Search Results - Townsend, Michael J

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  1. 1
    Promising bone-related targets for rheumatoid arthritis therapy

    Promising bone-related targets for rheumatoid arthritis therapy by Choi, Yongwon, Arron, Joseph R., Townsend, Michael J.

    Published 2009
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  2. 2
    Levels of CXCL13 and sICAM-1 correlate with disease activity score in patients with rheumatoid arthritis treated with tocilizumab

    Levels of CXCL13 and sICAM-1 correlate with disease activity score in patients with rheumatoid arthritis treated with tocilizumab by Tuckwell, Katie, Gabay, Cem, Sornasse, Thierry, Laubender, Ruediger Paul, Wang, Jianmei, Townsend, Michael J.

    Published 2019
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  3. 3
    The Absence of Interleukin 9 Does Not Affect the Development of Allergen-induced Pulmonary Inflammation nor Airway Hyperreactivity

    The Absence of Interleukin 9 Does Not Affect the Development of Allergen-induced Pulmonary Inflammation nor Airway Hyperreactivity by McMillan, Sarah J., Bishop, Benjamin, Townsend, Michael J., McKenzie, Andrew N., Lloyd, Clare M.

    Published 2002
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  4. 4
    T1/St2-Deficient Mice Demonstrate the Importance of T1/St2 in Developing Primary T Helper Cell Type 2 Responses

    T1/St2-Deficient Mice Demonstrate the Importance of T1/St2 in Developing Primary T Helper Cell Type 2 Responses by Townsend, Michael J., Fallon, Padraic G., Matthews, David J., Jolin, Helen E., McKenzie, Andrew N.J.

    Published 2000
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  5. 5
    MTRX1011A, a humanized anti-CD4 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: a Phase I randomized, double-blind, placebo-controlled study incorporating pharmacodynamic biomarker assessments

    MTRX1011A, a humanized anti-CD4 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: a Phase I randomized, double-blind, placebo-controlled study incorporat... by Scheerens, Heleen, Su, Zheng, Irving, Bryan, Townsend, Michael J, Zheng, Yanan, Stefanich, Eric, Chindalore, Vishala, Bingham, Clifton O, Davis, John C

    Published 2011
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  6. 6
    The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes

    The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes by Jenner, Richard G., Townsend, Michael J., Jackson, Ian, Sun, Kaiming, Bouwman, Russell D., Young, Richard A., Glimcher, Laurie H., Lord, Graham M.

    Published 2009
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  7. 7
    Antibodies against human endogenous retrovirus K102 envelope activate neutrophils in systemic lupus erythematosus

    Antibodies against human endogenous retrovirus K102 envelope activate neutrophils in systemic lupus erythematosus by Tokuyama, Maria, Gunn, Bronwyn M., Venkataraman, Arvind, Kong, Yong, Kang, Insoo, Rakib, Tasfia, Townsend, Michael J., Costenbader, Karen H., Alter, Galit, Iwasaki, Akiko

    Published 2021
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  8. 8
    Efficacy and safety of pateclizumab (anti-lymphotoxin-α) compared to adalimumab in rheumatoid arthritis: a head-to-head phase 2 randomized controlled study (The ALTARA Study)

    Efficacy and safety of pateclizumab (anti-lymphotoxin-α) compared to adalimumab in rheumatoid arthritis: a head-to-head phase 2 randomized controlled study (The ALTARA Study) by Kennedy, William P, Simon, J Abraham, Offutt, Carolyn, Horn, Priscilla, Herman, Ann, Townsend, Michael J, Tang, Meina T, Grogan, Jane L, Hsieh, Frank, Davis, John C

    Published 2014
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  9. 9
    SIGN-R1 Contributes to Protection against Lethal Pneumococcal Infection in Mice

    SIGN-R1 Contributes to Protection against Lethal Pneumococcal Infection in Mice by Lanoue, Astrid, Clatworthy, Menna R., Smith, Philippa, Green, Sheila, Townsend, Michael J., Jolin, Helen E., Smith, Kenneth G.C., Fallon, Padraic G., McKenzie, Andrew N.J.

