Search Results - Thomas R. Nirschl

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  1. 1
    Sustained CD4<sup>+</sup>T cell-driven lymphopenia without a compensatory IL-7/IL-15 response among high-grade glioma patients treated with radiation and temozolomide

    Sustained CD4<sup>+</sup>T cell-driven lymphopenia without a compensatory IL-7/IL-15 response among high-grade glioma patients treated with radiation and temozolomide by Susannah G. Ellsworth, Ani Sarkis Balmanoukian, Ferdynand Kos, Christopher J. Nirschl, Thomas R. Nirschl, Stuart A. Grossman, Leo Luznik, Charles G. Drake

    Published 2014
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  2. 2
    Immunogenicity of prostate cancer is augmented by BET bromodomain inhibition

    Immunogenicity of prostate cancer is augmented by BET bromodomain inhibition by Wendy Mao, Ali Ghasemzadeh, Zachary T. Freeman, Aleksandar Z. Obradovic, Matthew G. Chaimowitz, Thomas R. Nirschl, Emily McKiernan, Srinivasan Yegnasubramanian, Charles G. Drake

    Published 2019
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  3. 3
    Stereotactic Radiation Therapy Augments Antigen-Specific PD-1–Mediated Antitumor Immune Responses via Cross-Presentation of Tumor Antigen

    Stereotactic Radiation Therapy Augments Antigen-Specific PD-1–Mediated Antitumor Immune Responses via Cross-Presentation of Tumor Antigen by Andrew B. Sharabi, Christopher J. Nirschl, Christina M. Kochel, Thomas R. Nirschl, Brian J. Francica, Esteban Velarde, Theodore L. DeWeese, Charles G. Drake

    Published 2014
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  4. 4
    Profiling serum antibodies with a pan allergen phage library identifies key wheat allergy epitopes

    Profiling serum antibodies with a pan allergen phage library identifies key wheat allergy epitopes by Daniel R. Monaco, Brandon Sie, Thomas R. Nirschl, Audrey C. Knight, Hugh A. Sampson, Anna Nowak‐Węgrzyn, Robert A. Wood, Robert G. Hamilton, Pamela A. Frischmeyer‐Guerrerio, H. Benjamin Larman

    Published 2021
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  5. 5
    Pre-radiation lymphocyte harvesting and post-radiation reinfusion in patients with newly diagnosed high grade gliomas

    Pre-radiation lymphocyte harvesting and post-radiation reinfusion in patients with newly diagnosed high grade gliomas by Jian L. Campian, Xiaobu Ye, Douglas E. Gladstone, Prakash Ambady, Thomas R. Nirschl, Ivan Borrello, Marc G. Golightly, Karen E. King, Matthias Holdhoff, Judith E. Karp, Charles G. Drake, Stuart A. Grossman

    Published 2015
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  6. 6
    Paucity of PD-L1 expression in prostate cancer: innate and adaptive immune resistance

    Paucity of PD-L1 expression in prostate cancer: innate and adaptive immune resistance by Allison Martin, Thomas R. Nirschl, Christopher J. Nirschl, Brian J. Francica, Christina M. Kochel, Adrie van Bokhoven, Alan K. Meeker, M. Scott Lucia, Robert A. Anders, Angelo M. De Marzo, Charles G. Drake

    Published 2015
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  7. 7
    Combining intratumoral Treg depletion with androgen deprivation therapy (ADT): preclinical activity in the Myc-CaP model

    Combining intratumoral Treg depletion with androgen deprivation therapy (ADT): preclinical activity in the Myc-CaP model by Ying‐Chun Shen, Ali Ghasemzadeh, Christina M. Kochel, Thomas R. Nirschl, Brian J. Francica, Zoila A. Lopez‐Bujanda, Maria A. Carrera Haro, Ada Tam, Robert A. Anders, Mark Selby, Alan J. Korman, Charles G. Drake

    Published 2017
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  8. 8
    Intravesical BCG Induces CD4+ T-Cell Expansion in an Immune Competent Model of Bladder Cancer

