Rezultati - Torben Schiffner

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  1. 1
    Development of prophylactic vaccines against HIV-1

    Development of prophylactic vaccines against HIV-1 od Torben Schiffner, Quentin J. Sattentau, Lucy Dorrell

    Izdano 2013
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  2. 2
    Combining machine learning with structure-based protein design to predict and engineer post-translational modifications of proteins

    Combining machine learning with structure-based protein design to predict and engineer post-translational modifications of proteins od Moritz Ertelt, Vikram Khipple Mulligan, Jack B. Maguire, Sergey Lyskov, Rocco Moretti, Torben Schiffner, Jens Meiler, Clara T. Schoeder

    Izdano 2024
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  3. 3
    High-Multiplicity HIV-1 Infection and Neutralizing Antibody Evasion Mediated by the Macrophage-T Cell Virological Synapse

    High-Multiplicity HIV-1 Infection and Neutralizing Antibody Evasion Mediated by the Macrophage-T Cell Virological Synapse od C.J. Duncan, James P. Williams, Torben Schiffner, Kathleen Gärtner, Christina Ochsenbauer, John C. Kappes, Rebecca A. Russell, John Frater, Quentin J. Sattentau

    Izdano 2013
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  4. 4
    DNA origami vaccines program antigen-focused germinal centers

    DNA origami vaccines program antigen-focused germinal centers od Anna Romanov, Grant A. Knappe, Larance Ronsard, Heikyung Suh, Marjan Omer, Asheley P. Chapman, Vanessa Lewis, Katie Spivakovsky, Janet Ofelia Guevara Canales, Boris Reizis, Ryan Tingle, Christopher A. Cottrell, Torben Schiffner, Daniel Lingwood, Mark Bathe, Darrell J. Irvine

    Izdano 2025
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  5. 5
    Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design

    Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design od A. Irimia, Andreia M. Serra, Anita Sarkar, Ronald Jacak, Oleksandr Kalyuzhniy, Devin Sok, Karen L. Saye-Francisco, Torben Schiffner, Ryan Tingle, Michael Kubitz, Yumiko Adachi, Robyn L. Stanfield, Marc C. Deller, Dennis R. Burton, William R. Schief, Ian A. Wilson

    Izdano 2017
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  6. 6
    Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells

    Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells od Deli Huang, Jenny Tuyet Tran, Alex Olson, Thomas Vollbrecht, Mary Tenuta, Mariia V. Guryleva, Roberta Fuller, Torben Schiffner, Justin R. Abadejos, Lauren Couvrette, Tanya R. Blane, Karen Saye, Wenjuan Li, Elise Landais, Alicia González-Martín, William R. Schief, Ben Murrell, Dennis R. Burton, David Nemazee, James E. Voss

    Izdano 2020
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  7. 7
    Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding

    Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding od Daniel W. Kulp, Jon M. Steichen, Matthias Pauthner, Xiaozhen Hu, Torben Schiffner, Alessia Liguori, Christopher A. Cottrell, Colin Havenar‐Daughton, Gabriel Ozorowski, Erik Georgeson, Oleksandr Kalyuzhniy, Jordan R. Willis, Michael Kubitz, Yumiko Adachi, Samantha Reiss, Mia Shin, Natalia de Val, Andrew B. Ward, Shane Crotty, Dennis R. Burton, William R. Schief

    Izdano 2017
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  8. 8
    Rapid and Focused Maturation of a VRC01-Class HIV Broadly Neutralizing Antibody Lineage Involves Both Binding and Accommodation of the N276-Glycan

    Rapid and Focused Maturation of a VRC01-Class HIV Broadly Neutralizing Antibody Lineage Involves Both Binding and Accommodation of the N276-Glycan od Jeffrey C. Umotoy, Bernard S. Bagaya, Collin Joyce, Torben Schiffner, Sergey Menis, Karen L. Saye-Francisco, Trevor Biddle, Sanjay Mohan, Thomas Vollbrecht, Oleksandr Kalyuzhniy, Sharon Madzorera, Dale Kitchin, Bronwen E. Lambson, Molati Nonyane, William Kilembe, Pascal Poignard, William R. Schief, Dennis R. Burton, Ben Murrell, Penny L. Moore, Bryan Briney, Devin Sok, Elise Landais

