检索结果 - Tianfeng Xu

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  1. 1
    Design, Synthesis, and Biological Evaluation of Novel EGFR PROTACs Targeting Del19/T790M/C797S Mutation

    Design, Synthesis, and Biological Evaluation of Novel EGFR PROTACs Targeting Del19/T790M/C797S Mutation 由 Hualin Zhang, Ruliang Xie, Hawaa AI-furas, Yupeng Li, Qingxia Wu, Jian Li, Fang Xu, Tianfeng Xu

    出版 2022
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  2. 2
    Discovery of Highly Potent and Efficient PROTAC Degraders of Androgen Receptor (AR) by Employing Weak Binding Affinity VHL E3 Ligase Ligands

    Discovery of Highly Potent and Efficient PROTAC Degraders of Androgen Receptor (AR) by Employing Weak Binding Affinity VHL E3 Ligase Ligands 由 Xin Han, Lijie Zhao, Weiguo Xiang, Chong Qin, Bukeyan Miao, Tianfeng Xu, Mi Wang, Chao‐Yie Yang, Krishnapriya Chinnaswamy, Jeanne A. Stuckey, Shaomeng Wang

    出版 2019
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  3. 3
    Design, Synthesis, and Bioevaluation of Pyrido[2,3-<i>d</i>]pyrimidin-7-ones as Potent SOS1 Inhibitors

    Design, Synthesis, and Bioevaluation of Pyrido[2,3-<i>d</i>]pyrimidin-7-ones as Potent SOS1 Inhibitors 由 Meiying Liu, Guizhen Zhou, Wenhong Su, Yuejiao Gu, Mingshan Gao, Kun Wang, Ruifeng Huo, Yupeng Li, Zehui Zhou, Kaixian Chen, Mingyue Zheng, Sulin Zhang, Tianfeng Xu

    出版 2023
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  4. 4
    Engineered bioorthogonal POLY-PROTAC nanoparticles for tumour-specific protein degradation and precise cancer therapy

    Engineered bioorthogonal POLY-PROTAC nanoparticles for tumour-specific protein degradation and precise cancer therapy 由 Jing Gao, Bo Hou, Qiwen Zhu, Lei Yang, Xingyu Jiang, Zhifeng Zou, Xutong Li, Tianfeng Xu, Mingyue Zheng, Yi‐Hung Chen, Zhiai Xu, Huixiong Xu, Haijun Yu

    出版 2022
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  5. 5
    Discovery of M-808 as a Highly Potent, Covalent, Small-Molecule Inhibitor of the Menin–MLL Interaction with Strong <i>In Vivo</i> Antitumor Activity

    Discovery of M-808 as a Highly Potent, Covalent, Small-Molecule Inhibitor of the Menin–MLL Interaction with Strong <i>In Vivo</i> Antitumor Activity 由 Shilin Xu, Angelo Aguilar, Liyue Huang, Tianfeng Xu, Ke Zheng, Donna McEachern, Sally Przybranowski, C.L. Foster, Kaitlin P. Zawacki, Zhaomin Liu, Krishnapriya Chinnaswamy, Jeanne A. Stuckey, Shaomeng Wang

    出版 2020
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  6. 6
    Design of the First‐in‐Class, Highly Potent Irreversible Inhibitor Targeting the Menin‐MLL Protein–Protein Interaction

    Design of the First‐in‐Class, Highly Potent Irreversible Inhibitor Targeting the Menin‐MLL Protein–Protein Interaction 由 Shilin Xu, Angelo Aguilar, Tianfeng Xu, Ke Zheng, Liyue Huang, Jeanne A. Stuckey, Krishnapriya Chinnaswamy, Denzil Bernard, Ester Fernández‐Salas, Liu Liu, Mi Wang, Donna McEachern, Sally Przybranowski, C.L. Foster, Shaomeng Wang

    出版 2017
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  7. 7
    Discovery of <b>ERD-3111</b> as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader with Strong Antitumor Activity

    Discovery of <b>ERD-3111</b> as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader with Strong Antitumor Activity 由 Zhixiang Chen, Biao Hu, Rohan Kalyan Rej, Dimin Wu, Ranjan Kumar Acharyya, Mingliang Wang, Tianfeng Xu, Jianfeng Lü, Hoda Metwally, Yu Wang, Donna McEachern, Longchuan Bai, Christina L. Gersch, Meilin Wang, Wenjing Zhang, Qiuxia Li, Bo Wen, Duxin Sun, James M. Rae, Shaomeng Wang

    出版 2023
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  8. 8
    Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR + Human Prostate Cancer

    Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR + Human Prostate Cancer 由 Weiguo Xiang, Lijie Zhao, Xin Han, Tianfeng Xu, Steven Kregel, Mi Wang, Bukeyan Miao, Chong Qin, Mingliang Wang, Donna McEachern, Jianfeng Lü, Longchuan Bai, Chao‐Yie Yang, Paul D. Kirchhoff, John Takyi‐Williams, Lu Wang, Bo Wen, Duxin Sun, Mark A. Ator, Robert McKean, Arul M. Chinnaiyan, Shaomeng Wang

    出版 2023
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