Search Results - Thomas Eißing

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  1. 1
    A Computational Systems Biology Software Platform for Multiscale Modeling and Simulation: Integrating Whole-Body Physiology, Disease Biology, and Molecular Reaction Networks

    A Computational Systems Biology Software Platform for Multiscale Modeling and Simulation: Integrating Whole-Body Physiology, Disease Biology, and Molecular Reaction Networks by Thomas Eißing

    Published 2011
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  2. 2
    Applied Concepts in PBPK Modeling: How to Extend an Open Systems Pharmacology Model to the Special Population of Pregnant Women

    Applied Concepts in PBPK Modeling: How to Extend an Open Systems Pharmacology Model to the Special Population of Pregnant Women by André Dallmann, Juri Solodenko, Ibrahim Ince, Thomas Eißing

    Published 2018
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  3. 3
    First dose in children: physiological insights into pharmacokinetic scaling approaches and their implications in paediatric drug development

    First dose in children: physiological insights into pharmacokinetic scaling approaches and their implications in paediatric drug development by Ashley Strougo, Thomas Eißing, Ashraf Yassen, Stefan Willmann, Meindert Danhof, Jan Freijer

    Published 2012
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  4. 4
    Bistability Analyses of a Caspase Activation Model for Receptor-induced Apoptosis

    Bistability Analyses of a Caspase Activation Model for Receptor-induced Apoptosis by Thomas Eißing, H. Conzelmann, Ernst Dieter Gilles, Frank Allgöwer, Eric Bullinger, Peter Scheurich

    Published 2004
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  5. 5
    PBPK Models for CYP3A4 and P‐gp DDI Prediction: A Modeling Network of Rifampicin, Itraconazole, Clarithromycin, Midazolam, Alfentanil, and Digoxin

    PBPK Models for CYP3A4 and P‐gp DDI Prediction: A Modeling Network of Rifampicin, Itraconazole, Clarithromycin, Midazolam, Alfentanil, and Digoxin by Nina Hanke, Sebastian Frechen, Daniel Moj, Hannah Britz, Thomas Eißing, Thomas Wendl, Thorsten Lehr

    Published 2018
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  6. 6
    A Generic Integrated Physiologically based Whole‐body Model of the Glucose‐Insulin‐Glucagon Regulatory System

    A Generic Integrated Physiologically based Whole‐body Model of the Glucose‐Insulin‐Glucagon Regulatory System by Stephan Schaller, Stefan Willmann, Jörg Lippert, L. Schaupp, Thomas R. Pieber, Andreas Schuppert, Thomas Eißing

    Published 2013
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  7. 7
    Development of a Whole-Body Physiologically Based Pharmacokinetic Approach to Assess the Pharmacokinetics of Drugs in Elderly Individuals

    Development of a Whole-Body Physiologically Based Pharmacokinetic Approach to Assess the Pharmacokinetics of Drugs in Elderly Individuals by Jan‐Frederik Schlender, Michaela Meyer, Kirstin Thelen, Markus Krauß, Stefan Willmann, Thomas Eißing, Ulrich Jaehde

    Published 2016
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  8. 8
    Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug–Drug–Gene Interactions: A Modeling Network of Gemfibrozil, Repaglinide, Pioglitazone, Rifampicin, Clarithromycin and Itraconazole

    Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug–Drug–Gene Interactions: A Modeling Network of Gemfibrozil, Repaglinide, Pio... by Denise Türk, Nina Hanke, Sarah Wolf, Sebastian Frechen, Thomas Eißing, Thomas Wendl, Matthias Schwab, Thorsten Lehr

    Published 2019
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  9. 9
    Physiologically Based Pharmacokinetic Modeling of Monoclonal Antibodies in Pediatric Populations Using PK-Sim

    Physiologically Based Pharmacokinetic Modeling of Monoclonal Antibodies in Pediatric Populations Using PK-Sim by Sumit Basu, Yi Ting Lien, Valvanera Vozmediano, Jan‐Frederik Schlender, Thomas Eißing, Stephan Schmidt, Christoph Niederalt

    Published 2020
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  10. 10
    A generic whole body physiologically based pharmacokinetic model for therapeutic proteins in PK-Sim

    A generic whole body physiologically based pharmacokinetic model for therapeutic proteins in PK-Sim by Christoph Niederalt, Lars Kuepfer, Juri Solodenko, Thomas Eißing, Hans‐Ulrich Siegmund, Michael S. Block, Stefan Willmann, Jörg Lippert

    Published 2017
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  11. 11
    Applied Concepts in PBPK Modeling: How to Build a PBPK/PD Model

    Applied Concepts in PBPK Modeling: How to Build a PBPK/PD Model by Lars Kuepfer, Christoph Niederalt, Thomas Wendl, J‐F Schlender, Stefan Willmann, Jörg Lippert, Michael S. Block, Thomas Eißing, Donato Teutonico

    Published 2016
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  12. 12
    NT‐proBNP Qualifies as a Surrogate for Clinical End Points in Heart Failure

    NT‐proBNP Qualifies as a Surrogate for Clinical End Points in Heart Failure by Walter Schmitt, Hauke Rühs, Rolf Burghaus, Christian Diedrich, Sulav Duwal, Thomas Eißing, Dirk Garmann, Michaela Meyer, Bart A. Ploeger, Jörg Lippert

    Published 2021
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  13. 13
    Mechanistic Oral Absorption Modeling and Simulation for Formulation Development and Bioequivalence Evaluation: Report of an FDA Public Workshop

    Mechanistic Oral Absorption Modeling and Simulation for Formulation Development and Bioequivalence Evaluation: Report of an FDA Public Workshop by Xinyuan Zhang, John Duan, Filippos Kesisoglou, Jasmina Novaković, GL Amidon, Masoud Jamei, Viera Lukáčová, Thomas Eißing, Eleftheria Tsakalozou, Liang Zhao, Robert Lionberger

    Published 2017
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