Výsledky vyhledávání - Tomoya Isobe

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  1. 1
    Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner

    Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner Autor Meng Wang, Laura T. L. Brandt, Xiaonan Wang, Holly Russell, Emily Mitchell, Ashley N. Kamimae-Lanning, Jill M. Brown, Felix A. Dingler, Juan I. Garaycoechea, Tomoya Isobe, Sarah Kinston, Muxin Gu, George S. Vassiliou, Nicola K. Wilson, Berthold Göttgens, Ketan J. Patel

    Vydáno 2023
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  2. 2
    Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment

    Mitotic perturbation is a key mechanism of action of decitabine in myeloid tumor treatment Autor Tomohiro Yabushita, Takumi Chinen, Atsuya Nishiyama, Shuhei Asada, Ruka Shimura, Tomoya Isobe, Keita Yamamoto, Naru Sato, Yutaka Enomoto, Yosuke Tanaka, Tomofusa Fukuyama, Hitoshi Satoh, Keiko Kato, Kaori Saitoh, Takamasa Ishikawa, Tomoyoshi Soga, Yasuhito Nannya, Tatsuo Fukagawa, Makoto Nakanishi, Daiju Kitagawa, Toshio Kitamura, Susumu Goyama

    Vydáno 2023
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  3. 3
    Landscape of driver mutations and their clinical impacts in pediatric B-cell precursor acute lymphoblastic leukemia

    Landscape of driver mutations and their clinical impacts in pediatric B-cell precursor acute lymphoblastic leukemia Autor Hiroo Ueno, Kenichi Yoshida, Yusuke Shiozawa, Yasuhito Nannya, Yuka Iijima‐Yamashita, Nobutaka Kiyokawa, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Tomoya Isobe, Masafumi Seki, Shunsuke Kimura, Hideki Makishima, Masahiro Nakagawa, Nobuyuki Kakiuchi, Keisuke Kataoka, Tetsuichi Yoshizato, Dai Nishijima, Takao Deguchi, Kentaro Ohki, Atsushi Sato, Hiroyuki Takahashi, Yoshiko Hashii, Sadao Tokimasa, Junichi Hara, Yoshiyuki Kosaka, Koji Kato, Takeshi Inukai, Junko Takita, Toshihiko Imamura, Satoru Miyano, Atsushi Manabe, Keizo Horibe, Seishi Ogawa, Masashi Sanada

    Vydáno 2020
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  4. 4
    NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity

    NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity Autor Takaya Moriyama, Rina Nishii, Virginia Pérez-Andreu, Wenjian Yang, Federico Antillón‐Klussmann, Xujie Zhao, Ting-Nien Lin, Keito Hoshitsuki, Jacob Nersting, Kentaro Kihira, Ute Hofmann, Yoshihiro Komada, Motohiro Kato, J. Robert McCorkle, Lie Li, Katsuyoshi Koh, Cesar Najera, Shirley Kow‐Yin Kham, Tomoya Isobe, Zhiwei Chen, Edwynn Kean-Hui Chiew, Deepa Bhojwani, Cynthia Jeffries, Yan Lu, Matthias Schwab, Hiroto Inaba, Ching‐Hon Pui, Mary V. Relling, Atsushi Manabe, Hiroki Hori, Kjeld Schmiegelow, Allen Eng Juh Yeoh, William E. Evans, Jun J. Yang

    Vydáno 2016
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  5. 5
    Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets

    Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets Autor Masahiro Sekiguchi, Masafumi Seki, Tomoko Kawai, Kenichi Yoshida, Misa Yoshida, Tomoya Isobe, N. Hoshino, Ryota Shirai, Mio Tanaka, Ryota Souzaki, Kentaro Watanabe, Yuki Arakawa, Yasuhito Nannya, Hiromichi Suzuki, Yoichi Fujii, Keisuke Kataoka, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Teppei Shimamura, Yusuke Sato, Aiko Sato‐Otsubo, Shunsuke Kimura, Yasuo Kubota, Mitsuteru Hiwatari, Katsuyoshi Koh, Yasuhide Hayashi, Yutaka Kanamori, Mureo Kasahara, Kenichi Kohashi, Motohiro Kato, Takako Yoshioka, Kimikazu Matsumoto, Akira Oka, Tomoaki Taguchi, Masashi Sanada, Yukichi Tanaka, Satoru Miyano, Kenichiro Hata, Seishi Ogawa, Junko Takita

    Vydáno 2020
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  6. 6
    Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia

    Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia Autor Tomoya Isobe, Masatoshi Takagi, Aiko Sato‐Otsubo, Akira Nishimura, Genta Nagae, Chika Yamagishi, Moe Tamura, Yosuke Tanaka, Shuhei Asada, Reina Takeda, Akiho Tsuchiya, Xiaonan Wang, Kenichi Yoshida, Yasuhito Nannya, Hiroo Ueno, Ryo Akazawa, Itaru Kato, Takashi Mikami, Kentaro Watanabe, Masahiro Sekiguchi, Masafumi Seki, Shunsuke Kimura, Mitsuteru Hiwatari, Motohiro Kato, Shiro Fukuda, Kenji Tatsuno, Shuichi Tsutsumi, Akinori Kanai, Toshiya Inaba, Yusuke Shiozawa, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Rishi S. Kotecha, Mark N. Cruickshank, Fumihiko Ishikawa, Tomohiro Morio, Mariko Eguchi, Takao Deguchi, Nobutaka Kiyokawa, Yuki Arakawa, Katsuyoshi Koh, Yuki Aoki, Takashi Ishihara, Daisuke Tomizawa, Takako Miyamura, Eiichi Ishii, Shuki Mizutani, Nicola K. Wilson, Berthold Göttgens, Satoru Miyano, Toshio Kitamura, Susumu Goyama, Akihiko Yokoyama, Hiroyuki Aburatani, Seishi Ogawa, Junko Takita

    Vydáno 2022
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