Sökresultat - Tilman Brummer

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  1. 1
    The role of the MDM2/p53 axis in antitumor immune responses

    The role of the MDM2/p53 axis in antitumor immune responses av Tilman Brummer, Robert Zeiser

    Publicerad 2023
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  2. 2
    Function, regulation and pathological roles of the Gab/DOS docking proteins

    Function, regulation and pathological roles of the Gab/DOS docking proteins av Franziska U. Wöhrle, Roger J. Daly, Tilman Brummer

    Publicerad 2009
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  3. 3
    Immune modulatory effects of oncogenic KRAS in cancer

    Immune modulatory effects of oncogenic KRAS in cancer av Shaima’a Hamarsheh, Olaf Groß, Tilman Brummer, Robert Zeiser

    Publicerad 2020
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  4. 4
    Onco-immunomodulatory properties of pharmacological interference with RAS-RAF-MEK-ERK pathway hyperactivation

    Onco-immunomodulatory properties of pharmacological interference with RAS-RAF-MEK-ERK pathway hyperactivation av Thomas Yul Avery, Natalie Köhler, Robert Zeiser, Tilman Brummer, Dietrich Alexander Ruess

    Publicerad 2022
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  5. 5
    Charting co-mutation patterns associated with actionable drivers in intrahepatic cholangiocarcinoma

    Charting co-mutation patterns associated with actionable drivers in intrahepatic cholangiocarcinoma av Gajanan Kendre, Karthikeyan Murugesan, Tilman Brummer, Oreste Segatto, Anna Saborowski, Arndt Vogel

    Publicerad 2022
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  6. 6
    Adenosine and cAMP are potent inhibitors of the NF‐κB pathway downstream of immunoreceptors

    Adenosine and cAMP are potent inhibitors of the NF‐κB pathway downstream of immunoreceptors av Susana Minguet, Michael Huber, Lisa Rosenkranz, Wolfgang W. Schamel, Michael Reth, Tilman Brummer

    Publicerad 2004
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  7. 7
    The EMT-activator ZEB1 induces bone metastasis associated genes including BMP-inhibitors

    The EMT-activator ZEB1 induces bone metastasis associated genes including BMP-inhibitors av Kerstin Mock, Bogdan‐Tiberius Preca, Tilman Brummer, Simone Brabletz, Marc P. Stemmler, Thomas Brabletz

    Publicerad 2015
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  8. 8
    Increased Proliferation and Altered Growth Factor Dependence of Human Mammary Epithelial Cells Overexpressing the Gab2 Docking Protein

    Increased Proliferation and Altered Growth Factor Dependence of Human Mammary Epithelial Cells Overexpressing the Gab2 Docking Protein av Tilman Brummer, Daniel Schramek, Vanessa M. Hayes, Haley L. Bennett, C. Elizabeth Caldon, Elizabeth A. Musgrove, Roger J. Daly

    Publicerad 2005
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  9. 9
    Strong negative feedback from Erk to Raf confers robustness to MAPK signalling

    Strong negative feedback from Erk to Raf confers robustness to MAPK signalling av Raphaela Fritsche‐Guenther, Franziska Witzel, Anja Sieber, Ricarda Herr, Nadine Schmidt, Sandra Braun, Tilman Brummer, Christine Sers, Nils Blüthgen

    Publicerad 2011
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  10. 10
    Discrete cytosolic macromolecular <scp>BRAF</scp> complexes exhibit distinct activities and composition

    Discrete cytosolic macromolecular <scp>BRAF</scp> complexes exhibit distinct activities and composition av Britta Diedrich, Kristoffer T. G. Rigbolt, Michael Röring, Ricarda Herr, Stéphanie Pébernard, Christine Gretzmeier, Robert F. Murphy, Tilman Brummer, Jörn Dengjel

    Publicerad 2017
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  11. 11
    ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types

    ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types av Waltraut Lehmann, Dirk Mossmann, Julia Kleemann, Kerstin Mock, Chris Meisinger, Tilman Brummer, Ricarda Herr, Simone Brabletz, Marc P. Stemmler, Thomas Brabletz

    Publicerad 2016
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  12. 12
    Insulin-like growth factor-1 receptor (IGF1R) as a novel target in chronic lymphocytic leukemia

    Insulin-like growth factor-1 receptor (IGF1R) as a novel target in chronic lymphocytic leukemia av Niuscha Yaktapour, Rudolf Übelhart, Julia Schüler, Konrad Aumann, Christine Dierks, Meike Burger, Dietmar Pfeifer, Hassan Jumaa, Hendrik Veelken, Tilman Brummer, Katja Zirlik

    Publicerad 2013
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  13. 13
    A self-enforcing CD44s/ZEB1 feedback loop maintains EMT and stemness properties in cancer cells