    Izdano 2019
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  9. 9
    The human naive B cell repertoire contains distinct subclasses for a germline-targeting HIV-1 vaccine immunogen

    The human naive B cell repertoire contains distinct subclasses for a germline-targeting HIV-1 vaccine immunogen od Colin Havenar‐Daughton, Anita Sarkar, Daniel W. Kulp, Laura Toy, Xiaozhen Hu, Isaiah Deresa, Oleksandr Kalyuzhniy, Kirti Kaushik, Amit A. Upadhyay, Sergey Menis, Elise Landais, Liwei Cao, Jolene K. Diedrich, Sonu Kumar, Torben Schiffner, Samantha Reiss, Grégory Seumois, John R. Yates, James C. Paulson, Steven E. Bosinger, Ian A. Wilson, William R. Schief, Shane Crotty

    Izdano 2018
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  10. 10
    Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations

    Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations od Jacob T. Martin, Christopher A. Cottrell, Aleksandar Antanasijevic, Diane G. Carnathan, Benjamin J. Cossette, Chiamaka A. Enemuo, Etse H. Gebru, Yury Choe, Federico Viviano, Stephanie Fischinger, Talar Tokatlian, Kimberly M. Cirelli, George Ueda, Jeffrey Copps, Torben Schiffner, Sergey Menis, Galit Alter, William R. Schief, Shane Crotty, Neil P. King, David Baker, Guido Silvestri, Andrew B. Ward, Darrell J. Irvine

    Izdano 2020
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  11. 11
    HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies

    HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies od Kimmo Rantalainen, Zachary T. Berndsen, Aleksandar Antanasijevic, Torben Schiffner, Xi Zhang, Wen-Hsin Lee, Jonathan L. Torres, Lei Zhang, A. Irimia, Jeffrey Copps, Kenneth Zhou, Young Do Kwon, William H. Law, Chaim A. Schramm, Raffaello Verardi, Shelly J. Krebs, Peter D. Kwong, Nicole A. Doria‐Rose, Ian A. Wilson, Michael B. Zwick, John R. Yates, William R. Schief, Andrew B. Ward

    Izdano 2020
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  12. 12
    B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models

    B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models od Deli Huang, Robert Abbott, Colin Havenar‐Daughton, Patrick Skog, Rita Al-Kolla, Bettina Gröschel, Tanya R. Blane, Sergey Menis, Jenny Tuyet Tran, Theresa C. Thinnes, Sabrina A. Volpi, Alessia Liguori, Torben Schiffner, Sophia M. Villegas, Oleksandr Kalyuzhniy, Mark Pintea, James E. Voss, Nicole Phelps, Ryan Tingle, Alberto R. Rodriguez, Greg Martin, Sergey Kupryianov, Allan C. deCamp, William R. Schief, David Nemazee, Shane Crotty

    Izdano 2020
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  13. 13
    Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors

    Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors od Jordan R. Willis, Zachary T. Berndsen, Mark Krystal, Jon M. Steichen, Torben Schiffner, Elise Landais, Alessia Liguori, Kalyuzhniy Oleksandr, Joel D. Allen, Sabyasachi Baboo, Oluwarotimi Omorodion, Jolene K. Diedrich, Xiaozhen Hu, Erik Georgeson, Nicole Phelps, Saman Eskandarzadeh, Bettina Gröschel, Michael Kubitz, Yumiko Adachi, Tina-Marie Mullin, Nushin Alavi, Samantha Falcone, Sunny Himansu, Andrea Carfı́, Ian A. Wilson, John R. Yates, James C. Paulson, Max Crispin, Andrew B. Ward, William R. Schief

    Izdano 2022
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  14. 14
    HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies

    HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies od Jon M. Steichen, Daniel W. Kulp, Talar Tokatlian, Amelia Escolano, Pia Dosenovic, Robyn L. Stanfield, Laura E. McCoy, Gabriel Ozorowski, Xiaozhen Hu, Oleksandr Kalyuzhniy, Bryan Briney, Torben Schiffner, Fernando Garcés, Natalia T. Freund, Alexander D. Gitlin, Sergey Menis, Erik Georgeson, Michael Kubitz, Yumiko Adachi, Meaghan Jones, Andrew A. Mutafyan, Dong Soo Yun, Christian T. Mayer, Andrew B. Ward, Dennis R. Burton, Ian A. Wilson, Darrell J. Irvine, M C Nussenzweig, William R. Schief

