検索結果 - Ulrich Lücking
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BAY 1000394, a Novel Cyclin-Dependent Kinase Inhibitor, with Potent Antitumor Activity in Mono- and in Combination Treatment upon Oral Application 著者: Gerhard Siemeister, Ulrich Lücking, Antje M. Wengner, Philip Lienau, Wolfram Steinke, Christoph A. Schatz, Dominik Mumberg, Karl Ziegelbauer
出版事項 2012Artigo -
2
Conformational Adaption May Explain the Slow Dissociation Kinetics of Roniciclib (BAY 1000394), a Type I CDK Inhibitor with Kinetic Selectivity for CDK2 and CDK9 著者: Pelin Ayaz, Dorothee Andres, Dennis Kwiatkowski, Carl‐Christian Kolbe, Philip Lienau, Gerhard Siemeister, Ulrich Lücking, Christian M. Stegmann
出版事項 2016Artigo -
3
The Novel ATR Inhibitor BAY 1895344 Is Efficacious as Monotherapy and Combined with DNA Damage–Inducing or Repair–Compromising Therapies in Preclinical Cancer Models 著者: Antje M. Wengner, Gerhard Siemeister, Ulrich Lücking, Julien Lefranc, Lars Wortmann, Philip Lienau, Benjamin Bader, Ulf Bömer, Dieter Moosmayer, Uwe Eberspächer, Sven Golfier, Christoph A. Schatz, Simon J. Baumgart, Bernard Haendler, Pascale Lejeune, Andreas Schlicker, Franz von Nussbaum, Michael Brands, Karl Ziegelbauer, Dominik Mumberg
出版事項 2019Artigo -
4
Identification of Atuveciclib (BAY 1143572), the First Highly Selective, Clinical PTEFb/CDK9 Inhibitor for the Treatment of Cancer 著者: Ulrich Lücking, Arne Scholz, Philip Lienau, Gerhard Siemeister, Dirk Kosemund, Rolf Bohlmann, Hans Briem, Ildiko Terebesi, Kirstin Meyer, Katja Prelle, Karsten Denner, Ulf Bömer, Martina Schäfer, Knut Eis, Ray Valencia, Stuart Ince, Franz von Nussbaum, Dominik Mumberg, Karl Ziegelbauer, Bert Klebl, Axel Choidas, Peter Nußbaumer, Matthias Baumann, Carsten Schultz‐Fademrecht, Gerd Rühter, Jan Eickhoff, Michael Brands
出版事項 2017Artigo
関連主題
Biochemistry
Biology
Chemistry
Kinase
Pharmacology
Cancer research
Cell cycle
Cyclin-dependent kinase
Cyclin-dependent kinase 2
Medicine
Protein kinase A
Adverse effect
Apoptosis
Bay
CDK inhibitor
Cancer
Cancer cell
Carcinogenesis
Cell
Cell growth
Civil engineering
Cyclin-dependent kinase 1
Cyclin-dependent kinase 6
DNA
DNA damage
DNA repair
Engineering
Genetics
In vivo
Internal medicine