    A self-enforcing CD44s/ZEB1 feedback loop maintains EMT and stemness properties in cancer cells av Bogdan‐Tiberius Preca, Karolina Bajdak-Rusinek, Kerstin Mock, Vignesh Sundararajan, Jessica Pfannstiel, Jochen Maurer, Ulrich F. Wellner, Ulrich T. Hopt, Tilman Brummer, Simone Brabletz, Thomas Brabletz, Marc P. Stemmler

    Publicerad 2015
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  14. 14
    Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling

    Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling av Michael Röring, Ricarda Herr, Gina J. Fiala, Katharina Heilmann, Sandra Braun, Anja E. Eisenhardt, Sebastian Halbach, David Capper, Andreas von Deimling, Wolfgang W. Schamel, Darren N. Saunders, Tilman Brummer

    Publicerad 2012
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  15. 15
    Cathepsin D deficiency in mammary epithelium transiently stalls breast cancer by interference with mTORC1 signaling

    Cathepsin D deficiency in mammary epithelium transiently stalls breast cancer by interference with mTORC1 signaling av Stephanie Ketterer, Julia Mitschke, Anett Ketscher, Manuel Schlimpert, Wilfried Reichardt, Natascha Baeuerle, Maria Elena Hess, Patrick Metzger, Melanie Boerries, Christoph Peters, Bernd Kammerer, Tilman Brummer, Florian Steinberg, Thomas Reinheckel

    Publicerad 2020
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  16. 16
    Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein

    Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein av Tilman Brummer, Mark Larance, Maria Teresa Herrera Abreu, Ruth J. Lyons, Paul Timpson, Christoph H. Emmerich, Emmy D.G. Fleuren, Gillian M. Lehrbach, Daniel Schramek, Michael Guilhaus, David E. James, Roger J. Daly

    Publicerad 2008
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  17. 17
    B-Raf Inhibitors Induce Epithelial Differentiation in<i>BRAF</i>-Mutant Colorectal Cancer Cells

    B-Raf Inhibitors Induce Epithelial Differentiation in<i>BRAF</i>-Mutant Colorectal Cancer Cells av Ricarda Herr, M. Köhler, Hana Andrlová, Florian Weinberg, Yvonne Möller, Sebastian Halbach, Lisa Lutz, Justin Mastroianni, Martin Klose, Nicola Bittermann, Silke Kowar, Robert Zeiser, Monilola A. Olayioye, Silke Laßmann, Hauke Busch, Melanie Boerries, Tilman Brummer

    Publicerad 2014
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  18. 18
    BRAF inhibitor–associated ERK activation drives development of chronic lymphocytic leukemia

    BRAF inhibitor–associated ERK activation drives development of chronic lymphocytic leukemia av Niuscha Yaktapour, Frank Meiß, Justin Mastroianni, Thorsten Zenz, Hana Andrlová, Nimitha R. Mathew, Rainer Claus, Barbara Hutter, Stefan Fröhling, Benedikt Brors, Dietmar Pfeifer, Milena Pantić, Ingrid Bartsch, Timo S. Spehl, Philipp T. Meyer, Justus Duyster, Katja Zirlik, Tilman Brummer, Robert Zeiser

    Publicerad 2014
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  19. 19
    The Atypical Kinase RIOK1 Promotes Tumor Growth and Invasive Behavior

    The Atypical Kinase RIOK1 Promotes Tumor Growth and Invasive Behavior av Florian Weinberg, Nadine Reischmann, Lisa Fauth, Sanaz Taromi, Justin Mastroianni, M. Köhler, Sebastian Halbach, Andrea C. Becker, Niantao Deng, Tatjana Schmitz, Franziska Maria Uhl, Nicola Herbener, Bianca Riedel, Fabian Beier, Alexander Swarbrick, Silke Laßmann, Jörn Dengjel, Robert Zeiser, Tilman Brummer

    Publicerad 2017
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  20. 20
    MicroRNA-146a reduces MHC-II expression via targeting JAK/STAT signaling in dendritic cells after stem cell transplantation

    MicroRNA-146a reduces MHC-II expression via targeting JAK/STAT signaling in dendritic cells after stem cell transplantation av Natalie Stickel, Kathrin Hanke, Dominik Marschner, Gabriele Prinz, M. Köhler, Wolfgang Melchinger, Dietmar Pfeifer, Annette Schmitt‐Graeff, Tilman Brummer, Annkristin Heine, Peter Brossart, Dominik Wolf‎, Nikolas von Bubnoff, Jürgen Finke, Justus Duyster, James L.M. Ferrara, Ulrich Salzer, Robert Zeiser

    Publicerad 2017
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