検索結果 - Vazquez, Francisca

The Cancer Dependency Map enables drug mechanism‐of‐action investigations 著者: Vazquez, Francisca, Boehm, Jesse S

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Bridging the gap between cancer cell line models and tumours using gene expression data 著者: Noorbakhsh, Javad, Vazquez, Francisca, McFarland, James M.

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Phosphorylation of the PTEN Tail Regulates Protein Stability and Function 著者: Vazquez, Francisca, Ramaswamy, Shivapriya, Nakamura, Noriaki, Sellers, William R.

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Computational estimation of quality and clinical relevance of cancer cell lines 著者: Trastulla, Lucia, Noorbakhsh, Javad, Vazquez, Francisca, McFarland, James, Iorio, Francesco

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A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN 著者: Rahdar, Meghdad, Inoue, Takanari, Meyer, Tobias, Zhang, Jin, Vazquez, Francisca, Devreotes, Peter N.

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Forkhead Transcription Factors Are Critical Effectors of Cell Death and Cell Cycle Arrest Downstream of PTEN 著者: Nakamura, Noriaki, Ramaswamy, Shivapriya, Vazquez, Francisca, Signoretti, Sabina, Loda, Massimo, Sellers, William R.

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Tumor suppressor PTEN acts through dynamic interaction with the plasma membrane 著者: Vazquez, Francisca, Matsuoka, Satomi, Sellers, William R., Yanagida, Toshio, Ueda, Masahiro, Devreotes, Peter N.

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Regulation of G(1) progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway 著者: Ramaswamy, Shivapriya, Nakamura, Noriaki, Vazquez, Francisca, Batt, David B., Perera, Sauni, Roberts, Thomas M., Sellers, William R.

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A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: determinants of gene silencing for use in cell-based screens 著者: Hsieh, Andrew C., Bo, Ronghai, Manola, Judith, Vazquez, Francisca, Bare, Olivia, Khvorova, Anastasia, Scaringe, Stephen, Sellers, William R.

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A PGC1α-mediated transcriptional axis suppresses melanoma metastasis 著者: Luo, Chi, Lim, Ji-Hong, Lee, Yoonjin, Granter, Scott R., Thomas, Ajith, Vazquez, Francisca, Widlund, Hans R., Puigserver, Pere

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H3K27me3-mediated PGC1α gene silencing promotes melanoma invasion through WNT5A and YAP 著者: Luo, Chi, Balsa, Eduardo, Perry, Elizabeth A., Liang, Jiaxin, Tavares, Clint D., Vazquez, Francisca, Widlund, Hans R., Puigserver, Pere

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Complementary information derived from CRISPR Cas9 mediated gene deletion and suppression 著者: Rosenbluh, Joseph, Xu, Han, Harrington, William, Gill, Stanley, Wang, Xiaoxing, Vazquez, Francisca, Root, David E., Tsherniak, Aviad, Hahn, William C.

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Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFR 著者: Zhang, Hongbing, Cicchetti, Gregor, Onda, Hiroaki, Koon, Henry B., Asrican, Kirsten, Bajraszewski, Natalia, Vazquez, Francisca, Carpenter, Christopher L., Kwiatkowski, David J.

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Residual Complexes Containing SMARCA2 (BRM) Underlie the Oncogenic Drive of SMARCA4 (BRG1) Mutation 著者: Wilson, Boris G., Helming, Katherine C., Wang, Xiaofeng, Kim, Youngha, Vazquez, Francisca, Jagani, Zainab, Hahn, William C., Roberts, Charles W. M.

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Global computational alignment of tumor and cell line transcriptional profiles 著者: Warren, Allison, Chen, Yejia, Jones, Andrew, Shibue, Tsukasa, Hahn, William C., Boehm, Jesse S., Vazquez, Francisca, Tsherniak, Aviad, McFarland, James M.

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Chronos: a cell population dynamics model of CRISPR experiments that improves inference of gene fitness effects 著者: Dempster, Joshua M., Boyle, Isabella, Vazquez, Francisca, Root, David E., Boehm, Jesse S., Hahn, William C., Tsherniak, Aviad, McFarland, James M.

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The EMT regulator ZEB2 is a novel dependency of human and murine acute myeloid leukemia 著者: Li, Hubo, Mar, Brenton G., Zhang, Huadi, Puram, Rishi V., Vazquez, Francisca, Weir, Barbara A., Hahn, William C., Ebert, Benjamin, Pellman, David

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Evaluation of Circulating Tumor Cells and Related Events as Prognostic Factors and Surrogate Biomarkers in Advanced NSCLC Patients Receiving First-Line Systemic Treatment 著者: Muinelo-Romay, Laura, Vieito, Maria, Abalo, Alicia, Alonso Nocelo, Marta, Barón, Francisco, Anido, Urbano, Brozos, Elena, Vázquez, Francisca, Aguín, Santiago, Abal, Miguel, López López, Rafael

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Sparse dictionary learning recovers pleiotropy from human cell fitness screens 著者: Pan, Joshua, Kwon, Jason J., Talamas, Jessica A., Borah, Ashir A., Vazquez, Francisca, Boehm, Jesse S., Tsherniak, Aviad, Zitnik, Marinka, McFarland, James M., Hahn, William C.

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PGC1α Expression Defines a Subset of Human Melanoma Tumors with Increased Mitochondrial Capacity and Resistance to Oxidative Stress 著者: Vazquez, Francisca, Lim, Ji-Hong, Chim, Helen, Bhalla, Kavita, Girnun, Geoff, Pierce, Kerry, Clish, Clary B., Granter, Scott R., Widlund, Hans R., Spiegelman, Bruce M., Puigserver, Pere

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