檢索結果 - Vasanthi S. Viswanathan

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  1. 1
    Diacylfuroxans Are Masked Nitrile Oxides That Inhibit GPX4 Covalently

    Diacylfuroxans Are Masked Nitrile Oxides That Inhibit GPX4 Covalently 由 John K. Eaton, Richard A. Ruberto, Anneke Kramm, Vasanthi S. Viswanathan, Stuart L. Schreiber

    出版 2019
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  2. 2
    Structure–activity relationships of GPX4 inhibitor warheads

    Structure–activity relationships of GPX4 inhibitor warheads 由 John K. Eaton, Laura Furst, Luke L. Cai, Vasanthi S. Viswanathan, Stuart L. Schreiber

    出版 2020
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  3. 3
    Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162

    Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162 由 Dieter Moosmayer, A. Hilpmann, Jutta Hoffmann, Lennart Schnirch, Katja Zimmermann, Volker Badock, Laura Furst, John K. Eaton, Vasanthi S. Viswanathan, Stuart L. Schreiber, Stefan Gradl, R.C. Hillig

    出版 2021
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  4. 4
    Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

    Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition 由 Matthew J. Hangauer, Vasanthi S. Viswanathan, Matthew J. Ryan, Dhruv Bole, John K. Eaton, Alexandre Matov, Jacqueline Galeas, Harshil Dhruv, Michael E. Berens, Stuart L. Schreiber, Frank McCormick, Michael T. McManus

    出版 2017
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  5. 5
    Regulation of Ferroptotic Cancer Cell Death by GPX4

    Regulation of Ferroptotic Cancer Cell Death by GPX4 由 Wan Seok Yang, Rohitha Sriramaratnam, Matthew Welsch, Kaoru Shimada, Rachid Skouta, Vasanthi S. Viswanathan, Jaime H. Cheah, Paul A. Clemons, Alykhan F. Shamji, Clary B. Clish, Lewis M. Brown, Albert W. Girotti, Virginia W. Cornish, Stuart L. Schreiber, Brent R. Stockwell

    出版 2014
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  6. 6
    A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis

    A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis 由 Yilong Zou, Michael J. Palte, Amy Deik, Haoxin Li, John K. Eaton, Wenyu Wang, Yuen‐Yi Tseng, Rebecca Deasy, Maria Kost‐Alimova, Vlado Dančík, Elizaveta S. Leshchiner, Vasanthi S. Viswanathan, Sabina Signoretti, Toni K. Choueiri, Jesse S. Boehm, Bridget K. Wagner, John G. Doench, Clary B. Clish, Paul A. Clemons, Stuart L. Schreiber

    出版 2019
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  7. 7
    Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles

    Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles 由 John K. Eaton, Laura Furst, Richard A. Ruberto, Dieter Moosmayer, A. Hilpmann, Matthew J. Ryan, Katja Zimmermann, Luke L. Cai, Michael Niehues, Volker Badock, Anneke Kramm, Sixun Chen, R.C. Hillig, Paul A. Clemons, Stefan Gradl, Claire Montagnon, Kiel E. Lazarski, Sven Christian, Besnik Bajrami, Roland Neuhaus, Ashley Eheim, Vasanthi S. Viswanathan, Stuart L. Schreiber

    出版 2020
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  8. 8
    DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with<i>In Silico</i>Analysis to Identify Novel Therapeutic Targets

    DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with<i>In Silico</i>Analysis to Identify Novel Therapeutic Targets 由 Allison R. Hanaford, Tenley C. Archer, Antoinette Price, Ulf D. Kahlert, Jarek Maciaczyk, Guido Nikkhah, Jong Wook Kim, Tobias Ehrenberger, Paul A. Clemons, Vlado Dančík, Brinton Seashore‐Ludlow, Vasanthi S. Viswanathan, Michelle L. Stewart, Matthew G. Rees, Alykhan Shamji, Stuart L. Schreiber, Ernest Fraenkel, Scott L. Pomeroy, Jill P. Mesirov, Pablo Tamayo, Charles G. Eberhart, Eric H. Raabe

    出版 2016
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  9. 9
    Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers

    Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers 由 Rushdia Z. Yusuf, Borja Sáez, Azeem Sharda, Nick van Gastel, Vionnie W.C. Yu, Ninib Baryawno, Elizabeth W. Scadden, Sanket S. Acharya, Shrikanta Chattophadhyay, Cherrie Huang, Vasanthi S. Viswanathan, Dana S'aulis, Julien Cobert, David B. Sykes, Mark A. Keibler, Sudeshna Das, John N. Hutchinson, Michael Churchill, Siddhartha Mukherjee, Dongjun Lee, François Mercier, John G. Doench, Lars Bullinger, David J. Logan, Stuart L. Schreiber, Gregory Stephanopoulos, William B. Rizzo, David T. Scadden

