Torthaí cuardaigh - Tree, Timothy

Reconstruction of a pathway of antigen processing and class II MHC peptide capture de réir Moss, Catherine X, Tree, Timothy I, Watts, Colin

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

Regulatory T cell dysfunction in type 1 diabetes: what’s broken and how can we fix it? de réir Hull, Caroline M., Peakman, Mark, Tree, Timothy I. M.

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

HLA Class II molecules on haplotypes associated with type 1 diabetes exhibit similar patterns of binding affinities for coxsackievirus P2C peptides de réir Ellis, Richard J, Varela-Calvino, Ruben, Tree, Timothy I M, Peakman, Mark

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

Naturally Arising Human CD4 T-Cells That Recognize Islet Autoantigens and Secrete Interleukin-10 Regulate Proinflammatory T-Cell Responses via Linked Suppression de réir Tree, Timothy I.M., Lawson, Jennifer, Edwards, Hannah, Skowera, Ania, Arif, Sefina, Roep, Bart O., Peakman, Mark

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health de réir Arif, Sefina, Tree, Timothy I., Astill, Thomas P., Tremble, Jennifer M., Bishop, Amanda J., Dayan, Colin M., Roep, Bart O., Peakman, Mark

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

The Expression of Active CD11b Monocytes in Blood and Disease Progression in Amyotrophic Lateral Sclerosis de réir Yildiz, Ozlem, Schroth, Johannes, Lombardi, Vittoria, Pucino, Valentina, Bobeva, Yoana, Yip, Ping Kei, Schmierer, Klaus, Mauro, Claudio, Tree, Timothy, Henson, Sian Mari, Malaspina, Andrea

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

Standardizing T-Cell Biomarkers in Type 1 Diabetes: Challenges and Recent Advances de réir Ahmed, Simi, Cerosaletti, Karen, James, Eddie, Long, S. Alice, Mannering, Stuart, Speake, Cate, Nakayama, Maki, Tree, Timothy, Roep, Bart O., Herold, Kevan C., Brusko, Todd M.

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

INNODIA Master Protocol for the evaluation of investigational medicinal products in children, adolescents and adults with newly diagnosed type 1 diabetes de réir Dunger, David B., Bruggraber, Sylvaine F. A., Mander, Adrian P., Marcovecchio, M. Loredana, Tree, Timothy, Chmura, Piotr Jaroslaw, Knip, Mikael, Schulte, Anke M., Mathieu, Chantal

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

Multipotent Adult Progenitor Cells Suppress T Cell Activation in In Vivo Models of Homeostatic Proliferation in a Prostaglandin E2-Dependent Manner de réir Carty, Fiona, Corbett, Jennifer M., Cunha, João Paulo M. C. M., Reading, James L., Tree, Timothy I. M., Ting, Anthony E., Stubblefield, Samantha R., English, Karen

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

Mapping T Cell Responses to Native and Neo-Islet Antigen Epitopes in at Risk and Type 1 Diabetes Subjects de réir Arif, Sefina, Pujol-Autonell, Irma, Kamra, Yogesh, Williams, Evangelia, Yusuf, Norkhairin, Domingo-Vila, Clara, Shahrabi, Yasaman, Pollock, Emily, Khatri, Leena, Peakman, Mark, Tree, Timothy, Lorenc, Anna

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

Plasmacytoid Dendritic Cells Are Proportionally Expanded at Diagnosis of Type 1 Diabetes and Enhance Islet Autoantigen Presentation to T-Cells Through Immune Complex Capture de réir Allen, Jennifer S., Pang, Karl, Skowera, Ania, Ellis, Richard, Rackham, Chloe, Lozanoska-Ochser, Biliana, Tree, Timothy, Leslie, R. David G., Tremble, Jennifer M., Dayan, Colin M., Peakman, Mark

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

GAD-alum immunotherapy in type 1 diabetes expands bifunctional Th1/Th2 autoreactive CD4 T cells de réir Arif, Sefina, Gomez-Tourino, Iria, Kamra, Yogesh, Pujol-Autonell, Irma, Hanton, Emily, Tree, Timothy, Melandri, Daisy, Hull, Caroline, Wherrett, Diane K., Beam, Craig, Roep, Bart O., Lorenc, Anna, Peakman, Mark

