Sökresultat - Wagle, Nikhil

mTOR Inhibitors in Cancer: What Can We Learn from Exceptional Responses?() av Kwiatkowski, David J., Wagle, Nikhil

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Precision Medicine in Breast Cancer: Genes, Genomes, and the Future of Genomically-Driven Treatments av Stover, Daniel G., Wagle, Nikhil

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Clinical Analysis and Interpretation of Cancer Genome Data av Van Allen, Eliezer M., Wagle, Nikhil, Levy, Mia A.

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cDNA-detector: detection and removal of cDNA contamination in DNA sequencing libraries av Qi, Meifang, Nayar, Utthara, Ludwig, Leif S., Wagle, Nikhil, Rheinbay, Esther

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MicroRNA-Mediated Suppression of the TGF-β Pathway Confers Transmissible and Reversible CDK4/6 Inhibitor Resistance av Cornell, Liam, Wander, Seth A., Visal, Tanvi, Wagle, Nikhil, Shapiro, Geoffrey I.

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ERK Mutations Confer Resistance to Mitogen-Activated Protein Kinase Pathway Inhibitors av Goetz, Eva M., Ghandi, Mahmoud, Treacy, Daniel J., Wagle, Nikhil, Garraway, Levi A.

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ER+ Breast Cancer Strongly Depends on MCL-1 and BCL-xL Anti-Apoptotic Proteins av Alcon, Clara, Zañudo, Jorge Gómez Tejeda, Albert, Reka, Wagle, Nikhil, Scaltriti, Maurizio, Letai, Anthony, Samitier, Josep, Montero, Joan

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MULTIPLEXED ELIMINATION OF WILD-TYPE DNA AND HIGH RESOLUTION MELTING PRIOR TO TARGETED RESEQUENCING OF LIQUID BIOPSIES av Ladas, Ioannis, Fitarelli-Kiehl, Mariana, Song, Chen, Adalsteinsson, Viktor A., Parsons, Heather A., Lin, Nancy U., Wagle, Nikhil, Makrigiorgos, G. Mike

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A genome-scale RNA interference screen implicates NF1 loss in resistance to RAF inhibition av Whittaker, Steven R., Theurillat, Jean-Philippe, Van Allen, Eliezer, Wagle, Nikhil, Hsiao, Jessica, Cowley, Glenn S., Schadendorf, Dirk, Root, David E., Garraway, Levi A.

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Phase I Trial of a Tablet Formulation of Pilaralisib, a Pan‐Class I PI3K Inhibitor, in Patients with Advanced Solid Tumors av Edelman, Gerald, Rodon, Jordi, Lager, Joanne, Castell, Christelle, Jiang, Jason, Van Allen, Eliezer M., Wagle, Nikhil, Lindeman, Neal I., Sholl, Lynette M., Shapiro, Geoffrey I.

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Discordant cellular response to pre-surgical letrozole in bilateral synchronous ER+ breast cancers with a KRAS mutation or FGFR1 gene amplification av Balko, Justin M., Mayer, Ingrid A., Sanders, Melinda E., Miller, Todd W., Kuba, Maria G., Meszoely, Ingrid M., Wagle, Nikhil, Garraway, Levi A., Arteaga, Carlos L.

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Low Frequency Clonal Mutations Recoverable by Deep Sequencing in Patients with Aplastic Anemia av Lane, Andrew A., Odejide, Oreofe, Kopp, Nadja, Kim, Sunhee, Yoda, Akinori, Erlich, Rachel, Wagle, Nikhil, Abel, Gregory A., Rodig, Scott J., Antin, Joseph H., Weinstock, David M.

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Cell line-specific network models of ER+ breast cancer identify potential PI3Kα inhibitor resistance mechanisms and drug combinations av Zañudo, Jorge Gómez Tejeda, Mao, Pingping, Alcon, Clara, Kowalski, Kailey, Johnson, Gabriela N., Xu, Guotai, Baselga, Jose, Scaltriti, Maurizio, Letai, Anthony, Montero, Joan, Albert, Réka, Wagle, Nikhil

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Clinicopathological Features Among Patients With Advanced Human Epidermal Growth Factor–2-Positive Breast Cancer With Prolonged Clinical Benefit to First-Line Trastuzumab-Based The... av Vaz-Luis, Ines, Seah, Davinia, Olson, Erin M., Wagle, Nikhil, Metzger-Filho, Otto, Sohl, Jessica, Litsas, Georgia, Burstein, Harold J., Krop, Ian E., Winer, Eric P., Lin, Nancy U.

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The fuzzy world of precision medicine: deliberations of a precision medicine tumor board av McGraw, Sarah A, Garber, Judy, Jänne, Pasi A, Lindeman, Neal, Oliver, Nelly, Sholl, Lynette M, Van Allen, Eliezer M, Wagle, Nikhil, Garraway, Levi A, Joffe, Steven, Gray, Stacy W

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Dissecting Therapeutic Resistance to RAF Inhibition in Melanoma by Tumor Genomic Profiling av Wagle, Nikhil, Emery, Caroline, Berger, Michael F., Davis, Matthew J., Sawyer, Allison, Pochanard, Panisa, Kehoe, Sarah M., Johannessen, Cory M., MacConaill, Laura E., Hahn, William C., Meyerson, Matthew, Garraway, Levi A.

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High-Throughput Detection of Actionable Genomic Alterations in Clinical Tumor Samples by Targeted, Massively Parallel Sequencing av Wagle, Nikhil, Berger, Michael F., Davis, Matthew J., Blumenstiel, Brendan, DeFelice, Matthew, Pochanard, Panisa, Ducar, Matthew, Van Hummelen, Paul, MacConaill, Laura E., Hahn, William C., Meyerson, Matthew, Gabriel, Stacey B., Garraway, Levi A.

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Everolimus and pazopanib (E/P) benefit genomically selected patients with metastatic urothelial carcinoma av Bellmunt, Joaquim, Lalani, Aly-Khan A., Jacobus, Sussana, Wankowicz, Stephanie A., Polacek, Laura, Takeda, David Y., Harshman, Lauren C., Wagle, Nikhil, Moreno, Irene, Lundgren, Kevin, Bossé, Dominick, Van Allen, Eliezer M., Choueiri, Toni K., Rosenberg, Jonathan E.

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Identification of a RAS-activating TMEM87A-RASGRF1 fusion in an exceptional responder to sunitinib with non-small cell lung cancer av Cooper, Alissa J, Kobayashi, Yoshihisa, Kim, Dewey, Clifford, Sarah E, Kravets, Sasha, Dahlberg, Suzanne E, Chambers, Emily S, Li, Jiaqi, Rangachari, Deepa, Nguyen, Tom, Costa, Daniel B, Rabin, Michael S, Wagle, Nikhil, Sholl, Lynette M, Jänne, Pasi A, Oxnard, Geoffrey R

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Oncologists' and Cancer Patients' Views on Whole-Exome Sequencing and Incidental Findings: Results from The CanSeq Study av Gray, Stacy W., Park, Elyse R., Najita, Julie, Martins, Yolanda, Traeger, Lara, Bair, Elizabeth, Gagne, Joshua, Garber, Judy, Jänne, Pasi A., Lindeman, Neal, Lowenstein, Carol, Oliver, Nelly, Sholl, Lynette, Van Allen, Eliezer M., Wagle, Nikhil, Wood, Sam, Garraway, Levi, Joffe, Steven

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