Resultats de la cerca - Timothy D. W. Claridge

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  1. 1
    How formaldehyde reacts with amino acids

    How formaldehyde reacts with amino acids per Jos J. A. G. Kamps, Richard J. Hopkinson, Christopher J. Schofield, Timothy D. W. Claridge

    Publicat 2019
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  2. 2
    Impact of Multiple Hydrogen Bonds with Fluoride on Catalysis: Insight from NMR Spectroscopy

    Impact of Multiple Hydrogen Bonds with Fluoride on Catalysis: Insight from NMR Spectroscopy per Francesco Ibba, Gabriele Pupo, Amber L. Thompson, John M. Brown, Timothy D. W. Claridge, Véronique Gouverneur

    Publicat 2020
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  3. 3
    The longitudinal cerebrospinal fluid metabolomic profile of amyotrophic lateral sclerosis

    The longitudinal cerebrospinal fluid metabolomic profile of amyotrophic lateral sclerosis per Elizabeth Gray, James R. Larkin, Timothy D. W. Claridge, Kevin Talbot, Nicola R. Sibson, Martin R. Turner

    Publicat 2015
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  4. 4
    Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the β-carbon of asparagine-803

    Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the β-carbon of asparagine-803 per Luke A. McNeill, Kirsty S. Hewitson, Timothy D. W. Claridge, Jürgen Seibel, Louise Horsfall, Christopher J. Schofield

    Publicat 2002
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  5. 5
    Monitoring Conformational Changes in the NDM‐1 Metallo‐β‐lactamase by <sup>19</sup>F NMR Spectroscopy

    Monitoring Conformational Changes in the NDM‐1 Metallo‐β‐lactamase by <sup>19</sup>F NMR Spectroscopy per Anna M. Rydzik, Jürgen Brem, Sander S. van Berkel, Inga Pfeffer, Anne Makena, Timothy D. W. Claridge, Christopher J. Schofield

    Publicat 2014
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  6. 6
    Synthetic Control of Retinal Photochemistry and Photophysics in Solution

    Synthetic Control of Retinal Photochemistry and Photophysics in Solution per Giovanni Bassolino, Tina Sovdat, Matz Liebel, Christoph Schnedermann, Barbara Odell, Timothy D. W. Claridge, Philipp Kukura, Stephen P. Fletcher

    Publicat 2014
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  7. 7
    Plasma Nuclear Magnetic Resonance Metabolomics Discriminates Between High and Low Endoscopic Activity and Predicts Progression in a Prospective Cohort of Patients With Ulcerative Colitis

    Plasma Nuclear Magnetic Resonance Metabolomics Discriminates Between High and Low Endoscopic Activity and Predicts Progression in a Prospective Cohort of Patients With Ulcerative C... per Fay Probert, Alissa Walsh, Marta Jagielowicz, Tianrong Yeo, Timothy D. W. Claridge, Alison Simmons, Simon Travis, Daniel C. Anthony

    Publicat 2018
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  8. 8
    NMR analyses on<i>N</i>-hydroxymethylated nucleobases – implications for formaldehyde toxicity and nucleic acid demethylases

    NMR analyses on<i>N</i>-hydroxymethylated nucleobases – implications for formaldehyde toxicity and nucleic acid demethylases per Shifali Shishodia, D. Zhang, Afaf H. El‐Sagheer, Tom Brown, Timothy D. W. Claridge, Christopher J. Schofield, Richard J. Hopkinson

    Publicat 2018
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  9. 9
    Reporter Ligand NMR Screening Method for 2-Oxoglutarate Oxygenase Inhibitors

    Reporter Ligand NMR Screening Method for 2-Oxoglutarate Oxygenase Inhibitors per Ivanhoe K. H. Leung, Marina Demetriades, A. Hardy, Clarisse Lejeune, Tristan J. Smart, Andrea Szöllössi, Akane Kawamura, Christopher J. Schofield, Timothy D. W. Claridge

    Publicat 2012
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  10. 10
    Interaction of Avibactam with Class B Metallo-β-Lactamases

    Interaction of Avibactam with Class B Metallo-β-Lactamases per Martine I. Abboud, Christian Damblon, Jürgen Brem, Nicolas Smargiasso, Paola Sandra Mercuri, Bernard Gilbert, Anna M. Rydzik, Timothy D. W. Claridge, Christopher J. Schofield, Jean‐Marie Frère

    Publicat 2016
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  11. 11
    Factor‐inhibiting hypoxia‐inducible factor (FIH) catalyses the post‐translational hydroxylation of histidinyl residues within ankyrin repeat domains

    Factor‐inhibiting hypoxia‐inducible factor (FIH) catalyses the post‐translational hydroxylation of histidinyl residues within ankyrin repeat domains per Ming Yang, Rasheduzzaman Chowdhury, Wei Ge, Refaat B. Hamed, M.A. McDonough, Timothy D. W. Claridge, Benedikt M. Kessler, Matthew E. Cockman, Peter J. Ratcliffe, Christopher J. Schofield

