Resultados de búsqueda - Utkarsh Tripathi

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  1. 1
    Impact of Senescent Cell Subtypes on Tissue Dysfunction and Repair: Importance and Research Questions

    Impact of Senescent Cell Subtypes on Tissue Dysfunction and Repair: Importance and Research Questions por Utkarsh Tripathi, Avanish Misra, Tamar Tchkonia, James L. Kirkland

    Publicado 2021
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  2. 2
    Targeting Cell Senescence and Senolytics: Novel Interventions for Age-Related Endocrine Dysfunction

    Targeting Cell Senescence and Senolytics: Novel Interventions for Age-Related Endocrine Dysfunction por Masayoshi Suda, Karl H. Paul, Utkarsh Tripathi, Tohru Minamino, Tamar Tchkonia, James L. Kirkland

    Publicado 2024
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  3. 3
    Cellular senescence in aging and age-related diseases: Implications for neurodegenerative diseases

    Cellular senescence in aging and age-related diseases: Implications for neurodegenerative diseases por Erin O. Wissler Gerdes, Yi Zhu, Bettina M. Weigand, Utkarsh Tripathi, Terence C. Burns, Tamar Tchkonia, James L. Kirkland

    Publicado 2020
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  4. 4
    Differential effect of amyloid beta peptides on mitochondrial axonal trafficking depends on their state of aggregation and binding to the plasma membrane

    Differential effect of amyloid beta peptides on mitochondrial axonal trafficking depends on their state of aggregation and binding to the plasma membrane por Liang Zhang, Sergey Trushin, Trace Christensen, Utkarsh Tripathi, Courtney C. Hong, Rachel E. Geroux, Kyle G. Howell, Joseph F. Poduslo, Eugenia Trushina

    Publicado 2018
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  5. 5
    Synaptic dysfunction and extracellular matrix dysregulation in dopaminergic neurons from sporadic and E326K-GBA1 Parkinson’s disease patients

    Synaptic dysfunction and extracellular matrix dysregulation in dopaminergic neurons from sporadic and E326K-GBA1 Parkinson’s disease patients por Idan Rosh, Utkarsh Tripathi, Yara Hussein, Wote Amelo Rike, Jose Djamus, Boris Shklyar, Andreea Manole, Henry Houlden, Jürgen Winkler, Fred H. Gage, Shani Stern

    Publicado 2024
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  6. 6
    Upregulated ECM genes and increased synaptic activity in Parkinson’s human DA neurons with PINK1/ PRKN mutations

    Upregulated ECM genes and increased synaptic activity in Parkinson’s human DA neurons with PINK1/ PRKN mutations por Utkarsh Tripathi, Idan Rosh, Ran Ben Ezer, Ritu Nayak, Yara Hussein, Ashwani Choudhary, Jose Djamus, Andreea Manole, Henry Houlden, Fred H. Gage, Shani Stern

    Publicado 2024
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  7. 7
    Early maturation and hyperexcitability is a shared phenotype of cortical neurons derived from different ASD-associated mutations

    Early maturation and hyperexcitability is a shared phenotype of cortical neurons derived from different ASD-associated mutations por Yara Hussein, Utkarsh Tripathi, Ashwani Choudhary, Ritu Nayak, David Peles, Idan Rosh, Tatiana Rabinski, Jose Djamus, Gad D. Vatine, Ronen Spiegel, Tali Garin-Shkolnik, Shani Stern

    Publicado 2023
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  8. 8
    SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3

    SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3 por Utkarsh Tripathi, Rayhane Nchioua, Larissa Prata, Yi Zhu, Erin O. Wissler Gerdes, Nino Giorgadze, Tamar Pirtskhalava, Erik Parker, Ailing Xue, Jair M. Espindola-Netto, Steffen Stenger, Paul D. Robbins, Laura J. Niedernhofer, Stephanie Dickinson, David B. Allison, Frank Kirchhoff, Konstantin M. J. Sparrer, Tamar Tchkonia, James L. Kirkland

    Publicado 2021
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  9. 9
    Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans

    Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans por Yi Zhu, Larissa Prata, Erin O. Wissler Gerdes, Jair Machado Espindola Netto, Tamar Pirtskhalava, Nino Giorgadze, Utkarsh Tripathi, Christina L. Inman, Kurt O. Johnson, Ailing Xue, Allyson K. Palmer, Tingjun Chen, Kalli K. Schaefer, Jamie N. Justice, Anoop M. Nambiar, Nicolas Musi, Stephen B. Kritchevsky, Jun Chen, Sundeep Khosla, Diana Jurk, Marissa J. Schafer, Tamar Tchkonia, James L. Kirkland

    Publicado 2022
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  10. 10
    Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission

    Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission por Shani Stern, Lei Zhang, Meiyan Wang, Rebecca A. Wright, Idan Rosh, Yara Hussein, Tchelet Stern, Ashwani Choudhary, Utkarsh Tripathi, Patrick Reed, Hagit Sadis, Ritu Nayak, Aviram Shemen, Karishma Agarwal, Diogo Cordeiro, David Peles, Yuqing Hang, Ana P. D. Mendes, Tithi D. Baul, Julien G. Roth, Shashank Coorapati, Marco P. Boks, W. Richard McCombie, Hilleke E. Hulshoff Pol, Kristen Brennand, János Réthelyi, René S. Kahn, Maria C. Marchetto, Fred H. Gage

    Publicado 2024
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  11. 11
    Partial inhibition of mitochondrial complex I ameliorates Alzheimer’s disease pathology and cognition in APP/PS1 female mice

    Partial inhibition of mitochondrial complex I ameliorates Alzheimer’s disease pathology and cognition in APP/PS1 female mice por Andrea Stojakovic, Sergey Trushin, Anthony Sheu, Layla Khalili, Su-Youne Chang, Xing Li, Trace Christensen, Jeffrey L. Salisbury, Rachel E. Geroux, Benjamin Gateno, Padraig J. Flannery, Mrunal Dehankar, Cory C. Funk, Jordan Wilkins, Анна Степанова, Tara O’Hagan, Alexander Galkin, Jarred J. Nesbitt, Xiujuan Zhu, Utkarsh Tripathi, Slobodan Macura, Tamar Tchkonia, Tamar Pirtskhalava, James L. Kirkland, Rachel A. Kudgus, Renee A. Schoon, Joel M. Reid, Yu Yamazaki, Takahisa Kanekiyo, Song Zhang, Emirhan Nemutlu, Petras P. Dzeja, Adam Jaspersen, Ye In Christopher Kwon, Michael K. Lee, Eugenia Trushina

    Publicado 2021
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  12. 12
    Senolytics reduce coronavirus-related mortality in old mice

    Senolytics reduce coronavirus-related mortality in old mice por Christina D. Camell, Matthew J. Yousefzadeh, Yi Zhu, Larissa Prata, Matthew A. Huggins, Mark Pierson, Lei Zhang, Ryan O’Kelly, Tamar Pirtskhalava, Pengcheng Xun, Keisuke Ejima, Ailing Xue, Utkarsh Tripathi, Jair M. Espindola-Netto, Nino Giorgadze, Elizabeth J. Atkinson, Christina L. Inman, Kurt O. Johnson, Stephanie H. Cholensky, Timothy W. Carlson, Nathan K. LeBrasseur, Sundeep Khosla, M. Gerard O’Sullivan, David B. Allison, Stephen C. Jameson, Alexander Meves, Ming Li, Y. S. Prakash, Sergio E. Chiarella, Sara E. Hamilton, Tamar Tchkonia, Laura J. Niedernhofer, James L. Kirkland, Paul D. Robbins

    Publicado 2021
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