检索结果 - Thomas Eißing

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  1. 1
    A Computational Systems Biology Software Platform for Multiscale Modeling and Simulation: Integrating Whole-Body Physiology, Disease Biology, and Molecular Reaction Networks

    A Computational Systems Biology Software Platform for Multiscale Modeling and Simulation: Integrating Whole-Body Physiology, Disease Biology, and Molecular Reaction Networks 由 Thomas Eißing

    出版 2011
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  2. 2
    Applied Concepts in PBPK Modeling: How to Extend an Open Systems Pharmacology Model to the Special Population of Pregnant Women

    Applied Concepts in PBPK Modeling: How to Extend an Open Systems Pharmacology Model to the Special Population of Pregnant Women 由 André Dallmann, Juri Solodenko, Ibrahim Ince, Thomas Eißing

    出版 2018
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  3. 3
    First dose in children: physiological insights into pharmacokinetic scaling approaches and their implications in paediatric drug development

    First dose in children: physiological insights into pharmacokinetic scaling approaches and their implications in paediatric drug development 由 Ashley Strougo, Thomas Eißing, Ashraf Yassen, Stefan Willmann, Meindert Danhof, Jan Freijer

    出版 2012
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  4. 4
    Bistability Analyses of a Caspase Activation Model for Receptor-induced Apoptosis

    Bistability Analyses of a Caspase Activation Model for Receptor-induced Apoptosis 由 Thomas Eißing, H. Conzelmann, Ernst Dieter Gilles, Frank Allgöwer, Eric Bullinger, Peter Scheurich

    出版 2004
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  5. 5
    PBPK Models for CYP3A4 and P‐gp DDI Prediction: A Modeling Network of Rifampicin, Itraconazole, Clarithromycin, Midazolam, Alfentanil, and Digoxin

    PBPK Models for CYP3A4 and P‐gp DDI Prediction: A Modeling Network of Rifampicin, Itraconazole, Clarithromycin, Midazolam, Alfentanil, and Digoxin 由 Nina Hanke, Sebastian Frechen, Daniel Moj, Hannah Britz, Thomas Eißing, Thomas Wendl, Thorsten Lehr

    出版 2018
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  6. 6
    A Generic Integrated Physiologically based Whole‐body Model of the Glucose‐Insulin‐Glucagon Regulatory System

    A Generic Integrated Physiologically based Whole‐body Model of the Glucose‐Insulin‐Glucagon Regulatory System 由 Stephan Schaller, Stefan Willmann, Jörg Lippert, L. Schaupp, Thomas R. Pieber, Andreas Schuppert, Thomas Eißing

    出版 2013
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  7. 7
    Development of a Whole-Body Physiologically Based Pharmacokinetic Approach to Assess the Pharmacokinetics of Drugs in Elderly Individuals

    Development of a Whole-Body Physiologically Based Pharmacokinetic Approach to Assess the Pharmacokinetics of Drugs in Elderly Individuals 由 Jan‐Frederik Schlender, Michaela Meyer, Kirstin Thelen, Markus Krauß, Stefan Willmann, Thomas Eißing, Ulrich Jaehde

    出版 2016
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  8. 8
    Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug–Drug–Gene Interactions: A Modeling Network of Gemfibrozil, Repaglinide, Pioglitazone, Rifampicin, Clarithromycin and Itraconazole

    Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug–Drug–Gene Interactions: A Modeling Network of Gemfibrozil, Repaglinide, Pio... 由 Denise Türk, Nina Hanke, Sarah Wolf, Sebastian Frechen, Thomas Eißing, Thomas Wendl, Matthias Schwab, Thorsten Lehr

    出版 2019
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  9. 9
    Physiologically Based Pharmacokinetic Modeling of Monoclonal Antibodies in Pediatric Populations Using PK-Sim

    Physiologically Based Pharmacokinetic Modeling of Monoclonal Antibodies in Pediatric Populations Using PK-Sim 由 Sumit Basu, Yi Ting Lien, Valvanera Vozmediano, Jan‐Frederik Schlender, Thomas Eißing, Stephan Schmidt, Christoph Niederalt

    出版 2020
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  10. 10
    A generic whole body physiologically based pharmacokinetic model for therapeutic proteins in PK-Sim

    A generic whole body physiologically based pharmacokinetic model for therapeutic proteins in PK-Sim 由 Christoph Niederalt, Lars Kuepfer, Juri Solodenko, Thomas Eißing, Hans‐Ulrich Siegmund, Michael S. Block, Stefan Willmann, Jörg Lippert

    出版 2017
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  11. 11
    Applied Concepts in PBPK Modeling: How to Build a PBPK/PD Model

    Applied Concepts in PBPK Modeling: How to Build a PBPK/PD Model 由 Lars Kuepfer, Christoph Niederalt, Thomas Wendl, J‐F Schlender, Stefan Willmann, Jörg Lippert, Michael S. Block, Thomas Eißing, Donato Teutonico

    出版 2016
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  12. 12
    NT‐proBNP Qualifies as a Surrogate for Clinical End Points in Heart Failure

    NT‐proBNP Qualifies as a Surrogate for Clinical End Points in Heart Failure 由 Walter Schmitt, Hauke Rühs, Rolf Burghaus, Christian Diedrich, Sulav Duwal, Thomas Eißing, Dirk Garmann, Michaela Meyer, Bart A. Ploeger, Jörg Lippert

    出版 2021
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  13. 13
    Mechanistic Oral Absorption Modeling and Simulation for Formulation Development and Bioequivalence Evaluation: Report of an FDA Public Workshop

    Mechanistic Oral Absorption Modeling and Simulation for Formulation Development and Bioequivalence Evaluation: Report of an FDA Public Workshop 由 Xinyuan Zhang, John Duan, Filippos Kesisoglou, Jasmina Novaković, GL Amidon, Masoud Jamei, Viera Lukáčová, Thomas Eißing, Eleftheria Tsakalozou, Liang Zhao, Robert Lionberger

    出版 2017
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