    出版 2020
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  10. 10
    ROS Induction Targets Persister Cancer Cells with Low Metabolic Activity in NRAS-Mutated Melanoma

    ROS Induction Targets Persister Cancer Cells with Low Metabolic Activity in NRAS-Mutated Melanoma 由 Ossia M. Eichhoff, Corinne I. Stoffel, Jan Käsler, Luzia Briker, Patrick Turko, Gergely Karsai, Nina Zila, Verena Paulitschke, Phil F. Cheng, Alexander Leitner, Andrea Bileck, Nicola Zamboni, Anja Irmisch, Zsolt Balázs, Aizhan Tastanova, Susana Pascoal, Pål Johansen, Rebekka Wegmann, Julien Mena, Alaa Othman, Vasanthi S. Viswanathan, Judith Wenzina, Andrea Aloia, Annalisa Saltari, Andreas Dzung, Michael Krauthammer, Stuart L. Schreiber, Thorsten Hornemann, Martin Distel, Berend Snijder, Reinhard Dummer, Mitchell P. Levesque

    出版 2023
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  11. 11
    Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

    Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway 由 Vasanthi S. Viswanathan, Matthew J. Ryan, Harshil Dhruv, Shubhroz Gill, Ossia M. Eichhoff, Brinton Seashore‐Ludlow, Samuel D. Kaffenberger, John K. Eaton, Kaoru Shimada, Andrew J. Aguirre, Srinivas R. Viswanathan, Shrikanta Chattopadhyay, Pablo Tamayo, Wan Seok Yang, Matthew G. Rees, Sixun Chen, Žarko Bošković, Sarah Javaid, Cherrie Huang, Xiaoyun Wu, Yuen-Yi Tseng, Elisabeth Roider, Dong Gao, James M. Cleary, Brian M. Wolpin, Jill P. Mesirov, Daniel A. Haber, Jeffrey A. Engelman, Jesse S. Boehm, Joanne Kotz, Cindy Hon, Yu Chen, William C. Hahn, Mitchell P. Levesque, John G. Doench, Michael E. Berens, Alykhan F. Shamji, Paul A. Clemons, Brent R. Stockwell, Stuart L. Schreiber

    出版 2017
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  12. 12
    An expanded universe of cancer targets

    An expanded universe of cancer targets 由 William C. Hahn, Joel S. Bader, Theodore P. Braun, Andrea Califano, Paul A. Clemons, Brian J. Druker, Andrew J. Ewald, Haian Fu, Subhashini Jagu, Christopher J. Kemp, William Kim, Calvin J. Kuo, Michael T. McManus, Gordon B. Mills, Xiulei Mo, Nidhi Sahni, Stuart L. Schreiber, Jessica A. Talamas, Pablo Tamayo, Jeffrey W. Tyner, Bridget K. Wagner, William A. Weiss, Daniela S. Gerhard, Vlado Dančík, Shubhroz Gill, Bruce K. Hua, Tanaz Sharifnia, Vasanthi S. Viswanathan, Yilong Zou, Filemon S. Dela Cruz, Andrew L. Kung, Brent R. Stockwell, Jesse S. Boehm, Josh Dempster, Robert T. Manguso, Francisca Vázquez, Lee Cooper, Yuhong Du, Andrei A. Ivanov, Sagar Lonial, Carlos S. Moreno, Qiankun Niu, Taofeek K. Owonikoko, Suresh S. Ramalingam, Matthew A. Reyna, Wei Zhou, Carla Grandori, Ilya Shmulevich, Elizabeth M. Swisher, Jitong Cai, Isaac S. Chan, Matthew Dunworth, Yuchen Ge, Dan Georgess, Eloïse M. Grasset, Elodie Henriet, Hildur Knútsdóttir, Michael G. Lerner, Veena Padmanaban, Matthew C. Perrone, Yasir Suhail, Yohannes Tsehay, Manisha Warrier, Quin Morrow, Tamilla Nechiporuk, Nicola Long, Jennifer N. Saultz, Andy Kaempf, Jessica Minnier, Cristina E. Tognon, Stephen E. Kurtz, Anupriya Agarwal, Jordana F. Brown, Kevin Watanabe‐Smith, Tania Q. Vu, Thomas Jacob, Yunqi Yan, Bridget A. Robinson, Evan Lind, Yoko Kosaka, Emek Demir, Joseph Estabrook, Michael Grzadkowski, Olga Nikolova, Ken Chen, Ben Deneen, Han Liang, Michael C. Bassik, Asmita Bhattacharya, Kevin Brennan, Christina Curtis, Olivier Gevaert, Hanlee P. Ji, Kasper Karlsson, Kremena Karagyozova, Yuan‐Hung Lo, Katherine Liu, Michitaka Nakano, Anuja Sathe, Amber R. Smith

    出版 2021
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