    Intravesical BCG Induces CD4+ T-Cell Expansion in an Immune Competent Model of Bladder Cancer by Max Kates, Thomas R. Nirschl, Nikolai A. Sopko, Hotaka Matsui, Christina M. Kochel, Leonardo Oliveira Reis, George J. Netto, Mohammad Obaidul Hoque, Noah M. Hahn, David J. McConkey, Alex S. Baras, Charles G. Drake, Trinity J. Bivalacqua

    Published 2017
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  9. 9
    Neoadjuvant Nivolumab in Patients with High-risk Nonmetastatic Renal Cell Carcinoma

    Neoadjuvant Nivolumab in Patients with High-risk Nonmetastatic Renal Cell Carcinoma by Michael A. Gorin, Hiten D. Patel, Steven P. Rowe, Noah M. Hahn, Hans J. Hammers, Alice Pons, Bruce J. Trock, Phillip M. Pierorazio, Thomas R. Nirschl, Daniela C. Salles, Julie E. Stein, Tamara L. Lotan, Janis M. Taube, Charles G. Drake, Mohamad E. Allaf

    Published 2021
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  10. 10
    Stereotactic Radiotherapy Increases Functionally Suppressive Regulatory T Cells in the Tumor Microenvironment

    Stereotactic Radiotherapy Increases Functionally Suppressive Regulatory T Cells in the Tumor Microenvironment by Yuki Muroyama, Thomas R. Nirschl, Christina M. Kochel, Zoila A. Lopez‐Bujanda, Debebe Theodros, Wendy Mao, Maria A. Carrera-Haro, Ali Ghasemzadeh, Ariel E. Marciscano, Esteban Velarde, Ada Tam, Christopher J. Thoburn, Muniza Uddin, Alan K. Meeker, Robert A. Anders, Drew M. Pardoll, Charles G. Drake

    Published 2017
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  11. 11
    A conserved intratumoral regulatory T cell signature identifies 4-1BB as a pan-cancer target

    A conserved intratumoral regulatory T cell signature identifies 4-1BB as a pan-cancer target by Zachary T. Freeman, Thomas R. Nirschl, Daniel H. Hovelson, Robert J. Johnston, John Engelhardt, Mark Selby, Christina M. Kochel, Ruth Y. Lan, Jingyi Zhai, Ali Ghasemzadeh, Anuj Gupta, Alyza Skaist, Sarah J. Wheelan, Hui Jiang, Alexander T. Pearson, Linda A. Snyder, Alan J. Korman, Scott A. Tomlins, Srinivasan Yegnasubramanian, Charles G. Drake

    Published 2020
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  12. 12
    Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma

    Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma by Mira Patel, Jennifer E. Kim, Debebe Theodros, Ada Tam, Esteban Velarde, Christina M. Kochel, Brian J. Francica, Thomas R. Nirschl, Ali Ghasemzadeh, Dimitrios Mathios, Sarah Harris‐Bookman, Christopher C. Jackson, Christina Jackson, Xiaobu Ye, Phuoc T. Tran, Betty Tyler, Vladimir Coric, M. J. Selby, Henry Brem, Charles G. Drake, Drew M. Pardoll, Michael Lim

    Published 2016
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  13. 13
    T-Cell Infiltration and Adaptive Treg Resistance in Response to Androgen Deprivation With or Without Vaccination in Localized Prostate Cancer

    T-Cell Infiltration and Adaptive Treg Resistance in Response to Androgen Deprivation With or Without Vaccination in Localized Prostate Cancer by Aleksandar Z. Obradovic, Matthew C. Dallos, Marianna Zahurak, Alan W. Partin, Edward M. Schaeffer, Ashley E. Ross, Mohamad E. Allaf, Thomas R. Nirschl, David Liu, Carolyn G. Chapman, Tanya O’Neal, Haiyi Cao, Jennifer N. Durham, Güneş Güner, Javier Baena-Del Valle, Onur Ertunç, Angelo M. De Marzo, Emmanuel S. Antonarakis, Charles G. Drake

    Published 2020
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  14. 14
    Elective Nodal Irradiation Attenuates the Combinatorial Efficacy of Stereotactic Radiation Therapy and Immunotherapy