    Publicat 2011
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  12. 12
    Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases

    Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases per Hanna Tarhonskaya, Anna M. Rydzik, Ivanhoe K. H. Leung, Nikita D. Loik, Mun Chiang Chan, Akane Kawamura, James McCullagh, Timothy D. W. Claridge, Emily Flashman, Christopher J. Schofield

    Publicat 2014
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  13. 13
    Asparagine and Aspartate Hydroxylation of the Cytoskeletal Ankyrin Family Is Catalyzed by Factor-inhibiting Hypoxia-inducible Factor

    Asparagine and Aspartate Hydroxylation of the Cytoskeletal Ankyrin Family Is Catalyzed by Factor-inhibiting Hypoxia-inducible Factor per Ming Yang, Wei Ge, Rasheduzzaman Chowdhury, Timothy D. W. Claridge, Holger Kramer, Bernhard Schmierer, M.A. McDonough, Lingzhi Gong, Benedikt M. Kessler, Peter J. Ratcliffe, Mathew L. Coleman, Christopher J. Schofield

    Publicat 2010
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  14. 14
    A type 2 biomarker separates relapsing-remitting from secondary progressive multiple sclerosis

    A type 2 biomarker separates relapsing-remitting from secondary progressive multiple sclerosis per Alex M. Dickens, James R. Larkin, Julian L. Griffin, Ana Cavey, Lucy Matthews, Martin R. Turner, Gordon Wilcock, Benjamin G. Davis, Timothy D. W. Claridge, Jacqueline Palace, Daniel C. Anthony, Nicola R. Sibson

    Publicat 2014
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  15. 15
    Cerebrospinal fluid metabolomics implicate bioenergetic adaptation as a neural mechanism regulating shifts in cognitive states of HIV-infected patients

    Cerebrospinal fluid metabolomics implicate bioenergetic adaptation as a neural mechanism regulating shifts in cognitive states of HIV-infected patients per Alex M. Dickens, Daniel C. Anthony, Reena Deutsch, Michelle M. Mielke, Timothy D. W. Claridge, Igor Grant, Donald Franklin, Debra Rosario, Thomas D. Marcotte, Scott Letendre, Justin C. McArthur, Norman J. Haughey

    Publicat 2015
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  16. 16
    Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases

    Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases per Rasheduzzaman Chowdhury, Ivanhoe K. H. Leung, Ya‐Min Tian, Martine I. Abboud, Wei Ge, Cármen Domene, François‐Xavier Cantrelle, Isabelle Landrieu, A. Hardy, Christopher W. Pugh, Peter J. Ratcliffe, Timothy D. W. Claridge, Christopher J. Schofield

    Publicat 2016
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  17. 17
    Metabolomic Biomarkers in Blood Samples Identify Cancers in a Mixed Population of Patients with Nonspecific Symptoms

    Metabolomic Biomarkers in Blood Samples Identify Cancers in a Mixed Population of Patients with Nonspecific Symptoms per James R. Larkin, Susan Anthony, Vanessa A. Johanssen, Tianrong Yeo, Megan Sealey, Abi G. Yates, Claire Friedemann Smith, Timothy D. W. Claridge, Brian D Nicholson, Julie‐Ann Moreland, Fergus Gleeson, Nicola R. Sibson, Daniel C. Anthony, Fay Probert

    Publicat 2022
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  18. 18
    Bending a photonic wire into a ring

    Bending a photonic wire into a ring per Henrik Gotfredsen, Jie‐Ren Deng, Jeff M. Van Raden, Marcello Righetto, Janko Hergenhahn, M Clarke, Abigail Bellamy-Carter, Jack Hart, James N. O’Shea, Timothy D. W. Claridge, Fernanda Duarte, Alex Saywell, Laura M. Herz, Harry L. Anderson

    Publicat 2022
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  19. 19
    Metabolomics reveals distinct, antibody-independent, molecular signatures of MS, AQP4-antibody and MOG-antibody disease

    Metabolomics reveals distinct, antibody-independent, molecular signatures of MS, AQP4-antibody and MOG-antibody disease per Maciej Juryńczyk, Fay Probert, Tianrong Yeo, George Tackley, Timothy D. W. Claridge, Ana Cavey, Mark Woodhall, Siddharth Arora, Torsten Winkler, Eric Schiffer, Angela Vincent, Gabriele C. DeLuca, Nicola R. Sibson, Maria Isabel Leite, Patrick Waters, Daniel C. Anthony, Jacqueline Palace

    Publicat 2017
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  20. 20
    Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain

    Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain per Mun Chiang Chan, Onur Atasoylu, Emma J. Hodson, Anthony Tumber, Ivanhoe K. H. Leung, Rasheduzzaman Chowdhury, Verónica Gómez‐Pérez, Marina Demetriades, Anna M. Rydzik, James P. Holt‐Martyn, Ya‐Min Tian, Tammie Bishop, Timothy D. W. Claridge, Akane Kawamura, Christopher W. Pugh, Peter J. Ratcliffe, Christopher J. Schofield

    Publicat 2015
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