Resultados da busca por Autor :: APM

1

An investigational RNAi therapeutic targeting Factor XII (ALN-F12) for the treatment of hereditary angioedema por Jingxuan Liu, June Qin, Anna Borodovsky, Timothy Racie, Adam Castoreno, Mark K. Schlegel, Martin A. Maier, Tracy Zimmerman, Kevin Fitzgerald, James Butler, Akin Akinc

Publicado em 2018

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An Investigational RNAi Therapeutic Targeting Glycolate Oxidase Reduces Oxalate Production in Models of Primary Hyperoxaluria por Abigail Liebow, Xingsheng Li, Timothy Racie, Julia Hettinger, Brian R. Bettencourt, Nader Najafian, Patrick Haslett, Kevin Fitzgerald, Ross P. Holmes, David V. Erbe, William Querbes, John Knight

Publicado em 2016

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Lipid-like materials for low-dose, in vivo gene silencing por Kevin T. Love, Kerry P. Mahon, Christopher G. Levins, Kathryn A. Whitehead, William Querbes, J. Robert Dorkin, June Qin, William Cantley, Liu Liang Qin, Timothy Racie, Maria Frank-Kamenetsky, Ka Ning Yip, Rene Alvarez, Dinah W.Y. Sah, Antonin de Fougerolles, Kevin Fitzgerald, Victor Koteliansky, Akin Akinc, Róbert Langer, Daniel G. Anderson

Publicado em 2010

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4

Investigating the pharmacodynamic durability of GalNAc–siRNA conjugates por Christopher R. Brown, Swati Gupta, June Qin, Timothy Racie, He Guo, Scott Lentini, Ryan J. Malone, Mikyung Yu, Shigeo Matsuda, Svetlana Shulga‐Morskaya, Anil V. Nair, Christopher S. Theile, Karyn Schmidt, Azar Shahraz, Varun Goel, Rubina Parmar, Ivan Zlatev, Mark K. Schlegel, Jayaprakash K. Nair, Muthusamy Jayaraman, Muthiah Manoharan, Dennis Brown, Martin A. Maier, Vasant Jadhav

Publicado em 2020

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Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms por Akin Akinc, William Querbes, Soma De, June Qin, Maria Frank-Kamenetsky, K. N. Jayaprakash, Muthusamy Jayaraman, Kallanthottathil G. Rajeev, William Cantley, J. Robert Dorkin, James S. Butler, LiuLiang Qin, Timothy Racie, Andrew Sprague, Eugenio Fava, Anja Zeigerer, Michael J. Hope, Marino Zerial, Dinah W.Y. Sah, Kevin Fitzgerald, Mark A. Tracy, Muthiah Manoharan, Victor Koteliansky, Antonin de Fougerolles, Martin A. Maier

Publicado em 2010

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A combinatorial library of lipid-like materials for delivery of RNAi therapeutics por Akin Akinc, Andreas Zumbuehl, Michael S. Goldberg, Elizaveta S. Leshchiner, Valentina Busini, Naushad Hossain, Sergio Bacallado, David N. Nguyen, Jason Fuller, Rene Alvarez, Anna Borodovsky, Todd Borland, Rainer Constien, Antonin de Fougerolles, J. Robert Dorkin, K. N. Jayaprakash, Muthusamy Jayaraman, Matthias John, Victor Koteliansky, Muthiah Manoharan, Lubomir V. Nechev, June Qin, Timothy Racie, Denitza Raitcheva, Kallanthottathil G. Rajeev, Dinah W.Y. Sah, Jürgen Soutschek, Ivanka Toudjarska, Hans‐Peter Vornlocher, Tracy Zimmermann, Róbert Langer, Daniel G. Anderson

Publicado em 2008

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Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates por Maria Frank-Kamenetsky, Aldo Grefhorst, Norma N. Anderson, Timothy Racie, Birgit Bramlage, Akin Akinc, David Butler, Klaus Charissé, Robert Dorkin, Yupeng Fan, Christina Gamba‐Vitalo, Philipp Hadwiger, Muthusamy Jayaraman, Matthias John, K. N. Jayaprakash, Martin A. Maier, Lubomir V. Nechev, Kallanthottathil G. Rajeev, Timothy Read, Ingo Röhl, Jürgen Soutschek, Pamela Tan, Jamie Wong, Gang Wang, Tracy Zimmermann, Antonin de Fougerolles, Hans-Peter Vornlocher, Róbert Langer, Daniel G. Anderson, Muthiah Manoharan, Victor Koteliansky, Jay D. Horton, Kevin Fitzgerald

Publicado em 2008

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From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus por Yan V. Sun, Alanna Strong, Maria Frank-Kamenetsky, Noemi E Lee, Tim Ahfeldt, Katherine V. Sachs, Xiaoyu Li, Hui Li, Nicolas Kuperwasser, Vera M. Ruda, James P. Pirruccello, Brian Muchmore, Ludmila Prokunina‐Olsson, Jennifer L. Hall, Eric E. Schadt, Carlos R. Morales, Sissel Lund‐Katz, Michael C. Phillips, Jamie Wong, William Cantley, Timothy Racie, Kenechi G. Ejebe, Marju Orho‐Melander, Olle Melander, Victor Koteliansky, Kevin Fitzgerald, Ronald M. Krauss, Chad A. Cowan, Sekar Kathiresan, Daniel J. Rader

Publicado em 2010

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Expanding RNAi therapeutics to extrahepatic tissues with lipophilic conjugates por Kirk Brown, Jayaprakash K. Nair, Maja M. Janas, Yesseinia I. Angleró-Rodríguez, Lan Dang, Haiyan Peng, Christopher S. Theile, Elena Castellanos-Rizaldos, Christopher R. Brown, Donald J. Foster, Jeffrey C. Kurz, Jeffrey C. Allen, Rajanikanth J Maganti, Jing Li, Shigeo Matsuda, Matthew Stricos, Tyler Chickering, Michelle Jung, Kelly Wassarman, Jeff Rollins, Lauren Blair Woods, Alex Kelin, Dale C. Guenther, Melissa W. Mobley, John R. Petrulis, Robin McDougall, Timothy Racie, Jessica Bombardier, Diana Cha, Saket Agarwal, Lei Johnson, Yongfeng Jiang, Scott Lentini, Jason A. Gilbert, Tuyen Nguyen, Samantha Chigas, Sarah LeBlanc, Urjana Poreci, Anne Kasper, Arlin B. Rogers, Saeho Chong, Wendell Davis, Jessica E. Sutherland, Adam Castoreno, Stuart Milstein, Mark K. Schlegel, Ivan Zlatev, Klaus Charissé, Mark Keating, Muthiah Manoharan, Kevin Fitzgerald, Jing‐Tao Wu, Martin A. Maier, Vasant Jadhav

Publicado em 2022

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