    Published 2004
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  10. 10
    Distal Regions of the Human IFNG Locus Direct Cell Type-Specific Expression

    Distal Regions of the Human IFNG Locus Direct Cell Type-Specific Expression by Collins, Patrick L., Chang, Shaojing, Henderson, Melodie, Soutto, Mohammed, Davis, Georgia M., McLoed, Allyson G., Townsend, Michael J., Glimcher, Laurie H., Mortlock, Douglas P., Aune, Thomas M.

    Published 2010
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  11. 11
    Association of Endogenous Anti–Interferon-α Autoantibodies With Decreased Interferon-Pathway and Disease Activity in Patients With Systemic Lupus Erythematosus

    Association of Endogenous Anti–Interferon-α Autoantibodies With Decreased Interferon-Pathway and Disease Activity in Patients With Systemic Lupus Erythematosus by Morimoto, Alyssa M., Flesher, Donna Thibault, Yang, Jihong, Wolslegel, Kristen, Wang, Xiangdan, Brady, Ann, Abbas, Alexander R., Quarmby, Valerie, Wakshull, Eric, Richardson, Bruce, Townsend, Michael J., Behrens, Timothy W.

    Published 2011
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  12. 12
    Association of the interferon signature metric with serological disease manifestations but not global activity scores in multiple cohorts of patients with SLE

    Association of the interferon signature metric with serological disease manifestations but not global activity scores in multiple cohorts of patients with SLE by Kennedy, William P, Maciuca, Romeo, Wolslegel, Kristen, Tew, Wei, Abbas, Alexander R, Chaivorapol, Christina, Morimoto, Alyssa, McBride, Jacqueline M, Brunetta, Paul, Richardson, Bruce C, Davis, John C, Behrens, Timothy W, Townsend, Michael J

    Published 2015
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  13. 13
    Anti-Vimentin Antibodies: A Unique Antibody Class Associated with Therapy-Resistant Lupus Nephritis

    Anti-Vimentin Antibodies: A Unique Antibody Class Associated with Therapy-Resistant Lupus Nephritis by Kinloch, Andrew J., Cascino, Matthew D., Dai, Jian, Bermea, Rene S, Ko, Kichul, Vesselits, Margaret, Dragone, Leonard L, Vaknin, Nirit Mor, Legendre, Maureen, Markovitz, David M, Okoreeh, Michael K, Townsend, Michael J., Clark, Marcus R.

    Published 2020
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  14. 14
    Influence of genetic copy number variants of the human GLUT3 glucose transporter gene SLC2A3 on protein expression, glycolysis and rheumatoid arthritis risk: A genetic replication study

    Influence of genetic copy number variants of the human GLUT3 glucose transporter gene SLC2A3 on protein expression, glycolysis and rheumatoid arthritis risk: A genetic replication... by Simpfendorfer, Kim R., Li, Wentian, Shih, Andrew, Wen, Hongxiu, Kothari, Harini P., Einsidler, Edward A., Wuster, Arthur, Hunkapiller, Julie, Behrens, Timothy W., Graham, Robert R., Townsend, Michael J., Behar, Doron M., Hu, Rui, Greenspan, Elliott, Gregersen, Peter K.

    Published 2019
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  15. 15
    Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent biological therapy: results from the pathobiology of early arthritis cohort (PEAC)

    Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent biolo... by Lliso-Ribera, Gloria, Humby, Frances, Lewis, Myles, Nerviani, Alessandra, Mauro, Daniele, Rivellese, Felice, Kelly, Stephen, Hands, Rebecca, Bene, Fabiola, Ramamoorthi, Nandhini, Hackney, Jason A, Cauli, Alberto, Choy, Ernest H, Filer, Andrew, Taylor, Peter C, McInnes, Iain, Townsend, Michael J, Pitzalis, Costantino

