Search Results - Valérie Domenga

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  1. 1
    Early white matter changes in CADASIL: evidence of segmental intramyelinic oedema in a pre-clinical mouse model

    Early white matter changes in CADASIL: evidence of segmental intramyelinic oedema in a pre-clinical mouse model by Emmanuel Cognat, Sabine Cléophax, Valérie Domenga‐Denier, Anne Joutel

    Published 2014
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  2. 2
    Pathogenic Mutations Associated with Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy Differently Affect Jagged1 Binding and Notch3 Activity via the RBP/JK Signaling Pathway

    Pathogenic Mutations Associated with Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy Differently Affect Jagged1 Binding and Notch3 Activi... by Anne Joutel, Marie Monet, Valérie Domenga, Florence Riant, Elisabeth Tournier‐Lasserve

    Published 2004
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  3. 3
    Impaired Cerebral Vasoreactivity in a Transgenic Mouse Model of Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy Arteriopathy

    Impaired Cerebral Vasoreactivity in a Transgenic Mouse Model of Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy Arteriopathy by Pierre Lacombe, Charleen Oligo, Valérie Domenga, Elisabeth Tournier‐Lasserve, Anne Joutel

    Published 2005
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  4. 4
    Increased Notch3 Activity Mediates Pathological Changes in Structure of Cerebral Arteries

    Increased Notch3 Activity Mediates Pathological Changes in Structure of Cerebral Arteries by Céline Baron‐Menguy, Valérie Domenga‐Denier, Lamia Ghezali, Frank M. Faraci, Anne Joutel

    Published 2016
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  5. 5
    Transgenic Mice Expressing Mutant Notch3 Develop Vascular Alterations Characteristic of Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy

    Transgenic Mice Expressing Mutant Notch3 Develop Vascular Alterations Characteristic of Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy by M M Ruchoux, Valérie Domenga, Peggy Brulin, Jacqueline Maciazek, Sylvie Limol, Elisabeth Tournier‐Lasserve, Anne Joutel

    Published 2003
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  6. 6
    Impaired Vascular Mechanotransduction in a Transgenic Mouse Model of CADASIL Arteriopathy

    Impaired Vascular Mechanotransduction in a Transgenic Mouse Model of CADASIL Arteriopathy by Caroline Dubroca, Pierre Lacombe, Valérie Domenga, Jacqueline Maciazek, Bernard Lévy, Elisabeth Tournier‐Lasserve, Anne Joutel, Daniel Henrion

    Published 2004
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  7. 7
    Blood brain barrier leakage is not a consistent feature of white matter lesions in CADASIL

    Blood brain barrier leakage is not a consistent feature of white matter lesions in CADASIL by Rikesh M. Rajani, Julien Ratelade, Valérie Domenga‐Denier, Yoshiki Hase, Hannu Kalimo, Raj N. Kalaria, Anne Joutel

    Published 2019
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  8. 8
    The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients

    The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients by Anne Joutel, F. Andreux, Swann Gaulis, Valérie Domenga, Michaelle Cécillon, Nicole Battail, Nadia Piga, Françoise Chapon, Catherine Godfrain, Elisabeth Tournier‐Lasserve

    Published 2000
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  9. 9
    The archetypal R90C CADASIL–NOTCH3 mutation retains NOTCH3 function in vivo

    The archetypal R90C CADASIL–NOTCH3 mutation retains NOTCH3 function in vivo by Marie Monet, Valérie Domenga, B. Lemaire, Céline Souilhol, Francina Langa, Charles Babinet, Thomas Gridley, Elisabeth Tournier‐Lasserve, Michel Cohen‐Tannoudji, Anne Joutel

    Published 2007
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  10. 10
    Reducing <scp>T</scp>imp3 or vitronectin ameliorates disease manifestations in <scp>CADASIL</scp> mice

    Reducing <scp>T</scp>imp3 or vitronectin ameliorates disease manifestations in <scp>CADASIL</scp> mice by Carmen Capone, Emmanuel Cognat, Lamia Ghezali, Céline Baron‐Menguy, Déborah Aubin, Laurent Mesnard, Heidi Stöhr, Valérie Domenga‐Denier, Mark T. Nelson, Anne Joutel

    Published 2015
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  11. 11
    Distinct phenotypic and functional features of CADASIL mutations in the Notch3 ligand binding domain

    Distinct phenotypic and functional features of CADASIL mutations in the Notch3 ligand binding domain by Marie Monet-Leprêtre, Boris Bardot, B. Lemaire, Valérie Domenga, O Godin, Martin Dichgans, Elisabeth Tournier‐Lasserve, Michel Cohen‐Tannoudji, Hugues Chabriat, Anne Joutel