    Izdano 2016
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  15. 15
    Affinity gaps among B cells in germinal centers drive the selection of MPER precursors

    Affinity gaps among B cells in germinal centers drive the selection of MPER precursors od Rashmi Ray, Torben Schiffner, Xuesong Wang, Yu Yan, Kimmo Rantalainen, Chang‐Chun D. Lee, Shivang Parikh, Raphael A. Reyes, Gordon Dale, Ying‐Cing Lin, Simone Pecetta, Sophie Giguère, Olivia Swanson, Sven Kratochvil, Eleonora Melzi, Ivy Phung, Lisa Madungwe, Oleksandr Kalyuzhniy, John E. Warner, Stephanie R. Weldon, Ryan Tingle, Edward Lamperti, Kathrin H. Kirsch, Nicole Phelps, Erik Georgeson, Yumiko Adachi, Michael Kubitz, Usha Nair, Shane Crotty, Ian A. Wilson, William R. Schief, Facundo D. Batista

    Izdano 2024
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  16. 16
    Heterologous prime-boost vaccination drives early maturation of HIV broadly neutralizing antibody precursors in humanized mice

    Heterologous prime-boost vaccination drives early maturation of HIV broadly neutralizing antibody precursors in humanized mice od Christopher A. Cottrell, Xiaozhen Hu, Jeong Hyun Lee, Patrick Skog, Sai Luo, Claudia T. Flynn, Katherine McKenney, Jonathan Hurtado, Oleksandr Kalyuzhniy, Alessia Liguori, Jordan R. Willis, Elise Landais, Sebastian Raemisch, Xuejun Chen, Sabyasachi Baboo, Sunny Himansu, Jolene K. Diedrich, Hongying Duan, Cheng Cheng, Torben Schiffner, Daniel Bader, Daniel W. Kulp, Ryan Tingle, Erik Georgeson, Saman Eskandarzadeh, Nushin Alavi, Danny Lu, Troy Sincomb, Michael Kubitz, Tina-Marie Mullen, John R. Yates, James C. Paulson, John R. Mascola, Frederick W. Alt, Bryan Briney, Devin Sok, William R. Schief

    Izdano 2024
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  17. 17
    Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates

    Vaccine priming of rare HIV broadly neutralizing antibody precursors in nonhuman primates od Jon M. Steichen, Ivy Phung, Eugenia Salcedo, Gabriel Ozorowski, Jordan R. Willis, Sabyasachi Baboo, Alessia Liguori, Christopher A. Cottrell, Jonathan L. Torres, Patrick Madden, Krystal Manyuan, Henry J. Sutton, Jeong Hyun Lee, Oleksandr Kalyuzhniy, Joel D. Allen, Oscar L. Rodriguez, Yumiko Adachi, Tina-Marie Mullen, Erik Georgeson, Michael Kubitz, Alison Burns, Shawn Barman, Rohini Mopuri, Amanda Metz, Tasha K. Altheide, Jolene K. Diedrich, Swati Saha, Kaitlyn Shields, Steven E. Schultze, Melissa Smith, Torben Schiffner, Dennis R. Burton, Corey T. Watson, Steven E. Bosinger, Max Crispin, John R. Yates, James C. Paulson, Andrew B. Ward, Devin Sok, Shane Crotty, William R. Schief

    Izdano 2024
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  18. 18
    Vaccination with mRNA-encoded membrane-bound HIV Envelope trimer induces neutralizing antibodies in animal models

    Vaccination with mRNA-encoded membrane-bound HIV Envelope trimer induces neutralizing antibodies in animal models od Parham Ramezani-Rad, Christopher A. Cottrell, Ester Marina-Zárate, Alessia Liguori, Elise Landais, Jonathan L. Torres, Amber Myers, Jeong Hyun Lee, Sabyasachi Baboo, Claudia T. Flynn, Katherine McKenney, Eugenia Salcedo, Xiaoya Zhou, Oleksandr Kalyuzhniy, Erik Georgeson, Nicole Phelps, Danny Lu, Saman Eskandarzadeh, Sergey Menis, Michael Kubitz, Bettina Gröschel, Nushin Alavi, Abigail M. Jackson, Wen-Hsin Lee, Andy S Tran, Elana Ben‐Akiva, Katarzyna Kaczmarek Michaels, Jolene K. Diedrich, Chiamaka A. Enemuo, Vanessa Lewis, Arpan Pradhan, Sudhir Pai Kasturi, Torben Schiffner, Jon M. Steichen, Diane G. Carnathan, Sunny Himansu, John R. Yates, James C. Paulson, Gabriel Ozorowski, Darrell J. Irvine, Guido Silvestri, Devin Sok, Andrew B. Ward, Shane Crotty, William R. Schief

