תוצאות חיפוש - Vasanthakumar, Aparna

Selective inhibition of the citrate-to-isocitrate reaction of cytosolic aconitase by phosphomimetic mutation of serine-711 מאת Pitula, Joseph S., Deck, Kathryn M., Clarke, Stephen L., Anderson, Sheila A., Vasanthakumar, Aparna, Eisenstein, Richard S.

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Association of peripheral blood DNA methylation level with Alzheimer’s disease progression מאת Li, Qingqin S., Vasanthakumar, Aparna, Davis, Justin W., Idler, Kenneth B., Nho, Kwangsik, Waring, Jeffrey F., Saykin , Andrew J.

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Evidence That Phosphorylation of Iron Regulatory Protein 1 at Serine 138 Destabilizes the [4Fe-4S] Cluster in Cytosolic Aconitase by Enhancing 4Fe-3Fe Cycling מאת Deck, Kathryn M., Vasanthakumar, Aparna, Anderson, Sheila A., Goforth, Jeremy B., Kennedy, M. Claire, Antholine, William E., Eisenstein, Richard S.

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Differential translational control of 5’ IRE-containing mRNA in response to dietary iron deficiency and acute iron overload מאת Garza, Kerry R., Clarke, Stephen L., Ho, Yi-Hsuan, Bruss, Matthew D., Vasanthakumar, Aparna, Anderson, Sheila A., Eisenstein, Richard S.

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Reduced ITPase activity and favorable IL28B genetic variant protect against ribavirin-induced anemia in interferon-free regimens מאת Vasanthakumar, Aparna, Davis, Justin W., Abunimeh, Manal, Söderholm, Jonas, Zha, Jiuhong, Dumas, Emily O., Cohen, Daniel E., Waring, Jeffrey F., Lagging, Martin

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Iron-responsive degradation of iron-regulatory protein 1 does not require the Fe–S cluster מאת Clarke, Stephen L, Vasanthakumar, Aparna, Anderson, Sheila A, Pondarré, Corinne, Koh, Cheryl M, Deck, Kathryn M, Pitula, Joseph S, Epstein, Charles J, Fleming, Mark D, Eisenstein, Richard S

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Effects of TET2 mutations on DNA methylation in chronic myelomonocytic leukemia מאת Yamazaki, Jumpei, Taby, Rodolphe, Vasanthakumar, Aparna, Macrae, Trisha, Ostler, Kelly R, Shen, Lanlan, Kantarjian, Hagop M, Estecio, Marcos R, Jelinek, Jaroslav, Godley, Lucy A, Issa, Jean-Pierre J

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2-Hydroxyglutarate in IDH mutant acute myeloid leukemia: predicting patient responses, minimal residual disease and correlations with methylcytosine and hydroxymethylcytosine level... מאת Pollyea, Daniel A., Kohrt, Holbrook E., Zhang, Bing, Zehnder, James, Schenkein, David, Fantin, Valeria, Straley, Kimberly, Vasanthakumar, Aparna, Abdel-Wahab, Omar, Levine, Ross, Godley, Lucy A., Medeiros, Bruno C.

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Dnmt3b is a haploinsufficient tumor suppressor gene in Myc-induced lymphomagenesis מאת Vasanthakumar, Aparna, Lepore, Janet B., Zegarek, Matthew H., Kocherginsky, Masha, Singh, Mahi, Davis, Elizabeth M., Link, Petra A., Anastasi, John, Le Beau, Michelle M., Karpf, Adam R., Godley, Lucy A.

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TET1-Mediated Hydroxymethylation Facilitates Hypoxic Gene Induction in Neuroblastoma מאת Mariani, Christopher J., Vasanthakumar, Aparna, Madzo, Jozef, Yesilkanal, Ali, Bhagat, Tushar, Yu, Yiting, Bhattacharyya, Sanchari, Wenger, Roland H., Cohn, Susan L., Nanduri, Jayasri, Verma, Amit, Prabhakar, Nanduri R., Godley, Lucy A.

