Bilaketaren emaitzak - Varela, Ignacio

Intratumoral heterogeneity and clonal evolution in blood malignancies and solid tumors nork Varela, Ignacio, Menendez, Pablo, Sanjuan-Pla, Alejandra

Testu osoa Testu osoa Testu osoa

Identification, functional expression and enzymic analysis of two distinct CaaX proteases from Caenorhabditis elegans. nork Cadiñanos, Juan, Schmidt, Walter K, Fueyo, Antonio, Varela, Ignacio, López-Otín, Carlos, Freije, José M P

Testu osoa Testu osoa Testu osoa

Clonal haematopoiesis is not prevalent in survivors of childhood cancer nork Collord, Grace, Park, Naomi, Podestà, Marina, Dagnino, Monica, Cilloni, Daniela, Jones, David, Varela, Ignacio, Frassoni, Francesco, Vassiliou, George S.

Testu osoa Testu osoa Testu osoa

Identification of a germline F692L drug resistance variant in cis with Flt3-internal tandem duplication in knock-in mice nork Dovey, Oliver M., Chen, Bin, Mupo, Annalisa, Friedrich, Mathias, Grove, Carolyn S., Cooper, Jonathan L., Lee, Benjamin, Varela, Ignacio, Huang, Yue, Vassiliou, George S.

Testu osoa Testu osoa Testu osoa

Aging and chronic DNA damage response activate a regulatory pathway involving miR-29 and p53 nork Ugalde, Alejandro P, Ramsay, Andrew J, de la Rosa, Jorge, Varela, Ignacio, Mariño, Guillermo, Cadiñanos, Juan, Lu, Jun, Freije, José MP, López-Otín, Carlos

Testu osoa Testu osoa Testu osoa

Sin3b Interacts with Myc and Decreases Myc Levels nork Garcia-Sanz, Pablo, Quintanilla, Andrea, Lafita, M. Carmen, Moreno-Bueno, Gema, García-Gutierrez, Lucia, Tabor, Vedrana, Varela, Ignacio, Shiio, Yuzuru, Larsson, Lars-Gunnar, Portillo, Francisco, Leon, Javier

Testu osoa Testu osoa Testu osoa

A functional variant of TLR10 modifies the activity of NFkB and may help predict a worse prognosis in patients with rheumatoid arthritis nork Torices, Silvia, Julia, Antonio, Muñoz, Pedro, Varela, Ignacio, Balsa, Alejandro, Marsal, Sara, Fernández-Nebro, Antonio, Blanco, Francisco, López-Hoyos, Marcos, Martinez-Taboada, Víctor, Fernández-Luna, Jose L.

Testu osoa Testu osoa Testu osoa

Somatic Mutations Reveal Lineage Relationships and Age-Related Mutagenesis in Human Hematopoiesis nork Osorio, Fernando G., Rosendahl Huber, Axel, Oka, Rurika, Verheul, Mark, Patel, Sachin H., Hasaart, Karlijn, de la Fonteijne, Lisanne, Varela, Ignacio, Camargo, Fernando D., van Boxtel, Ruben

Testu osoa Testu osoa Testu osoa

Nuclear envelope defects cause stem cell dysfunction in premature-aging mice nork Espada, Jesús, Varela, Ignacio, Flores, Ignacio, Ugalde, Alejandro P., Cadiñanos, Juan, Pendás, Alberto M., Stewart, Colin L., Tryggvason, Karl, Blasco, María A., Freije, José M.P., López-Otín, Carlos

Testu osoa Testu osoa Testu osoa

JAK2 V617F hematopoietic clones are present several years prior to MPN diagnosis and follow different expansion kinetics nork McKerrell, Thomas, Park, Naomi, Chi, Jianxiang, Collord, Grace, Moreno, Thaidy, Ponstingl, Hannes, Dias, Joao, Gerasimou, Petroula, Melanthiou, Kiki, Prokopiou, Chrystalla, Antoniades, Marios, Varela, Ignacio, Costeas, Paul A., Vassiliou, George S.

Testu osoa Testu osoa Testu osoa

Colorectal Adenomas Contain Multiple Somatic Mutations That Do Not Coincide with Synchronous Adenocarcinoma Specimens nork Vaqué, José P., Martínez, Nerea, Varela, Ignacio, Fernández, Fidel, Mayorga, Marta, Derdak, Sophia, Beltrán, Sergi, Moreno, Thaidy, Almaraz, Carmen, De las Heras, Gonzalo, Bayés, Mónica, Gut, Ivo, Crespo, Javier, Piris, Miguel A.

Testu osoa Testu osoa Testu osoa

Correction: Colorectal Adenomas Contain Multiple Somatic Mutations That Do Not Coincide with Synchronous Adenocarcinoma Specimens nork Vaqué, José P., Martínez, Nerea, Varela, Ignacio, Fernández, Fidel, Mayorga, Marta, Derdak, Sophia, Beltrán, Sergi, Moreno, Thaidy, Almaraz, Carmen, De las Heras, Gonzalo, Bayés, Mónica, Gut, Ivo, Crespo, Javier, Piris, Miguel A.