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

Type 1 Diabetes-associated IL2RAvariationlowers IL-2 signaling and contributes to diminished CD4(+)CD25(+) regulatory T-cell function de réir Garg, Garima, Tyler, Jennifer R, Yang, Jennie H M, Cutler, Antony J, Downes, Kate, Pekalski, Marcin, Bell, Louise, Nutland, Sarah, Peakman, Mark, Todd, John A, Wicker, Linda S, Tree, Timothy I M

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

Immune and Metabolic Effects of Antigen-Specific Immunotherapy Using Multiple β-Cell Peptides in Type 1 Diabetes de réir Liu, Yuk-Fun, Powrie, Jake, Arif, Sefina, Yang, Jennie H.M., Williams, Evangelia, Khatri, Leena, Joshi, Mamta, Lhuillier, Loic, Fountoulakis, Nikolaos, Smith, Emma, Beam, Craig, Lorenc, Anna, Peakman, Mark, Tree, Timothy

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

Systemic inflammatory response and neuromuscular involvement in amyotrophic lateral sclerosis de réir Lu, Ching-Hua, Allen, Kezia, Oei, Felicia, Leoni, Emanuela, Kuhle, Jens, Tree, Timothy, Fratta, Pietro, Sharma, Nikhil, Sidle, Katie, Howard, Robin, Orrell, Richard, Fish, Mark, Greensmith, Linda, Pearce, Neil, Gallo, Valentina, Malaspina, Andrea

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

Augmented Expansion of Treg Cells From Healthy and Autoimmune Subjects via Adult Progenitor Cell Co-Culture de réir Reading, James L., Roobrouck, Valerie D., Hull, Caroline M., Becker, Pablo Daniel, Beyens, Jelle, Valentin-Torres, Alice, Boardman, Dominic, Lamperti, Estefania Nova, Stubblefield, Samantha, Lombardi, Giovanna, Deans, Robert, Ting, Anthony E., Tree, Timothy

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated β-Cell Death de réir Arif, Sefina, Moore, Fabrice, Marks, Katherine, Bouckenooghe, Thomas, Dayan, Colin M., Planas, Raquel, Vives-Pi, Marta, Powrie, Jake, Tree, Timothy, Marchetti, Piero, Huang, Guo Cai, Gurzov, Esteban N., Pujol-Borrell, Ricardo, Eizirik, Decio L., Peakman, Mark

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

IL-2 therapy restores regulatory T-cell dysfunction induced by calcineurin inhibitors de réir Whitehouse, Gavin, Gray, Elizabeth, Mastoridis, Sotiris, Merritt, Elliot, Kodela, Elisavet, Yang, Jennie H. M., Danger, Richard, Mairal, Marta, Christakoudi, Sofia, Lozano, Juan J., Macdougall, Iain C., Tree, Timothy I. M., Sanchez-Fueyo, Alberto, Martinez-Llordella, Marc

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

Suppression of IL-7-dependent Effector T-cell Expansion by Multipotent Adult Progenitor Cells and PGE2 de réir Reading, James L, Vaes, Bart, Hull, Caroline, Sabbah, Shereen, Hayday, Thomas, Wang, Nancy S, DiPiero, Anthony, Lehman, Nicholas A, Taggart, Jen M, Carty, Fiona, English, Karen, Pinxteren, Jef, Deans, Robert, Ting, Anthony E, Tree, Timothy I M

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán

Natural variation in IL-2 sensitivity influences regulatory T cell frequency and function in individuals with long-standing type 1 diabetes de réir Yang, Jennie H.M., Cutler, Antony J., Ferreira, Ricardo C., Reading, James L., Cooper, Nicholas J., Wallace, Chris, Clarke, Pamela, Smyth, Deborah J., Boyce, Christopher S., Gao, Guo-Jian, Todd, John A., Wicker, Linda S., Tree, Timothy I.M.

Faigh an téacs iomlán Faigh an téacs iomlán Faigh an téacs iomlán