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DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID מאת Dominguez, Pilar M., Teater, Matt, Chambwe, Nyasha, Kormaksson, Matthias, Redmond, David, Ishii, Jennifer, Vuong, Bao, Chaudhuri, Jayanta, Melnick, Ari, Vasanthakumar, Aparna, Godley, Lucy A., Papavasiliou, F Nina, Elemento, Olivier, Shaknovich, Rita

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Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer מאת Bhattacharyya, Sanchari, Yu, Yiting, Suzuki, Masako, Campbell, Nathaniel, Mazdo, Jozef, Vasanthakumar, Aparna, Bhagat, Tushar D., Nischal, Sangeeta, Christopeit, Maximilian, Parekh, Samir, Steidl, Ulrich, Godley, Lucy, Maitra, Anirban, Greally, John M., Verma, Amit

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5-hmC–mediated epigenetic dynamics during postnatal neurodevelopment and aging מאת Szulwach, Keith E, Li, Xuekun, Li, Yujing, Song, Chun-Xiao, Wu, Hao, Dai, Qing, Irier, Hasan, Upadhyay, Anup K, Gearing, Marla, Levey, Allan I, Vasanthakumar, Aparna, Godley, Lucy A, Chang, Qiang, Cheng, Xiaodong, He, Chuan, Jin, Peng

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DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis מאת Shah, Mrinal Y., Vasanthakumar, Aparna, Barnes, Natalie Y., Figueroa, Maria E., Kamp, Anna, Hendrick, Christopher, Ostler, Kelly R., Davis, Elizabeth M., Lin, Shang, Anastasi, John, Le Beau, Michelle M., Moskowitz, Ivan, Melnick, Ari, Pytel, Peter, Godley, Lucy A.

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TET2 mutations affect non-CpG island DNA methylation at enhancers and transcription factor binding sites in chronic myelomonocytic leukemia מאת Yamazaki, Jumpei, Jelinek, Jaroslav, Lu, Yue, Cesaroni, Matteo, Madzo, Jozef, Neumann, Frank, He, Rong, Taby, Rodolphe, Vasanthakumar, Aparna, Macrae, Trisha, Ostler, Kelly R., Kantarjian, Hagop M., Liang, Shoudan, Estecio, Marcos R., Godley, Lucy A., Issa, Jean-Pierre J.

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DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation מאת Shaknovich, Rita, Cerchietti, Leandro, Tsikitas, Lucas, Kormaksson, Matthias, De, Subhajyoti, Figueroa, Maria E., Ballon, Gianna, Yang, Shao Ning, Weinhold, Nils, Reimers, Mark, Clozel, Thomas, Luttrop, Karin, Ekstrom, Tomas J., Frank, Jared, Vasanthakumar, Aparna, Godley, Lucy A., Michor, Franziska, Elemento, Olivier, Melnick, Ari

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Dnmt3a is essential for hematopoietic stem cell differentiation מאת Challen, Grant A, Sun, Deqiang, Jeong, Mira, Luo, Min, Jelinek, Jaroslav, Berg, Jonathan S, Bock, Christoph, Vasanthakumar, Aparna, Gu, Hongcang, Xi, Yuanxin, Liang, Shoudan, Lu, Yue, Darlington, Gretchen J, Meissner, Alexander, Issa, Jean-Pierre J, Godley, Lucy A, Li, Wei, Goodell, Margaret A

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Truncated DNMT3B isoform DNMT3B7 suppresses growth, induces differentiation, and alters DNA methylation in human neuroblastoma מאת Ostler, Kelly R., Yang, Qiwei, Looney, Timothy J., Zhang, Li, Vasanthakumar, Aparna, Tian, Yufeng, Kocherginsky, Masha, Raimondi, Stacey L., DeMaio, Jessica G., Salwen, Helen R., Gu, Song, Chlenski, Alexandre, Naranjo, Arlene, Gill, Amy, Peddinti, Radhika, Lahn, Bruce T., Cohn, Susan L., Godley, Lucy A.

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Harnessing peripheral DNA methylation differences in the Alzheimer’s Disease Neuroimaging Initiative (ADNI) to reveal novel biomarkers of disease מאת Vasanthakumar, Aparna, Davis, Justin W., Idler, Kenneth, Waring, Jeffrey F., Asque, Elizabeth, Riley-Gillis, Bridget, Grosskurth, Shaun, Srivastava, Gyan, Kim, Sungeun, Nho, Kwangsik, Nudelman, Kelly N. H., Faber, Kelley, Sun, Yu, Foroud, Tatiana M., Estrada, Karol, Apostolova, Liana G., Li, Qingqin S., Saykin, Andrew J.

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Recurrent Somatic TET2 Mutations in Normal Elderly Individuals With Clonal Hematopoiesis מאת Busque, Lambert, Patel, Jay P., Figueroa, Maria, Vasanthakumar, Aparna, Provost, Sylvie, Hamilou, Zineb, Mollica, Luigina, Li, Juan, Viale, Agnes, Heguy, Adriana, Hassimi, Maryam, Socci, Nicholas, Bhatt, Parva K., Gonen, Mithat, Mason, Christopher E., Melnick, Ari, Godley, Lucy A., Brennan, Cameron, Abdel-Wahab, Omar, Levine, Ross L.

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