Canlyniadau Chwilio - Vasanthakumar, Aparna

Selective inhibition of the citrate-to-isocitrate reaction of cytosolic aconitase by phosphomimetic mutation of serine-711 gan Pitula, Joseph S., Deck, Kathryn M., Clarke, Stephen L., Anderson, Sheila A., Vasanthakumar, Aparna, Eisenstein, Richard S.

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Association of peripheral blood DNA methylation level with Alzheimer’s disease progression gan Li, Qingqin S., Vasanthakumar, Aparna, Davis, Justin W., Idler, Kenneth B., Nho, Kwangsik, Waring, Jeffrey F., Saykin , Andrew J.

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Evidence That Phosphorylation of Iron Regulatory Protein 1 at Serine 138 Destabilizes the [4Fe-4S] Cluster in Cytosolic Aconitase by Enhancing 4Fe-3Fe Cycling gan Deck, Kathryn M., Vasanthakumar, Aparna, Anderson, Sheila A., Goforth, Jeremy B., Kennedy, M. Claire, Antholine, William E., Eisenstein, Richard S.

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Differential translational control of 5’ IRE-containing mRNA in response to dietary iron deficiency and acute iron overload gan Garza, Kerry R., Clarke, Stephen L., Ho, Yi-Hsuan, Bruss, Matthew D., Vasanthakumar, Aparna, Anderson, Sheila A., Eisenstein, Richard S.

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Reduced ITPase activity and favorable IL28B genetic variant protect against ribavirin-induced anemia in interferon-free regimens gan Vasanthakumar, Aparna, Davis, Justin W., Abunimeh, Manal, Söderholm, Jonas, Zha, Jiuhong, Dumas, Emily O., Cohen, Daniel E., Waring, Jeffrey F., Lagging, Martin

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Iron-responsive degradation of iron-regulatory protein 1 does not require the Fe–S cluster gan Clarke, Stephen L, Vasanthakumar, Aparna, Anderson, Sheila A, Pondarré, Corinne, Koh, Cheryl M, Deck, Kathryn M, Pitula, Joseph S, Epstein, Charles J, Fleming, Mark D, Eisenstein, Richard S

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Effects of TET2 mutations on DNA methylation in chronic myelomonocytic leukemia gan Yamazaki, Jumpei, Taby, Rodolphe, Vasanthakumar, Aparna, Macrae, Trisha, Ostler, Kelly R, Shen, Lanlan, Kantarjian, Hagop M, Estecio, Marcos R, Jelinek, Jaroslav, Godley, Lucy A, Issa, Jean-Pierre J

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2-Hydroxyglutarate in IDH mutant acute myeloid leukemia: predicting patient responses, minimal residual disease and correlations with methylcytosine and hydroxymethylcytosine level... gan Pollyea, Daniel A., Kohrt, Holbrook E., Zhang, Bing, Zehnder, James, Schenkein, David, Fantin, Valeria, Straley, Kimberly, Vasanthakumar, Aparna, Abdel-Wahab, Omar, Levine, Ross, Godley, Lucy A., Medeiros, Bruno C.

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Dnmt3b is a haploinsufficient tumor suppressor gene in Myc-induced lymphomagenesis gan Vasanthakumar, Aparna, Lepore, Janet B., Zegarek, Matthew H., Kocherginsky, Masha, Singh, Mahi, Davis, Elizabeth M., Link, Petra A., Anastasi, John, Le Beau, Michelle M., Karpf, Adam R., Godley, Lucy A.

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TET1-Mediated Hydroxymethylation Facilitates Hypoxic Gene Induction in Neuroblastoma gan Mariani, Christopher J., Vasanthakumar, Aparna, Madzo, Jozef, Yesilkanal, Ali, Bhagat, Tushar, Yu, Yiting, Bhattacharyya, Sanchari, Wenger, Roland H., Cohn, Susan L., Nanduri, Jayasri, Verma, Amit, Prabhakar, Nanduri R., Godley, Lucy A.

