Rezultati - Volmar, Claude-Henry

Orphan Diseases: State of the Drug Discovery Art od Volmar, Claude-Henry, Wahlestedt, Claes, Brothers, Shaun

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CD40 deficiency mitigates Alzheimer's disease pathology in transgenic mouse models od Laporte, Vincent, Ait-Ghezala, Ghania, Volmar, Claude-Henry, Mullan, Michael

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Differential Effects of the Gβ5-RGS7 Complex on Muscarinic M3 Receptor–Induced Ca(2+) Influx and Release od Karpinsky-Semper, Darla, Volmar, Claude-Henry, Brothers, Shaun P., Slepak, Vladlen Z.

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Sexual Dimorphism in the 3xTg-AD Mouse Model and Its Impact on Pre-Clinical Research od Dennison, Jessica L., Ricciardi, Natalie R., Lohse, Ines, Volmar, Claude-Henry, Wahlestedt, Claes

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Safety and pharmacokinetics of a highly bioavailable resveratrol preparation (JOTROL (TM)) od Kemper, Christopher, Behnam, Dariush, Brothers, Shaun, Wahlestedt, Claes, Volmar, Claude-Henry, Bennett, Daniel, Hayward, Marshall

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The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer’s Disease od Magistri, Marco, Velmeshev, Dmitry, Makhmutova, Madina, Patel, Prutha, Sartor, Gregory C., Volmar, Claude-Henry, Wahlestedt, Claes, Faghihi, Mohammad Ali

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Ovarian Cancer Treatment Stratification Using Ex Vivo Drug Sensitivity Testing od LOHSE, INES, AZZAM, DIANA J., AL-ALI, HASSAN, VOLMAR, CLAUDE-HENRY, BROTHERS, SHAUN P., INCE, TAN A., WAHLESTEDT, CLAES

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Helix 8 and the i3 Loop of the Muscarinic M3 Receptor Are Crucial Sites for Its Regulation by the Gβ5-RGS7 Complex od Karpinsky-Semper, Darla, Tayou, Junior, Levay, Konstantin, Schuchardt, Brett J., Bhat, Vikas, Volmar, Claude-Henry, Farooq, Amjad, Slepak, Vladlen Z.

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Ex vivo drug sensitivity testing as a means for drug repurposing in esophageal adenocarcinoma od Lohse, Ines, Al-Ali, Hassan, Volmar, Claude-Henry, D. Alvarez Trotta, Annamil, Brothers, Shaun P., Capobianco, Anthony J., Wahlestedt, Claes

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Inhibition of HDAC3 reverses Alzheimer’s disease-related pathologies in vitro and in the 3xTg-AD mouse model od Janczura, Karolina J., Volmar, Claude-Henry, Sartor, Gregory C., Rao, Sunil J., Ricciardi, Natalie R., Lambert, Guerline, Brothers, Shaun P., Wahlestedt, Claes

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Vitamin C sensitizes melanoma to BET inhibitors od Mustafi, Sushmita, Camarena, Vladimir, Volmar, Claude-Henry, Huff, Tyler C., Sant, David W., Brothers, Shaun P., Liu, Zhao-Jun, Wahlestedt, Claes, Wang, Gaofeng

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HDAC Inhibitors Induce BDNF Expression and Promote Neurite Outgrowth in Human Neural Progenitor Cells-Derived Neurons od Bagheri, Amir, Habibzadeh, Parham, Razavipour, Seyedeh Fatemeh, Volmar, Claude-Henry, Chee, Nancy T., Brothers, Shaun P., Wahlestedt, Claes, Mowla, Seyed Javad, Faghihi, Mohammad Ali

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A novel knockout mouse model of the noncoding antisense Brain-Derived Neurotrophic Factor (Bdnf) gene displays increased endogenous Bdnf protein and improved memory function follow... od Modarresi, Farzaneh, Pedram Fatemi, Roya, Razavipour, Seyedeh Fatemeh, Ricciardi, Natalie, Makhmutova, Madina, Khoury, Nathalie, Magistri, Marco, Volmar, Claude-Henry, Wahlestedt, Claes, Faghihi, Mohammad Ali

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Selective Antihypertensive Dihydropyridines Lower Aβ Accumulation by Targeting both the Production and the Clearance of Aβ across the Blood-Brain Barrier od Paris, Daniel, Bachmeier, Corbin, Patel, Nikunj, Quadros, Amita, Volmar, Claude-Henry, Laporte, Vincent, Ganey, Jim, Beaulieu-Abdelahad, David, Ait-Ghezala, Ghania, Crawford, Fiona, Mullan, Michael J

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The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation od Pastori, Chiara, Kapranov, Philipp, Penas, Clara, Peschansky, Veronica, Volmar, Claude-Henry, Sarkaria, Jann N., Bregy, Amade, Komotar, Ricardo, St. Laurent, Georges, Ayad, Nagi G., Wahlestedt, Claes

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The BET Bromodomain Inhibitor I-BET151 Acts Downstream of Smoothened Protein to Abrogate the Growth of Hedgehog Protein-driven Cancers od Long, Jun, Li, Bin, Rodriguez-Blanco, Jezabel, Pastori, Chiara, Volmar, Claude-Henry, Wahlestedt, Claes, Capobianco, Anthony, Bai, Feng, Pei, Xin-Hai, Ayad, Nagi G., Robbins, David J.

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A human-based multi-gene signature enables quantitative drug repurposing for metabolic disease od Timmons, James A, Anighoro, Andrew, Brogan, Robert J, Stahl, Jack, Wahlestedt, Claes, Farquhar, David Gordon, Taylor-King, Jake, Volmar, Claude-Henry, Kraus, William E, Phillips, Stuart M

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Vitamin C supplementation expands the therapeutic window of BETi for triple negative breast cancer od Mustafi, Sushmita, Camarena, Vladimir, Qureshi, Rehana, Yoon, Hyunho, Volmar, Claude-Henry, Huff, Tyler C., Sant, David W., Zheng, Lihong, Brothers, Shaun P., Wahlestedt, Claes, Slingerland, Joyce, Wang, Gaofeng

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Longevity‐related molecular pathways are subject to midlife “switch” in humans od Timmons, James A., Volmar, Claude‐Henry, Crossland, Hannah, Phillips, Bethan E., Sood, Sanjana, Janczura, Karolina J., Törmäkangas, Timo, Kujala, Urho M., Kraus, William E., Atherton, Philip J., Wahlestedt, Claes

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An Ultra-High Throughput Screen for catalytic Inhibitors of Serine /Threonine Protein Phosphatases Types 1 and 5 (PP1C and PP5C) od Swingle, Mark, Volmar, Claude-Henry, Saldanha, S. Adrian, Chase, Peter, Eberhart, Christina, Salter, Edward A., D’Arcy, Brandon, Schroeder, Chad E., Golden, Jennifer E., Wierzbicki, Andrzej, Hodder, Peter, Honkanen, Richard E.

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