    Elective Nodal Irradiation Attenuates the Combinatorial Efficacy of Stereotactic Radiation Therapy and Immunotherapy by Ariel E. Marciscano, Ali Ghasemzadeh, Thomas R. Nirschl, Debebe Theodros, Christina M. Kochel, Brian J. Francica, Yuki Muroyama, Robert A. Anders, Andrew B. Sharabi, Esteban Velarde, Wendy Mao, Kunal Chaudhary, Matthew G. Chaimowitz, John Wong, Mark Selby, Kent Thudium, Alan J. Korman, David Ulmert, Daniel L.J. Thorek, Theodore L. DeWeese, Charles G. Drake

    Published 2018
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  15. 15
    PD-L1 expression in medulloblastoma: an evaluation by subgroup

    PD-L1 expression in medulloblastoma: an evaluation by subgroup by Allison Martin, Christopher J. Nirschl, Magda J. Polanczyk, William R. Bell, Thomas R. Nirschl, Sarah Harris‐Bookman, Jillian Phallen, Jessica Hicks, Daniel Martínez, Aleksandra Ogurtsova, Haiying Xu, Lisa Sullivan, Alan K. Meeker, Eric H. Raabe, Kenneth J. Cohen, Charles G. Eberhart, Peter C. Burger, Mariarita Santi, Janis M. Taube, Drew M. Pardoll, Charles G. Drake, Michael Lim

    Published 2018
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  16. 16
    Systematic elucidation and pharmacological targeting of tumor-infiltrating regulatory T cell master regulators

    Systematic elucidation and pharmacological targeting of tumor-infiltrating regulatory T cell master regulators by Aleksandar Z. Obradovic, Casey R. Ager, Mikko Turunen, Thomas R. Nirschl, Mohsen Khosravi‐Maharlooei, Alina C. Iuga, Christopher M. Jackson, Srinivasan Yegnasubramanian, Lorenzo Tomassoni, Ester Calvo Fernández, Patrick McCann, Meri Rogava, Angelo M. De Marzo, Christina M. Kochel, Mohamad E. Allaf, Trinity J. Bivalacqua, Michael Lim, Ronald Realubit, Charles Karan, Charles G. Drake, Andrea Califano

    Published 2023
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  17. 17
    Metabolic Reprogramming of Tumor-Associated Macrophages Using Glutamine Antagonist JHU083 Drives Tumor Immunity in Myeloid-Rich Prostate and Bladder Cancers

    Metabolic Reprogramming of Tumor-Associated Macrophages Using Glutamine Antagonist JHU083 Drives Tumor Immunity in Myeloid-Rich Prostate and Bladder Cancers by Monali Praharaj, Fan Shen, Alex J. Lee, Liang Zhao, Thomas R. Nirschl, Debebe Theodros, Alok Kumar Singh, Xiaoxu Wang, Kenneth M. Adusei, Kara A. Lombardo, Raekwon A. Williams, Laura A. Sena, Elizabeth A. Thompson, Ada Tam, Srinivasan Yegnasubramanian, Edward J. Pearce, Robert D. Leone, Jesse Alt, Rana Rais, Barbara S. Slusher, Drew M. Pardoll, Jonathan D. Powell, Jelani C. Zarif

    Published 2024
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  18. 18
    Ipilimumab plus nivolumab and DNA-repair defects in AR-V7-expressing metastatic prostate cancer

    Ipilimumab plus nivolumab and DNA-repair defects in AR-V7-expressing metastatic prostate cancer by Karim Boudadi, Daniel L. Suzman, Valsamo Anagnostou, Wei Fu, Brandon Luber, Hao Wang, Noushin Niknafs, James R. White, John L. Silberstein, Rana Sullivan, Donna Dowling, Rana Harb, Thomas R. Nirschl, Brendan Veeneman, Scott A. Tomlins, Yipeng Wang, Adam Jendrisak, Ryon P. Graf, Ryan Dittamore, Michael A. Carducci, Mario A. Eisenberger, Michael C. Haffner, Alan K. Meeker, James R. Eshleman, Jun Luo, Victor E. Velculescu, Charles G. Drake, Emmanuel S. Antonarakis

    Published 2018
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