    Izdano 2025
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  19. 19
    Vaccination induces HIV broadly neutralizing antibody precursors in humans

    Vaccination induces HIV broadly neutralizing antibody precursors in humans od David J. Leggat, Kristen W. Cohen, Jordan R. Willis, William J. Fulp, Allan C. deCamp, Oleksandr Kalyuzhniy, Christopher A. Cottrell, Sergey Menis, Greg Finak, Lamar Ballweber-Fleming, Abhinaya Srikanth, Jason R. Plyler, Torben Schiffner, Alessia Liguori, Farhad Rahaman, Angela Lombardo, Vincent Philiponis, Rachael E. Whaley, Aaron Seese, Joshua Brand, Alexis M. Ruppel, Wesley Hoyland, Nicole L. Yates, LaTonya D. Williams, Kelli Greene, Hongmei Gao, Celia R. Mahoney, Martin Corcoran, Alberto Cagigi, Alison Taylor, David M. Brown, David R. Ambrozak, Troy Sincomb, Xiaozhen Hu, Ryan Tingle, Erik Georgeson, Saman Eskandarzadeh, Nushin Alavi, Danny Lu, Tina-Marie Mullen, Michael Kubitz, Bettina Gröschel, Janine Maenza, Orpheus Kolokythas, Nadia J. Khati, Jeffrey M. Bethony, Shane Crotty, Mario Roederer, Gunilla B. Karlsson Hedestam, Georgia D. Tomaras, David C. Montefiori, David Diemert, Richard A. Koup, Dagna Laufer, M. Juliana McElrath, Adrian B. McDermott, William R. Schief

    Izdano 2022
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  20. 20
    Vaccination induces broadly neutralizing antibody precursors to HIV gp41

    Vaccination induces broadly neutralizing antibody precursors to HIV gp41 od Torben Schiffner, Ivy Phung, Rashmi Ray, A. Irimia, Ming Tian, Olivia Swanson, Jeong Hyun Lee, Chang‐Chun D. Lee, Ester Marina-Zárate, So Yeon Cho, Jiachen Huang, Gabriel Ozorowski, Patrick Skog, Andreia M. Serra, Kimmo Rantalainen, Joel D. Allen, Sabyasachi Baboo, Oscar L. Rodriguez, Sunny Himansu, Jianfu Zhou, Jonathan Hurtado, Claudia T. Flynn, Katherine McKenney, Colin Havenar‐Daughton, Swati Saha, Kaitlyn Shields, Steven Schultze, Melissa Smith, C. Jason Liang, Laura Toy, Simone Pecetta, Ying‐Cing Lin, Jordan R. Willis, Fabian Sesterhenn, Daniel W. Kulp, Xiaozhen Hu, Christopher A. Cottrell, Xiaoya Zhou, Jennifer Ruiz, Xuesong Wang, Usha Nair, Kathrin H. Kirsch, Hwei-Ling Cheng, Jillian Davis, Oleksandr Kalyuzhniy, Alessia Liguori, Jolene K. Diedrich, Julia T. Ngo, Vanessa Lewis, Nicole Phelps, Ryan Tingle, Skye Spencer, Erik Georgeson, Yumiko Adachi, Michael Kubitz, Saman Eskandarzadeh, Marc‐André Elsliger, Rama Rao Amara, Elise Landais, Bryan Briney, Dennis R. Burton, Diane G. Carnathan, Guido Silvestri, Corey T. Watson, John R. Yates, James C. Paulson, Max Crispin, Gevorg Grigoryan, Andrew B. Ward, Devin Sok, Frederick W. Alt, Ian A. Wilson, Facundo D. Batista, Shane Crotty, William R. Schief

    Izdano 2024
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