    Published 2019
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  16. 16
    Synovial phenotypes in rheumatoid arthritis correlate with response to biologic therapeutics

    Synovial phenotypes in rheumatoid arthritis correlate with response to biologic therapeutics by Dennis, Glynn, Holweg, Cécile TJ, Kummerfeld, Sarah K, Choy, David F, Setiadi, A Francesca, Hackney, Jason A, Haverty, Peter M, Gilbert, Houston, Lin, Wei Yu, Diehl, Lauri, Fischer, S, Song, An, Musselman, David, Klearman, Micki, Gabay, Cem, Kavanaugh, Arthur, Endres, Judith, Fox, David A, Martin, Flavius, Townsend, Michael J

    Published 2014
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  17. 17
    Activation of naïve CD4(+) T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4(+) T cells

    Activation of naïve CD4(+) T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4(+) T cells by Twohig, Jason P., Figueras, Ana Cardus, Andrews, Robert, Wiede, Florian, Cossins, Benjamin C., Soria, Alicia Derrac, Lewis, Myles J., Townsend, Michael J., Millrine, David, Li, Jasmine, Hill, David G., Fernandez, Javier Uceda, Liu, Xiao, Szomolay, Barbara, Pepper, Christopher J., Taylor, Philip R., Pitzalis, Costantino, Tiganis, Tony, Williams, Nigel M., Jones, Gareth W., Jones, Simon A.

    Published 2019
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  18. 18
    Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients

    Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients by Humby, Frances, Lewis, Myles, Ramamoorthi, Nandhini, Hackney, Jason A, Barnes, Michael R, Bombardieri, Michele, Setiadi, A. Francesca, Kelly, Stephen, Bene, Fabiola, DiCicco, Maria, Riahi, Sudeh, Rocher, Vidalba, Ng, Nora, Lazarou, Ilias, Hands, Rebecca, van der Heijde, Désirée, Landewé, Robert B M, van der Helm-van Mil, Annette, Cauli, Alberto, McInnes, Iain, Buckley, Christopher Dominic, Choy, Ernest H, Taylor, Peter C, Townsend, Michael J, Pitzalis, Costantino

    Published 2019
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  19. 19
    Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell–associated damage in IFNα-driven lupus nephritis

    Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell–associated damage in IFNα-driven lupus nephritis by Katewa, Arna, Wang, Yugang, Hackney, Jason A., Huang, Tao, Suto, Eric, Ramamoorthi, Nandhini, Austin, Cary D., Bremer, Meire, Chen, Jacob Zhi, Crawford, James J., Currie, Kevin S., Blomgren, Peter, DeVoss, Jason, DiPaolo, Julie A., Hau, Jonathan, Johnson, Adam, Lesch, Justin, DeForge, Laura E., Lin, Zhonghua, Liimatta, Marya, Lubach, Joseph W., McVay, Sami, Modrusan, Zora, Nguyen, Allen, Poon, Chungkee, Wang, Jianyong, Liu, Lichuan, Lee, Wyne P., Wong, Harvey, Young, Wendy B., Townsend, Michael J., Reif, Karin

    Published 2017
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  20. 20
    Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes

    Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes by Lewis, Myles J., Barnes, Michael R., Blighe, Kevin, Goldmann, Katriona, Rana, Sharmila, Hackney, Jason A., Ramamoorthi, Nandhini, John, Christopher R., Watson, David S., Kummerfeld, Sarah K., Hands, Rebecca, Riahi, Sudeh, Rocher-Ros, Vidalba, Rivellese, Felice, Humby, Frances, Kelly, Stephen, Bombardieri, Michele, Ng, Nora, DiCicco, Maria, van der Heijde, Désirée, Landewé, Robert, van der Helm-van Mil, Annette, Cauli, Alberto, McInnes, Iain B., Buckley, Christopher D., Choy, Ernest, Taylor, Peter C., Townsend, Michael J., Pitzalis, Costantino

    Published 2019
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