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DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID gan Dominguez, Pilar M., Teater, Matt, Chambwe, Nyasha, Kormaksson, Matthias, Redmond, David, Ishii, Jennifer, Vuong, Bao, Chaudhuri, Jayanta, Melnick, Ari, Vasanthakumar, Aparna, Godley, Lucy A., Papavasiliou, F Nina, Elemento, Olivier, Shaknovich, Rita

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Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer gan Bhattacharyya, Sanchari, Yu, Yiting, Suzuki, Masako, Campbell, Nathaniel, Mazdo, Jozef, Vasanthakumar, Aparna, Bhagat, Tushar D., Nischal, Sangeeta, Christopeit, Maximilian, Parekh, Samir, Steidl, Ulrich, Godley, Lucy, Maitra, Anirban, Greally, John M., Verma, Amit

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5-hmC–mediated epigenetic dynamics during postnatal neurodevelopment and aging gan Szulwach, Keith E, Li, Xuekun, Li, Yujing, Song, Chun-Xiao, Wu, Hao, Dai, Qing, Irier, Hasan, Upadhyay, Anup K, Gearing, Marla, Levey, Allan I, Vasanthakumar, Aparna, Godley, Lucy A, Chang, Qiang, Cheng, Xiaodong, He, Chuan, Jin, Peng

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DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis gan Shah, Mrinal Y., Vasanthakumar, Aparna, Barnes, Natalie Y., Figueroa, Maria E., Kamp, Anna, Hendrick, Christopher, Ostler, Kelly R., Davis, Elizabeth M., Lin, Shang, Anastasi, John, Le Beau, Michelle M., Moskowitz, Ivan, Melnick, Ari, Pytel, Peter, Godley, Lucy A.

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TET2 mutations affect non-CpG island DNA methylation at enhancers and transcription factor binding sites in chronic myelomonocytic leukemia gan Yamazaki, Jumpei, Jelinek, Jaroslav, Lu, Yue, Cesaroni, Matteo, Madzo, Jozef, Neumann, Frank, He, Rong, Taby, Rodolphe, Vasanthakumar, Aparna, Macrae, Trisha, Ostler, Kelly R., Kantarjian, Hagop M., Liang, Shoudan, Estecio, Marcos R., Godley, Lucy A., Issa, Jean-Pierre J.

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DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B-cell differentiation gan Shaknovich, Rita, Cerchietti, Leandro, Tsikitas, Lucas, Kormaksson, Matthias, De, Subhajyoti, Figueroa, Maria E., Ballon, Gianna, Yang, Shao Ning, Weinhold, Nils, Reimers, Mark, Clozel, Thomas, Luttrop, Karin, Ekstrom, Tomas J., Frank, Jared, Vasanthakumar, Aparna, Godley, Lucy A., Michor, Franziska, Elemento, Olivier, Melnick, Ari

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Dnmt3a is essential for hematopoietic stem cell differentiation gan Challen, Grant A, Sun, Deqiang, Jeong, Mira, Luo, Min, Jelinek, Jaroslav, Berg, Jonathan S, Bock, Christoph, Vasanthakumar, Aparna, Gu, Hongcang, Xi, Yuanxin, Liang, Shoudan, Lu, Yue, Darlington, Gretchen J, Meissner, Alexander, Issa, Jean-Pierre J, Godley, Lucy A, Li, Wei, Goodell, Margaret A

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Truncated DNMT3B isoform DNMT3B7 suppresses growth, induces differentiation, and alters DNA methylation in human neuroblastoma gan Ostler, Kelly R., Yang, Qiwei, Looney, Timothy J., Zhang, Li, Vasanthakumar, Aparna, Tian, Yufeng, Kocherginsky, Masha, Raimondi, Stacey L., DeMaio, Jessica G., Salwen, Helen R., Gu, Song, Chlenski, Alexandre, Naranjo, Arlene, Gill, Amy, Peddinti, Radhika, Lahn, Bruce T., Cohn, Susan L., Godley, Lucy A.

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Harnessing peripheral DNA methylation differences in the Alzheimer’s Disease Neuroimaging Initiative (ADNI) to reveal novel biomarkers of disease gan Vasanthakumar, Aparna, Davis, Justin W., Idler, Kenneth, Waring, Jeffrey F., Asque, Elizabeth, Riley-Gillis, Bridget, Grosskurth, Shaun, Srivastava, Gyan, Kim, Sungeun, Nho, Kwangsik, Nudelman, Kelly N. H., Faber, Kelley, Sun, Yu, Foroud, Tatiana M., Estrada, Karol, Apostolova, Liana G., Li, Qingqin S., Saykin, Andrew J.

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Recurrent Somatic TET2 Mutations in Normal Elderly Individuals With Clonal Hematopoiesis gan Busque, Lambert, Patel, Jay P., Figueroa, Maria, Vasanthakumar, Aparna, Provost, Sylvie, Hamilou, Zineb, Mollica, Luigina, Li, Juan, Viale, Agnes, Heguy, Adriana, Hassimi, Maryam, Socci, Nicholas, Bhatt, Parva K., Gonen, Mithat, Mason, Christopher E., Melnick, Ari, Godley, Lucy A., Brennan, Cameron, Abdel-Wahab, Omar, Levine, Ross L.

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