Søgeresultater - Tianyuan Lu

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  1. 1
    Circulating Proteins Influencing Psychiatric Disease: A Mendelian Randomization Study

    Circulating Proteins Influencing Psychiatric Disease: A Mendelian Randomization Study af Tianyuan Lu, Vincenzo Forgetta, Celia M.T. Greenwood, Sirui Zhou, J. Brent Richards

    Udgivet 2022
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    Artigo
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  2. 2
    eXclusionarY: 10 years later, where are the sex chromosomes in GWASs?

    eXclusionarY: 10 years later, where are the sex chromosomes in GWASs? af Lei Sun, Zhong Wang, Tianyuan Lu, Teri A. Manolio, Andrew D. Paterson

    Udgivet 2023
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    Revisão
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  3. 3
    SharePro: an accurate and efficient genetic colocalization method accounting for multiple causal signals

    SharePro: an accurate and efficient genetic colocalization method accounting for multiple causal signals af Wenmin Zhang, Tianyuan Lu, Robert Sladek, Yue Li, Hamed S. Najafabadi, Josée Dupuis

    Udgivet 2024
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  4. 4
    Individuals with common diseases but with a low polygenic risk score could be prioritized for rare variant screening

    Individuals with common diseases but with a low polygenic risk score could be prioritized for rare variant screening af Tianyuan Lu, Sirui Zhou, Haoyu Wu, Vincenzo Forgetta, Celia M.T. Greenwood, J. Brent Richards

    Udgivet 2020
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    Artigo
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  5. 5
    Non-linear Mendelian randomization: evaluation of effect modification in the residual and doubly-ranked methods with simulated and empirical examples

    Non-linear Mendelian randomization: evaluation of effect modification in the residual and doubly-ranked methods with simulated and empirical examples af Fergus Hamilton, David A. Hughes, Tianyuan Lu, Zoltán Kutalik, Apostolos Gkatzionis, Kate Tilling, Fernando Pires Hartwig, George Davey Smith

    Udgivet 2025
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    Artigo
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  6. 6
    H3K27M in Gliomas Causes a One-Step Decrease in H3K27 Methylation and Reduced Spreading within the Constraints of H3K36 Methylation

    H3K27M in Gliomas Causes a One-Step Decrease in H3K27 Methylation and Reduced Spreading within the Constraints of H3K36 Methylation af Ashot S. Harutyunyan, Haifeng Chen, Tianyuan Lu, Cynthia Horth, Hamid Nikbakht, Brian Krug, Caterina Russo, Eric Bareke, Dylan M. Marchione, Mariel Coradin, Benjamin A. Garcia, Nada Jabado, Jacek Majewski

    Udgivet 2020
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    Artigo
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  7. 7
    Transcriptional reprogramming of skeletal muscle stem cells by the niche environment

    Transcriptional reprogramming of skeletal muscle stem cells by the niche environment af Felicia Lazure, Rick Farouni, Korin Sahinyan, Darren M. Blackburn, Aldo Hernández-Corchado, Gabrielle Perron, Tianyuan Lu, Adrien Osakwe, Jiannis Ragoussis, Colin Crist, Theodore J. Perkins, Arezu Jahani‐Asl, Hamed S. Najafabadi, Vahab D. Soleimani

    Udgivet 2023
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    Artigo
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  8. 8
    Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases

    Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases af Yiheng Chen, Tianyuan Lu, U. Pettersson, Isobel D. Stewart, Guillaume Butler‐Laporte, Tomoko Nakanishi, Agustin Cerani, Kevin Y. H. Liang, Satoshi Yoshiji, Julian Daniel Sunday Willett, Chen‐Yang Su, Parminder Raina, Celia M.T. Greenwood, Yossi Farjoun, Vincenzo Forgetta, Claudia Langenberg, Sirui Zhou, Claes Ohlsson, J. Brent Richards

    Udgivet 2023
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    Artigo
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  9. 9
    Improved prediction of fracture risk leveraging a genome-wide polygenic risk score

    Improved prediction of fracture risk leveraging a genome-wide polygenic risk score af Tianyuan Lu, Vincenzo Forgetta, Julyan Keller‐Baruch, Maria Nethander, Derrick Bennett, Marie Forest, Sahir Bhatnagar, Robin Walters, Kuang Lin, Zhengming Chen, Liming Li, Magnus K. Karlsson, Dan Mellström, Eric Orwoll, Eugène McCloskey, John А. Kanis, William D. Leslie, Robert Clarke, Claes Ohlsson, Celia M.T. Greenwood, J. Brent Richards

    Udgivet 2021
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    Artigo
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  10. 10
    HLA allele-calling using multi-ancestry whole-exome sequencing from the UK Biobank identifies 129 novel associations in 11 autoimmune diseases

    HLA allele-calling using multi-ancestry whole-exome sequencing from the UK Biobank identifies 129 novel associations in 11 autoimmune diseases af Guillaume Butler‐Laporte, Yossi Farjoun, Tomoko Nakanishi, Tianyuan Lu, Erik Abner, Yiheng Chen, Michael Hultström, Andres Metspalu, Lili Milani, Reedik Mägi, Mari Nelis, Georgi Hudjashov, Satoshi Yoshiji, Yann Ilboudo, Kevin Y. H. Liang, Chen‐Yang Su, Julian D. S. Willet, Tõnu Esko, Sirui Zhou, Vincenzo Forgetta, Daniel Taliun, J. Brent Richards

    Udgivet 2023
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    Artigo
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  11. 11
    Integrative proteogenomic analysis identifies COL6A3-derived endotrophin as a mediator of the effect of obesity on coronary artery disease

    Integrative proteogenomic analysis identifies COL6A3-derived endotrophin as a mediator of the effect of obesity on coronary artery disease af Satoshi Yoshiji, Tianyuan Lu, Guillaume Butler‐Laporte, Julia Carrasco-Zanini, Chen‐Yang Su, Yiheng Chen, Kevin Y. H. Liang, Julian Daniel Sunday Willett, Shidong Wang, Darin Adra, Yann Ilboudo, Takayoshi Sasako, Satoshi Koyama, Tetsushi Nakao, Vincenzo Forgetta, Yossi Farjoun, Hugo Zeberg, Sirui Zhou, Michael Hultström, Mitchell J. Machiela, Rama Kaalia, Hesam Dashti, Melina Claussnitzer, Jason Flannick, Nicholas J. Wareham, Vincent Mooser, Nicholas J. Timpson, Claudia Langenberg, J. Brent Richards

    Udgivet 2025
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    Artigo
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  12. 12
    Proteome-wide Mendelian randomization implicates nephronectin as an actionable mediator of the effect of obesity on COVID-19 severity

    Proteome-wide Mendelian randomization implicates nephronectin as an actionable mediator of the effect of obesity on COVID-19 severity af Satoshi Yoshiji, Guillaume Butler‐Laporte, Tianyuan Lu, Julian Daniel Sunday Willett, Chen‐Yang Su, Tomoko Nakanishi, David Morrison, Yiheng Chen, Kevin Y. H. Liang, Michael Hultström, Yann Ilboudo, Zaman Afrasiabi, Shanshan Lan, Naomi Duggan, Chantal DeLuca, Mitra Vaezi, Chris Tselios, Xiaoqing Xue, Meriem Bouab, Fangyi Shi, Lætitia Laurent, Hans Markus Münter, Marc Afilalo, Jonathan Afilalo, Vincent Mooser, Nicholas J. Timpson, Hugo Zeberg, Sirui Zhou, Vincenzo Forgetta, Yossi Farjoun, J. Brent Richards

    Udgivet 2023
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    Artigo
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