Risultati della ricerca - Vrajesh Karkhanis
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Versatility of PRMT5-induced methylation in growth control and development di Vrajesh Karkhanis, Yujie Hu, Robert A. Baiocchi, Anthony N. Imbalzano, Saı̈d Sif
Pubblicazione 2011Revisão -
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PRMT5–PTEN molecular pathway regulates senescence and self-renewal of primary glioblastoma neurosphere cells di Yeshavanth Banasavadi‐Siddegowda, Luke Russell, E. Frair, Vrajesh Karkhanis, Theresa Relation, Ji Young Yoo, J. Zhang, Saı̈d Sif, Jaime Imitola, Robert A. Baiocchi, Balveen Kaur
Pubblicazione 2016Artigo -
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Protein Arginine Methyltransferase 5 (PRMT5) Inhibition Induces Lymphoma Cell Death through Reactivation of the Retinoblastoma Tumor Suppressor Pathway and Polycomb Repressor Compl... di Ji-Hyun Chung, Vrajesh Karkhanis, Sookil Tae, Fengting Yan, Porsha Smith, Leona W. Ayers, Claudio Agostinelli, Stefano Pileri, Gerald V. Denis, Robert A. Baiocchi, Saı̈d Sif
Pubblicazione 2013Artigo -
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PRMT5-Selective Inhibitors Suppress Inflammatory T Cell Responses and Experimental Autoimmune Encephalomyelitis di Lindsay Webb, Stephanie A. Amici, Kyle Jablonski, Himanshu Savardekar, Amanda R. Panfil, Linsen Li, Wei Zhou, Kevin J. Peine, Vrajesh Karkhanis, Eric M. Bachelder, Kristy M. Ainslie, Patrick L. Green, Chenglong Li, Robert A. Baiocchi, Mireia Guerau‐de‐Arellano
Pubblicazione 2017Artigo -
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Mechanistic basis and efficacy of targeting the β-catenin–TCF7L2–JMJD6–c-Myc axis to overcome resistance to BET inhibitors di Dyana T. Saenz, Warren Fiskus, Christopher P. Mill, Dimuthu Perera, Taghi Manshouri, Bernardo H Lara, Vrajesh Karkhanis, Sunil Sharma, Stephen Horrigan, Prithviraj Bose, Tapan M. Kadia, Lucia Masárová, Courtney D. DiNardo, Gautam Borthakur, Joseph D. Khoury, Koichi Takahashi, Srividya Bhaskara, Charles Y. Lin, Michael R. Green, Cristian Coarfa, Craig M. Crews, Srđan Verstovšek, Kapil N. Bhalla
Pubblicazione 2020Artigo -
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Selective inhibition of protein arginine methyltransferase 5 blocks initiation and maintenance of B-cell transformation di Lapo Alinari, Kiran V. Mahasenan, Fengting Yan, Vrajesh Karkhanis, Ji-Hyun Chung, Emily M. Smith, Carl Quinion, Porsha L. Smith, Lisa Kim, John T. Patton, Rosa Lapalombella, Bo Yu, Yun Wu, Satavisha Roy, Alessandra De Leo, Stefano Pileri, Claudio Agostinelli, Leona W. Ayers, James E. Bradner, Selina Chen‐Kiang, Olivier Elemento, Tasneem Motiwala, Sarmila Majumder, John C. Byrd, Samson T. Jacob, Saı̈d Sif, Chenglong Li, Robert A. Baiocchi
Pubblicazione 2015Artigo
Strumenti per la ricerca:
Soggetti correlati
Biology
Gene
Genetics
Methylation
Methyltransferase
Protein arginine methyltransferase 5
Cancer research
Cell biology
Epigenetics
Gene expression
Amino acid
DNA methylation
Gene silencing
Histone
Histone methyltransferase
Immunology
Psychological repression
Arginine
Biochemistry
Cell
Cell cycle
Chromatin
Derepression
Histone H3
Lymphoma
Molecular biology
PRC2
Promoter
Protein kinase B
Regulation of gene expression