検索結果 - Victoria Lock
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1
A phase I pharmacokinetic and pharmacodynamic study of AT7519, a cyclin-dependent kinase inhibitor in patients with refractory solid tumors 著者: Daruka Mahadevan, Ruth Plummer, Matthew Squires, Diane Rensvold, Sandra Kurtin, Chris Pretzinger, Tomislav Dragovich, Joëlla W. Adams, Victoria Lock, Donna-Michelle Smith, D. Von Hoff, Hilary Calvert
出版事項 2011Artigo -
2
A phase I dose escalation study of AT9283, a small molecule inhibitor of aurora kinases, in patients with advanced solid malignancies 著者: Hendrik‐Tobias Arkenau, Ruth Plummer, L. Rhoda Molife, David Olmos, Timothy A. Yap, Matthew Squires, Sara Lewis, Victoria Lock, Murray Yule, John F. Lyons, Hilary Calvert, Ian Judson
出版事項 2011Artigo -
3
AT7867 Is a Potent and Oral Inhibitor of AKT and p70 S6 Kinase That Induces Pharmacodynamic Changes and Inhibits Human Tumor Xenograft Growth 著者: Kyla M. Grimshaw, Lisa-Jane K. Hunter, Timothy A. Yap, Simon P. Heaton, Mike I. Walton, Steven J. Woodhead, Lynsey Fazal, Matthias Reule, Thomas G. Davies, Lisa C. A. Seavers, Victoria Lock, John F. Lyons, Neil T. Thompson, Paul Workman, Michelle D. Garrett
出版事項 2010Artigo -
4
A Phase I Trial of AT9283 (a Selective Inhibitor of Aurora Kinases) in Children and Adolescents with Solid Tumors: A Cancer Research UK Study 著者: Lucas Moreno, Lynley V. Marshall, Andrew D.J. Pearson, Bruce Morland, Martin Elliott, Quentin Campbell‐Hewson, Guy Makin, Sarah Halford, Gary D Acton, Philip Ross, Shamim Kazmi-Stokes, Victoria Lock, Ana Isabel Enríquez Rodríguez, John F. Lyons, Alan V. Boddy, Melanie J. Griffin, Murray Yule, Darren Hargrave
出版事項 2014Artigo
関連主題
Biology
Internal medicine
Kinase
Medicine
Oncology
Pharmacology
Adverse effect
Biochemistry
Cancer
Cancer research
Cell biology
Chemistry
Pharmacodynamics
Pharmacokinetics
Tolerability
Toxicity
Astrobiology
Bioavailability
Cell cycle
Cell growth
Clinical trial
Cyclin-dependent kinase
Febrile neutropenia
Gastroenterology
Gene
Genetics
Growth inhibition
Histone
Histone H3
Mucositis