Результаты поиска - Ungureanu, Daniela

Molecular Mechanisms Associated with ROR1-Mediated Drug Resistance: Crosstalk with Hippo-YAP/TAZ and BMI-1 Pathways по Karvonen, Hanna, Barker, Harlan, Kaleva, Laura, Niininen, Wilhelmiina, Ungureanu, Daniela

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Regulation of Jak2 through the Ubiquitin-Proteasome Pathway Involves Phosphorylation of Jak2 on Y1007 and Interaction with SOCS-1 по Ungureanu, Daniela, Saharinen, Pipsa, Junttila, Ilkka, Hilton, Douglas J., Silvennoinen, Olli

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Structure-function analysis indicates that sumoylation modulates DNA-binding activity of STAT1 по Grönholm, Juha, Vanhatupa, Sari, Ungureanu, Daniela, Väliaho, Jouni, Laitinen, Tuomo, Valjakka, Jarkko, Silvennoinen, Olli

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Analysis of Jak2 Catalytic Function by Peptide Microarrays: The Role of the JH2 Domain and V617F Mutation по Sanz, Arturo, Ungureanu, Daniela, Pekkala, Tuija, Ruijtenbeek, Rob, Touw, Ivo P., Hilhorst, Riet, Silvennoinen, Olli

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Crystal structures of the Jak2 pseudokinase domain and the pathogenic mutant V617F по Bandaranayake, Rajintha M., Ungureanu, Daniela, Shan, Yibing, Shaw, David E., Silvennoinen, Olli, Hubbard, Stevan R.

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ATP binding to the pseudokinase domain of JAK2 is critical for pathogenic activation по Hammarén, Henrik M., Ungureanu, Daniela, Grisouard, Jean, Skoda, Radek C., Hubbard, Stevan R., Silvennoinen, Olli

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Evaluating Targeted Therapies in Ovarian Cancer Metabolism: Novel Role for PCSK9 and Second Generation mTOR Inhibitors по Jacome Sanz, Dafne, Raivola, Juuli, Karvonen, Hanna, Arjama, Mariliina, Barker, Harlan, Murumägi, Astrid, Ungureanu, Daniela

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New insights into the molecular mechanisms of ROR1, ROR2, and PTK7 signaling from the proteomics and pharmacological modulation of ROR1 interactome по Raivola, Juuli, Dini, Alice, Salokas, Kari, Karvonen, Hanna, Niininen, Wilhelmiina, Piki, Emilia, Varjosalo, Markku, Ungureanu, Daniela

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STRN-ALK rearranged pediatric malignant peritoneal mesothelioma – Functional testing of 527 cancer drugs in patient-derived cancer cells по Murumägi, Astrid, Ungureanu, Daniela, Arjama, Mariliina, Bützow, Ralf, Lohi, Jouko, Sariola, Hannu, Kanerva, Jukka, Koskenvuo, Minna, Kallioniemi, Olli

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Identification and Characterization of JAK2 Pseudokinase Domain Small Molecule Binders по Puleo, David E., Kucera, Kaury, Hammarén, Henrik M., Ungureanu, Daniela, Newton, Ana S., Silvennoinen, Olli, Jorgensen, William L., Schlessinger, Joseph

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The impact of donor liver graft quality on postoperative outcome in liver transplant recipients. A single centre experience по Tomescu, Dana, Popescu, Mihai, Jipa, Lavinia, Fota, Ruxandra, Ungureanu, Daniela, Zamfir, Radu, Orban, Carmen, Dima, Simona Olimpia, Popescu, Irinel

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Molecular basis for pseudokinase-dependent autoinhibition of JAK2 tyrosine kinase по Shan, Yibing, Gnanasambandan, Kavitha, Ungureanu, Daniela, Kim, Eric T., Hammarén, Henrik, Yamashita, Kazuo, Silvennoinen, Olli, Shaw, David E., Hubbard Shaw, Stevan R.

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High-throughput ex vivo drug testing identifies potential drugs and drug combinations for NRAS-positive malignant melanoma по Kohtamäki, Laura, Arjama, Mariliina, Mäkelä, Siru, Ianevski, Philipp, Välimäki, Katja, Juteau, Susanna, Ilmonen, Suvi, Ungureanu, Daniela, Kallioniemi, Olli, Murumägi, Astrid, Hernberg, Micaela

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Crosstalk between ROR1 and BCR pathways defines novel treatment strategies in mantle cell lymphoma по Karvonen, Hanna, Chiron, David, Niininen, Wilhelmiina, Ek, Sara, Jerkeman, Mats, Moradi, Elaheh, Nykter, Matti, Heckman, Caroline A., Kallioniemi, Olli, Murumägi, Astrid, Ungureanu, Daniela

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The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling по Ungureanu, Daniela, Wu, Jinhua, Pekkala, Tuija, Niranjan, Yashavanthi, Young, Clifford, Jensen, Ole N., Xu, Chong-Feng, Neubert, Thomas A., Skoda, Radek C., Hubbard, Stevan R., Silvennoinen, Olli

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Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analyses по Varghese, Leila N., Ungureanu, Daniela, Liau, Nicholas P. D., Young, Samuel N., Laktyushin, Artem, Hammaren, Henrik, Lucet, Isabelle S., Nicola, Nicos A., Silvennoinen, Olli, Babon, Jeffrey J., Murphy, James M.

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Glucocorticoids induce differentiation and chemoresistance in ovarian cancer by promoting ROR1-mediated stemness по Karvonen, Hanna, Arjama, Mariliina, Kaleva, Laura, Niininen, Wilhelmiina, Barker, Harlan, Koivisto-Korander, Riitta, Tapper, Johanna, Pakarinen, Päivi, Lassus, Heini, Loukovaara, Mikko, Bützow, Ralf, Kallioniemi, Olli, Murumägi, Astrid, Ungureanu, Daniela

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Structural insights into pseudokinase domains of receptor tyrosine kinases по Sheetz, Joshua B., Mathea, Sebastian, Karvonen, Hanna, Malhotra, Ketan, Chatterjee, Deep, Niininen, Wilhelmiina, Perttilä, Robert, Preuss, Franziska, Suresh, Krishna, Stayrook, Steven E., Tsutsui, Yuko, Radhakrishnan, Ravi, Ungureanu, Daniela, Knapp, Stefan, Lemmon, Mark A.

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Perioperative Patient Blood Management Programme. Multidisciplinary recommendations from the Patient Blood Management Initiative Group по Filipescu, Daniela, Bănăţeanu, Răzvan, Beuran, Mircea, Burcoş, Traean, Corneci, Dan, Cristian, Dan, Diculescu, Mircea, Dobrotă, Alina, Droc, Gabriela, Isacoff, Dănuţ, Goşa, Doina, Grinţescu, Ioana, Lupu, Anca, Mirea, Liliana, Posea, Corina, Stanca, Oana, Ştefan, Mihai, Tomescu, Dana, Tudor, Cristina, Ungureanu, Daniela, Mircescu, Gabriel

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A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties по Murphy, James M., Zhang, Qingwei, Young, Samuel N., Reese, Michael L., Bailey, Fiona P., Eyers, Patrick A., Ungureanu, Daniela, Hammaren, Henrik, Silvennoinen, Olli, Varghese, Leila N., Chen, Kelan, Tripaydonis, Anne, Jura, Natalia, Fukuda, Koichi, Qin, Jun, Nimchuk, Zachary, Mudgett, Mary Beth, Elowe, Sabine, Gee, Christine L., Liu, Ling, Daly, Roger J., Manning, Gerard, Babon, Jeffrey J., Lucet, Isabelle S.

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