Hakutulokset - Vinothini Rajeeve

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  1. 1
    Reconstructing kinase network topologies from phosphoproteomics data reveals cancer-associated rewiring

    Reconstructing kinase network topologies from phosphoproteomics data reveals cancer-associated rewiring Tekijä Maruan Hijazi, Ryan Smith, Vinothini Rajeeve, Conrad Bessant, Pedro R. Cutillas

    Julkaistu 2020
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  2. 2
    Phosphoproteomics identifies determinants of PAK inhibitor sensitivity in leukaemia cells

    Phosphoproteomics identifies determinants of PAK inhibitor sensitivity in leukaemia cells Tekijä Pedro Casado, Santiago Marfà, Marwa Mohammed Hadi, Henry Gerdes, Sandra M. Martín‐Guerrero, Farideh Miraki‐Moud, Vinothini Rajeeve, Pedro R. Cutillas

    Julkaistu 2025
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  3. 3
    Shedding of bevacizumab in tumour cells-derived extracellular vesicles as a new therapeutic escape mechanism in glioblastoma

    Shedding of bevacizumab in tumour cells-derived extracellular vesicles as a new therapeutic escape mechanism in glioblastoma Tekijä Thomas R. Simon, Sotiria Pinioti, Pascale Schellenberger, Vinothini Rajeeve, Franz Wendler, Pedro R. Cutillas, Alice A. K. King, Justin Stebbing, Georgios Giamas

    Julkaistu 2018
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  4. 4
    Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics

    Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics Tekijä Alexandra Naba, Oliver M.T. Pearce, Amanda Del Rosario, Duanduan Ma, Huiming Ding, Vinothini Rajeeve, Pedro R. Cutillas, Frances R. Balkwill, Richard O. Hynes

    Julkaistu 2017
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  5. 5
    Oxidative Stress in Cells with Extra Centrosomes Drives Non-Cell-Autonomous Invasion

    Oxidative Stress in Cells with Extra Centrosomes Drives Non-Cell-Autonomous Invasion Tekijä Teresa Arnandis, Pedro Monteiro, Sophie D. Adams, Victoria L. Bridgeman, Vinothini Rajeeve, Emanuela Gadaleta, Jacek Marzec, Claude Chelala, Ilaria Malanchi, Pedro R. Cutillas, Susana A. Godinho

    Julkaistu 2018
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  6. 6
    Versican Associates with Tumor Immune Phenotype and Limits T-cell Trafficking via Chondroitin Sulfate

    Versican Associates with Tumor Immune Phenotype and Limits T-cell Trafficking via Chondroitin Sulfate Tekijä Priyanka Hirani, Jacqueline McDermott, Vinothini Rajeeve, Pedro R. Cutillas, J. Louise Jones, Daniel J. Pennington, Thomas N. Wight, Salvatore Santamaria, Kimberly M. Alonge, Oliver M.T. Pearce

    Julkaistu 2024
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  7. 7
    Proteomic and genomic integration identifies kinase and differentiation determinants of kinase inhibitor sensitivity in leukemia cells

    Proteomic and genomic integration identifies kinase and differentiation determinants of kinase inhibitor sensitivity in leukemia cells Tekijä Pedro Casado, Edmund H. Wilkes, Farideh Miraki‐Moud, Marym Mohammad Hadi, Ana Rio‐Machín, Vinothini Rajeeve, Rebecca Pike, Sameena Iqbal, Santiago Marfà, Nicholas Lea, Steven Best, John G. Gribben, Jude Fitzgibbon, Pedro R. Cutillas

    Julkaistu 2018
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  8. 8
    Integrative phosphoproteomics defines two biologically distinct groups of KMT2A rearranged acute myeloid leukaemia with different drug response phenotypes

    Integrative phosphoproteomics defines two biologically distinct groups of KMT2A rearranged acute myeloid leukaemia with different drug response phenotypes Tekijä Pedro Casado, Ana Rio‐Machín, Juho J. Miettinen, Findlay Bewicke‐Copley, Kevin Rouault‐Pierre, Szilvia Krizsán, Alun Parsons, Vinothini Rajeeve, Farideh Miraki‐Moud, David Taussig, Csaba Bödör, John G. Gribben, Caroline A. Heckman, Jude Fitzgibbon, Pedro R. Cutillas

    Julkaistu 2023
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  9. 9
    Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion

    Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion Tekijä Ivan Quétier, J. Marshall, Bradley Spencer‐Dene, Sylvie Lachmann, Adele Casamassima, Cláudio A. Franco, Sarah Escuin, Joseph T Worrall, Priththivika Baskaran, Vinothini Rajeeve, Michael Howell, Andrew J. Copp, Gordon Stamp, Ian Rosewell, Pedro R. Cutillas, Holger Gerhardt, Peter J. Parker, Angus J.M. Cameron

    Julkaistu 2016
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  10. 10
    <scp>FAK</scp> activity in cancer‐associated fibroblasts is a prognostic marker and a druggable key metastatic player in pancreatic cancer

    <scp>FAK</scp> activity in cancer‐associated fibroblasts is a prognostic marker and a druggable key metastatic player in pancreatic cancer Tekijä Sonia Zaghdoudi, Emilie Decaup, Ismahane Belhabib, Rémi Samain, Stéphanie Cassant‐Sourdy, Julia Rochotte, Alexia Brunel, David D. Schlaepfer, Jérôme Cros, Cindy Neuzillet, Manon Strehaïano, Amandine Alard, Richard Tomasini, Vinothini Rajeeve, Aurélie Perraud, Muriel Mathonnet, Oliver M.T. Pearce, Yvan Martineau, Stéphane Pyronnet, Corinne Bousquet, Christine Jean

    Julkaistu 2020
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  11. 11
    TGFBI Production by Macrophages Contributes to an Immunosuppressive Microenvironment in Ovarian Cancer

    TGFBI Production by Macrophages Contributes to an Immunosuppressive Microenvironment in Ovarian Cancer Tekijä Laura S.M. Lecker, Chiara Berlato, Eleni Maniati, Robin M. Delaine‐Smith, Oliver M.T. Pearce, Owen Heath, Samuel J. Nichols, Caterina Trevisan, Marián Novak, Jacqueline McDermott, James D. Brenton, Pedro R. Cutillas, Vinothini Rajeeve, Anà Hennino, Ronny Drapkin, Daniela Loessner, Frances R. Balkwill

    Julkaistu 2021
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  12. 12
    Extracellular matrix educates an immunoregulatory tumor macrophage phenotype found in ovarian cancer metastasis

    Extracellular matrix educates an immunoregulatory tumor macrophage phenotype found in ovarian cancer metastasis Tekijä E. H. Puttock, Eleanor J. Tyler, Michela Manni, Eleni Maniati, Charlotte Butterworth, Marcos Burger Ramos, Eleonora Peerani, Priyanka Hirani, V J Gauthier, Ying Liu, Mauro Maniscalco, Vinothini Rajeeve, Pedro R. Cutillas, Caterina Trevisan, Michela Pozzobon, Michelle Lockley, Joseph Rastrick, Heinz Läubli, Ann L. White, Oliver M.T. Pearce

    Julkaistu 2023
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  13. 13
    Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility

    Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility Tekijä Ana Angulo‐Urarte, Pedro Casado, Sandra D. Castillo, Piotr Kobialka, Maria P. Kotini, Ana M. Figueiredo, Pau Castel, Vinothini Rajeeve, Maria Milà‐Guasch, Jaime Millán, Cora Wiesner, Helena Serra, Laia Muixí, Oriol Casanovas, Francesc Viñals, Markus Affolter, Holger Gerhardt, Stephan Huveneers, Heinz‐Georg Belting, Pedro R. Cutillas, Mariona Graupera

    Julkaistu 2018
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  14. 14
    Genome instability is a consequence of transcription deficiency in patients with bone marrow failure harboring biallelic <i>ERCC6L2</i> variants

    Genome instability is a consequence of transcription deficiency in patients with bone marrow failure harboring biallelic <i>ERCC6L2</i> variants Tekijä Hemanth Tummala, Arran Dokal, Amanda J. Walne, Alicia Ellison, Shirleny Cardoso, Saranha Amirthasigamanipillai, Michael Kirwan, Isobel Browne, Jasmin Sidhu, Vinothini Rajeeve, Ana Rio‐Machín, Ahad Al Seraihi, Andrew Duncombe, Matthew Jenner, Owen Smith, Helen Enright, Alice Norton, Tekin Aksu, Namık Yaşar Özbek, Nikolas Pontikos, Pedro R. Cutillas, Inderjeet Dokal, Tom Vulliamy

    Julkaistu 2018
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  15. 15
    RAS-p110α signalling in macrophages is required for effective inflammatory response and resolution of inflammation

