoshan, Cao, Zhaodan, Gao, Xiong, Ayres, Merrill, Lee, Fei, Cao, Ping, Johnstone, Sheree, Plotnikova, Olga, Walker, Nigel, Chen, Guoqing, Wang, Zhulun

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Next generation Fc scaffold for multispecific antibodies Autor Estes, Bram, Sudom, Athena, Gong, Danyang, Whittington, Douglas A., Li, Vivian, Mohr, Christopher, Li, Danqing, Riley, Timothy P., Shi, Stone D.-H., Zhang, Jun, Garces, Fernando, Wang, Zhulun

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Enhancing the Prefusion Conformational Stability of SARS-CoV-2 Spike Protein Through Structure-Guided Design Autor Riley, Timothy P., Chou, Hui-Ting, Hu, Ruozhen, Bzymek, Krzysztof P., Correia, Ana R., Partin, Alexander C., Li, Danqing, Gong, Danyang, Wang, Zhulun, Yu, Xinchao, Manzanillo, Paolo, Garces, Fernando

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Structure-guided Discovery of Dual-recognition Chemibodies Autor Cheng, Alan C., Doherty, Elizabeth M., Johnstone, Sheree, DiMauro, Erin F., Dao, Jennifer, Luthra, Abhinav, Ye, Jay, Tang, Jie, Nixey, Thomas, Min, Xiaoshan, Tagari, Philip, Miranda, Les P., Wang, Zhulun

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Discovery and molecular basis of potent noncovalent inhibitors of fatty acid amide hydrolase (FAAH) Autor Min, Xiaoshan, Thibault, Stephen T., Porter, Amy C., Gustin, Darin J., Carlson, Timothy J., Xu, Haoda, Lindstrom, Michelle, Xu, Guifen, Uyeda, Craig, Ma, Zhihua, Li, Yihong, Kayser, Frank, Walker, Nigel P. C., Wang, Zhulun

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The high-resolution crystal structure of human LCAT(1) Autor Piper, Derek E., Romanow, William G., Gunawardane, Ruwanthi N., Fordstrom, Preston, Masterman, Stephanie, Pan, Oscar, Thibault, Stephen T., Zhang, Richard, Meininger, David, Schwarz, Margrit, Wang, Zhulun, King, Chadwick, Zhou, Mingyue, Walker, Nigel P. C.

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Identification and Characterization of a Non-retinoid Ligand for Retinol-binding Protein 4 Which Lowers Serum Retinol-binding Protein 4 Levels in Vivo Autor Motani, Alykhan, Wang, Zhulun, Conn, Marion, Siegler, Karen, Zhang, Ying, Liu, Qingxiang, Johnstone, Sheree, Xu, Haoda, Thibault, Steve, Wang, Yingcai, Fan, Pingchen, Connors, Richard, Le, Hoa, Xu, Guifen, Walker, Nigel, Shan, Bei, Coward, Peter

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Molecular basis for the loss-of-function effects of the Alzheimer's disease–associated R47H variant of the immune receptor TREM2 Autor Sudom, Athena, Talreja, Santosh, Danao, Jean, Bragg, Eric, Kegel, Rob, Min, Xiaoshan, Richardson, Jason, Zhang, Zhongqi, Sharkov, Nikolai, Marcora, Edoardo, Thibault, Steve, Bradley, Jodi, Wood, Steve, Lim, Ai-Ching, Chen, Hang, Wang, Songli, Foltz, Ian N., Sambashivan, Shilpa, Wang, Zhulun

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Molecular mechanism of an antagonistic antibody against glucose-dependent insulinotropic polypeptide receptor Autor Min, Xiaoshan, Yie, Junming, Wang, Jinghong, Chung, Ben C., Huang, Ching-Shin, Xu, Haoda, Yang, Jie, Deng, Liying, Lin, Joanne, Chen, Qing, Abbott, Christina M., Gundel, Caroline, Thibault, Stephen A., Meng, Tina, Bates, Darren L., Lloyd, David J., Véniant, Murielle M., Wang, Zhulun

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