Testu osoa Testu osoa Testu osoa

CD133-directed CAR T-cells for MLL leukemia: on-target, off-tumor myeloablative toxicity nork Bueno, Clara, Velasco-Hernandez, Talia, Gutiérrez-Agüera, Francisco, Zanetti, Samanta Romina, Baroni, Matteo L., Sánchez-Martínez, Diego, Molina, Oscar, Closa, Adria, Agraz-Doblás, Antonio, Marín, Pedro, Eyras, Eduardo, Varela, Ignacio, Menéndez, Pablo

Testu osoa Testu osoa Testu osoa

Bone Marrow Clonogenic Myeloid Progenitors from NPM1-Mutated AML Patients Do Not Harbor the NPM1 Mutation: Implication for the Cell-Of-Origin of NPM1+ AML nork Diaz de la Guardia, Rafael, González-Silva, Laura, López-Millán, Belén, Rodríguez-Sevilla, Juan José, Baroni, Matteo L., Bueno, Clara, Anguita, Eduardo, Vives, Susana, Palomo, Laura, Lapillonne, Helene, Varela, Ignacio, Menendez, Pablo

Testu osoa Testu osoa Testu osoa

Somatic structural rearrangements in genetically engineered mouse mammary tumors nork Varela, Ignacio, Klijn, Christiaan, Stephens, Phillip J, Mudie, Laura J, Stebbings, Lucy, Galappaththige, Danushka, van der Gulden, Hanneke, Schut, Eva, Klarenbeek, Sjoerd, Campbell, Peter J, Wessels, Lodewyk FA, Stratton, Michael R, Jonkers, Jos, Futreal, P Andrew, Adams, David J

Testu osoa Testu osoa Testu osoa

Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia nork Dovey, Oliver M., Cooper, Jonathan L., Mupo, Annalisa, Grove, Carolyn S., Lynn, Claire, Conte, Nathalie, Andrews, Robert M., Pacharne, Suruchi, Tzelepis, Konstantinos, Vijayabaskar, M. S., Green, Paul, Rad, Roland, Arends, Mark, Wright, Penny, Yusa, Kosuke, Bradley, Allan, Varela, Ignacio, Vassiliou, George S.

Testu osoa Testu osoa Testu osoa

The MNT transcription factor autoregulates its expression and supports proliferation in MYC-associated factor X (MAX)-deficient cells nork Lafita-Navarro, M. Carmen, Liaño-Pons, Judit, Quintanilla, Andrea, Varela, Ignacio, Blanco, Rosa, Ourique, Fabiana, Bretones, Gabriel, Aresti, Julia, Molina, Ester, Carroll, Patrick, Hurlin, Peter, Romero, Octavio A., Sanchez-Céspedes, Montse, Eisenman, Robert N., Delgado, M. Dolores, León, Javier

Testu osoa Testu osoa Testu osoa

Leukemia-Associated Somatic Mutations Drive Distinct Patterns of Age-Related Clonal Hemopoiesis nork McKerrell, Thomas, Park, Naomi, Moreno, Thaidy, Grove, Carolyn S., Ponstingl, Hannes, Stephens, Jonathan, Crawley, Charles, Craig, Jenny, Scott, Mike A., Hodkinson, Clare, Baxter, Joanna, Rad, Roland, Forsyth, Duncan R., Quail, Michael A., Zeggini, Eleftheria, Ouwehand, Willem, Varela, Ignacio, Vassiliou, George S.

Testu osoa Testu osoa Testu osoa

Characterization of gene mutations and copy number changes in acute myeloid leukemia using a rapid target enrichment protocol nork Bolli, Niccolò, Manes, Nicla, McKerrell, Thomas, Chi, Jianxiang, Park, Naomi, Gundem, Gunes, Quail, Michael A., Sathiaseelan, Vijitha, Herman, Bram, Crawley, Charles, Craig, Jenny I. O., Conte, Natalie, Grove, Carolyn, Papaemmanuil, Elli, Campbell, Peter J., Varela, Ignacio, Costeas, Paul, Vassiliou, George S.

Testu osoa Testu osoa Testu osoa

Analysis of the mutational landscape of classic Hodgkin lymphoma identifies disease heterogeneity and potential therapeutic targets nork Mata, Elena, Díaz-López, Antonio, Martín-Moreno, Ana M., Sánchez-Beato, Margarita, Varela, Ignacio, Mestre, María J., Santonja, Carlos, Burgos, Fernando, Menárguez, Javier, Estévez, Mónica, Provencio, Mariano, Sánchez-Espiridión, Beatriz, Díaz, Eva, Montalbán, Carlos, Piris, Miguel A., García, Juan F.

Testu osoa Testu osoa Testu osoa