    RAS-p110α signalling in macrophages is required for effective inflammatory response and resolution of inflammation Tekijä Alejandro Rosell, Agata Krygowska, Marta Alcón Pérez, Cristina Cuesta, Mathieu-Benoı̂t Voisin, Juan F. De Paz, Héctor Sanz-Fraile, Vinothini Rajeeve, Alberto Berral-González, Ana Carreras‐González, Ottilie Swinyard, Enrique Gabandé‐Rodríguez, Julian Downward, Jordi Alcaraz, Juan Anguíta, María Carmen García-Macías, Javier De Las Rivas, Pedro R. Cutillas, Esther Castellano

    Julkaistu 2025
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  16. 16
    Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition

    Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition Tekijä Marco Sciacovelli, Emanuel Gonçalves, Timothy Isaac Johnson, Vincent Zecchini, Ana S.H. Costa, Edoardo Gaude, Alizée Vercauteren Drubbel, Sebastian J. Theobald, Sandra Riekje Abbo, Maxine Tran, Vinothini Rajeeve, Simone Cardaci, Sarah Foster, Haiyang Yun, Pedro R. Cutillas, Anne Y. Warren, Vincent J. Gnanapragasam, Eyal Gottlieb, Kristian Franze, Brian J.P. Huntly, Eamonn R. Maher, Patrick H. Maxwell, Julio Sáez-Rodríguez, Christian Frezza

    Julkaistu 2016
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  17. 17
    Deconstruction of a Metastatic Tumor Microenvironment Reveals a Common Matrix Response in Human Cancers

    Deconstruction of a Metastatic Tumor Microenvironment Reveals a Common Matrix Response in Human Cancers Tekijä Oliver M.T. Pearce, Robin M. Delaine‐Smith, Eleni Maniati, Sam Nichols, Jun Wang, Steffen Böhm, Vinothini Rajeeve, Dayem Ullah, Probir Chakravarty, Roanne R. Jones, Anne Montfort, Tom Dowe, John G. Gribben, J. Louise Jones, Hemant M. Kocher, Jonathan S. Serody, Benjamin G. Vincent, John T. Connelly, James D. Brenton, Claude Chelala, Pedro R. Cutillas, Michelle Lockley, Conrad Bessant, Martin M. Knight, Frances R. Balkwill

    Julkaistu 2017
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  18. 18
    Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism

    Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism Tekijä Benoît Bilanges, Samira Alliouachene, Wayne Pearce, Daniele Morelli, György Szabadkai, Yuen-Li Chung, Gaëtan Chicanne, Colin Valet, Julia M. Hill, Peter J. Voshol, Lucy Collinson, Christopher J. Peddie, Khaled Ali, Essam Ghazaly, Vinothini Rajeeve, Georgios Trichas, Shankar Srinivas, Claire Chaussade, Rachel S. Salamon, Jonathan Backer, Cheryl L. Scudamore, Maria A. Whitehead, Erin P. Keaney, Leon O. Murphy, Robert K. Semple, Bernard Payrastre, Sharon A. Tooze, Bart Vanhaesebroeck

    Julkaistu 2017
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  19. 19
    Cancer associated fibroblast FAK regulates malignant cell metabolism

    Cancer associated fibroblast FAK regulates malignant cell metabolism Tekijä Fevzi Demircioglu, Jun Wang, Juliana Candido, Ana S.H. Costa, Pedro Casado, Beatriz de Luxán‐Delgado, Louise E. Reynolds, Jesús Gómez-Escudero, Emma Newport, Vinothini Rajeeve, Ann‐Marie Baker, Marina Roy-Luzarraga, Trevor A. Graham, Julie Foster, Yu Wang, James J. Campbell, Rajinder Singh, Penglie Zhang, Thomas J. Schall, Frances R. Balkwill, Jane Sosabowski, Pedro R. Cutillas, Christian Frezza, Patricia Sancho, Kairbaan Hodivala‐Dilke

    Julkaistu 2020
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  20. 20
    Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion

    Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion Tekijä Elizabeth R. Murray, Shinelle Menezes, Jack C. Henry, J.L.D. Williams, Lorena Alba‐Castellón, Priththivika Baskaran, Ivan Quétier, Ami V. Desai, J. Marshall, Ian Rosewell, Marianthi Tatari, Vinothini Rajeeve, Faraz Khan, Jun Wang, Panoraia Kotantaki, Eleanor J. Tyler, Namrata Singh, Claire S. Reader, Edward Carter, Kairbaan Hodivala‐Dilke, Richard Grose, Hemant M. Kocher, Núria Gavara, Oliver M.T. Pearce, Pedro R. Cutillas, John F. Marshall, Angus J.M. Cameron

    Julkaistu 2022
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