検索結果 - Wagle, Nikhil

mTOR Inhibitors in Cancer: What Can We Learn from Exceptional Responses?() 著者: Kwiatkowski, David J., Wagle, Nikhil

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Precision Medicine in Breast Cancer: Genes, Genomes, and the Future of Genomically-Driven Treatments 著者: Stover, Daniel G., Wagle, Nikhil

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Clinical Analysis and Interpretation of Cancer Genome Data 著者: Van Allen, Eliezer M., Wagle, Nikhil, Levy, Mia A.

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cDNA-detector: detection and removal of cDNA contamination in DNA sequencing libraries 著者: Qi, Meifang, Nayar, Utthara, Ludwig, Leif S., Wagle, Nikhil, Rheinbay, Esther

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MicroRNA-Mediated Suppression of the TGF-β Pathway Confers Transmissible and Reversible CDK4/6 Inhibitor Resistance 著者: Cornell, Liam, Wander, Seth A., Visal, Tanvi, Wagle, Nikhil, Shapiro, Geoffrey I.

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ERK Mutations Confer Resistance to Mitogen-Activated Protein Kinase Pathway Inhibitors 著者: Goetz, Eva M., Ghandi, Mahmoud, Treacy, Daniel J., Wagle, Nikhil, Garraway, Levi A.

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ER+ Breast Cancer Strongly Depends on MCL-1 and BCL-xL Anti-Apoptotic Proteins 著者: Alcon, Clara, Zañudo, Jorge Gómez Tejeda, Albert, Reka, Wagle, Nikhil, Scaltriti, Maurizio, Letai, Anthony, Samitier, Josep, Montero, Joan

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MULTIPLEXED ELIMINATION OF WILD-TYPE DNA AND HIGH RESOLUTION MELTING PRIOR TO TARGETED RESEQUENCING OF LIQUID BIOPSIES 著者: Ladas, Ioannis, Fitarelli-Kiehl, Mariana, Song, Chen, Adalsteinsson, Viktor A., Parsons, Heather A., Lin, Nancy U., Wagle, Nikhil, Makrigiorgos, G. Mike

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A genome-scale RNA interference screen implicates NF1 loss in resistance to RAF inhibition 著者: Whittaker, Steven R., Theurillat, Jean-Philippe, Van Allen, Eliezer, Wagle, Nikhil, Hsiao, Jessica, Cowley, Glenn S., Schadendorf, Dirk, Root, David E., Garraway, Levi A.

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Phase I Trial of a Tablet Formulation of Pilaralisib, a Pan‐Class I PI3K Inhibitor, in Patients with Advanced Solid Tumors 著者: Edelman, Gerald, Rodon, Jordi, Lager, Joanne, Castell, Christelle, Jiang, Jason, Van Allen, Eliezer M., Wagle, Nikhil, Lindeman, Neal I., Sholl, Lynette M., Shapiro, Geoffrey I.

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Discordant cellular response to pre-surgical letrozole in bilateral synchronous ER+ breast cancers with a KRAS mutation or FGFR1 gene amplification 著者: Balko, Justin M., Mayer, Ingrid A., Sanders, Melinda E., Miller, Todd W., Kuba, Maria G., Meszoely, Ingrid M., Wagle, Nikhil, Garraway, Levi A., Arteaga, Carlos L.

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Low Frequency Clonal Mutations Recoverable by Deep Sequencing in Patients with Aplastic Anemia 著者: Lane, Andrew A., Odejide, Oreofe, Kopp, Nadja, Kim, Sunhee, Yoda, Akinori, Erlich, Rachel, Wagle, Nikhil, Abel, Gregory A., Rodig, Scott J., Antin, Joseph H., Weinstock, David M.

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Cell line-specific network models of ER+ breast cancer identify potential PI3Kα inhibitor resistance mechanisms and drug combinations 著者: Zañudo, Jorge Gómez Tejeda, Mao, Pingping, Alcon, Clara, Kowalski, Kailey, Johnson, Gabriela N., Xu, Guotai, Baselga, Jose, Scaltriti, Maurizio, Letai, Anthony, Montero, Joan, Albert, Réka, Wagle, Nikhil

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Clinicopathological Features Among Patients With Advanced Human Epidermal Growth Factor–2-Positive Breast Cancer With Prolonged Clinical Benefit to First-Line Trastuzumab-Based The... 著者: Vaz-Luis, Ines, Seah, Davinia, Olson, Erin M., Wagle, Nikhil, Metzger-Filho, Otto, Sohl, Jessica, Litsas, Georgia, Burstein, Harold J., Krop, Ian E., Winer, Eric P., Lin, Nancy U.

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The fuzzy world of precision medicine: deliberations of a precision medicine tumor board 著者: McGraw, Sarah A, Garber, Judy, Jänne, Pasi A, Lindeman, Neal, Oliver, Nelly, Sholl, Lynette M, Van Allen, Eliezer M, Wagle, Nikhil, Garraway, Levi A, Joffe, Steven, Gray, Stacy W

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Dissecting Therapeutic Resistance to RAF Inhibition in Melanoma by Tumor Genomic Profiling 著者: Wagle, Nikhil, Emery, Caroline, Berger, Michael F., Davis, Matthew J., Sawyer, Allison, Pochanard, Panisa, Kehoe, Sarah M., Johannessen, Cory M., MacConaill, Laura E., Hahn, William C., Meyerson, Matthew, Garraway, Levi A.

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High-Throughput Detection of Actionable Genomic Alterations in Clinical Tumor Samples by Targeted, Massively Parallel Sequencing 著者: Wagle, Nikhil, Berger, Michael F., Davis, Matthew J., Blumenstiel, Brendan, DeFelice, Matthew, Pochanard, Panisa, Ducar, Matthew, Van Hummelen, Paul, MacConaill, Laura E., Hahn, William C., Meyerson, Matthew, Gabriel, Stacey B., Garraway, Levi A.

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Everolimus and pazopanib (E/P) benefit genomically selected patients with metastatic urothelial carcinoma 著者: Bellmunt, Joaquim, Lalani, Aly-Khan A., Jacobus, Sussana, Wankowicz, Stephanie A., Polacek, Laura, Takeda, David Y., Harshman, Lauren C., Wagle, Nikhil, Moreno, Irene, Lundgren, Kevin, Bossé, Dominick, Van Allen, Eliezer M., Choueiri, Toni K., Rosenberg, Jonathan E.

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Identification of a RAS-activating TMEM87A-RASGRF1 fusion in an exceptional responder to sunitinib with non-small cell lung cancer 著者: Cooper, Alissa J, Kobayashi, Yoshihisa, Kim, Dewey, Clifford, Sarah E, Kravets, Sasha, Dahlberg, Suzanne E, Chambers, Emily S, Li, Jiaqi, Rangachari, Deepa, Nguyen, Tom, Costa, Daniel B, Rabin, Michael S, Wagle, Nikhil, Sholl, Lynette M, Jänne, Pasi A, Oxnard, Geoffrey R

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Oncologists' and Cancer Patients' Views on Whole-Exome Sequencing and Incidental Findings: Results from The CanSeq Study 著者: Gray, Stacy W., Park, Elyse R., Najita, Julie, Martins, Yolanda, Traeger, Lara, Bair, Elizabeth, Gagne, Joshua, Garber, Judy, Jänne, Pasi A., Lindeman, Neal, Lowenstein, Carol, Oliver, Nelly, Sholl, Lynette, Van Allen, Eliezer M., Wagle, Nikhil, Wood, Sam, Garraway, Levi, Joffe, Steven

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