    Published 2009
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  12. 12
    Abnormal recruitment of extracellular matrix proteins by excess Notch3ECD: a new pathomechanism in CADASIL

    Abnormal recruitment of extracellular matrix proteins by excess Notch3ECD: a new pathomechanism in CADASIL by Marie Monet-Leprêtre, Iman Haddad, Céline Baron‐Menguy, Maï Fouillot-Panchal, Meriem Riani, Valérie Domenga‐Denier, Claire Dussaule, Emmanuel Cognat, Joëlle Vinh, Anne Joutel

    Published 2013
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  13. 13
    Potassium channelopathy-like defect underlies early-stage cerebrovascular dysfunction in a genetic model of small vessel disease

    Potassium channelopathy-like defect underlies early-stage cerebrovascular dysfunction in a genetic model of small vessel disease by Fabrice Dabertrand, Christel Krøigaard, Adrian D. Bonev, Emmanuel Cognat, Thomas Dalsgaard, Valérie Domenga‐Denier, David C. Hill‐Eubanks, Joseph E. Brayden, Anne Joutel, Mark T. Nelson

    Published 2015
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  14. 14
    Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease

    Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease by Anne Joutel, Marie Monet-Leprêtre, Claudia Gösele, Céline Baron‐Menguy, Annette Hammes, Sabine Schmidt, Barbara Lemaire-Carrette, Valérie Domenga, Andreas Schedl, Pierre Lacombe, Norbert Hübner

    Published 2010
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  15. 15
    Mechanistic insights into a TIMP3-sensitive pathway constitutively engaged in the regulation of cerebral hemodynamics

    Mechanistic insights into a TIMP3-sensitive pathway constitutively engaged in the regulation of cerebral hemodynamics by Carmen Capone, Fabrice Dabertrand, Céline Baron‐Menguy, Athena Chalaris, Lamia Ghezali, Valérie Domenga‐Denier, Stefanie Schmidt, Clément Huneau, Stefan Rose‐John, Mark T. Nelson, Anne Joutel

    Published 2016
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  16. 16
    Protein aggregates containing wild-type and mutant NOTCH3 are major drivers of arterial pathology in CADASIL

    Protein aggregates containing wild-type and mutant NOTCH3 are major drivers of arterial pathology in CADASIL by Nicolas Dupré, Florian Gueniot, Valérie Domenga‐Denier, Virginie Dubosclard, Christelle Nilles, David C. Hill‐Eubanks, Christelle Morgenthaler-Roth, Mark T. Nelson, Céline Keime, Lydia Danglot, Anne Joutel

    Published 2024
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  17. 17
    <i>Notch3</i> is required for arterial identity and maturation of vascular smooth muscle cells

    <i>Notch3</i> is required for arterial identity and maturation of vascular smooth muscle cells by Valérie Domenga, Peggy Fardoux, Pierre Lacombe, Marie Monet, Jacqueline Maciazek, Luke T. Krebs, Bernard Klonjkowski, Eliane Berrou, Mathias Mericskay, Zhenlin Li, Elisabeth Tournier‐Lasserve, Thomas Gridley, Anne Joutel

    Published 2004
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  18. 18
    Notch3 Is a Major Regulator of Vascular Tone in Cerebral and Tail Resistance Arteries

    Notch3 Is a Major Regulator of Vascular Tone in Cerebral and Tail Resistance Arteries by Eric J. Belin de Chantemèle, Kevin Retailleau, Frédéric Pinaud, Emilie Vessières, Arnaud Bocquet, A.-L. Guihot, B. Lemaire, Valérie Domenga, Christophe Baufreton, Laurent Loufrani, Anne Joutel, Daniel Henrion

    Published 2008
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  19. 19
    Reducing Hypermuscularization of the Transitional Segment Between Arterioles and Capillaries Protects Against Spontaneous Intracerebral Hemorrhage

    Reducing Hypermuscularization of the Transitional Segment Between Arterioles and Capillaries Protects Against Spontaneous Intracerebral Hemorrhage by Julien Ratelade, Nicholas R. Klug, Damiano Lombardi, Monara Kaelle Servulo Cruz Angelim, Fabrice Dabertrand, Valérie Domenga‐Denier, Rustam Al‐Shahi Salman, Colin Smith, Jean-Frédéric Gerbeau, Mark T. Nelson, Anne Joutel

    Published 2020
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