Søgeresultater - Thacker, Stetson

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  1. 1
    Transcriptome-(phospho)proteome characterization of brain of a germline model of cytoplasmic-predominant Pten expression with autism-like phenotypes

    Transcriptome-(phospho)proteome characterization of brain of a germline model of cytoplasmic-predominant Pten expression with autism-like phenotypes af Thacker, Stetson, Eng, Charis

    Udgivet 2021
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  2. 2
    Alternative splicing landscape of the neural transcriptome in a cytoplasmic-predominant Pten expression murine model of autism-like Behavior

    Alternative splicing landscape of the neural transcriptome in a cytoplasmic-predominant Pten expression murine model of autism-like Behavior af Thacker, Stetson, Sefyi, Marilyn, Eng, Charis

    Udgivet 2020
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  3. 3
    Germline nuclear-predominant Pten murine model exhibits impaired social and perseverative behavior, microglial activation, and increased oxytocinergic activity

    Germline nuclear-predominant Pten murine model exhibits impaired social and perseverative behavior, microglial activation, and increased oxytocinergic activity af Sarn, Nick, Thacker, Stetson, Lee, Hyunpil, Eng, Charis

    Udgivet 2021
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  4. 4
    Dynamics and Structural Stability Effects of Germline PTEN Mutations Associated with Cancer versus Autism Phenotypes

    Dynamics and Structural Stability Effects of Germline PTEN Mutations Associated with Cancer versus Autism Phenotypes af Smith, Iris Nira, Thacker, Stetson, Jaini, Ritika, Eng, Charis

    Udgivet 2018
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  5. 5
    Constitutional mislocalization of Pten drives precocious maturation in oligodendrocytes and aberrant myelination in model of autism spectrum disorder

    Constitutional mislocalization of Pten drives precocious maturation in oligodendrocytes and aberrant myelination in model of autism spectrum disorder af Lee, Hyunpil, Thacker, Stetson, Sarn, Nicholas, Dutta, Ranjan, Eng, Charis

    Udgivet 2019
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  6. 6
    Conformational Dynamics and Allosteric Regulation Landscapes of Germline PTEN Mutations Associated with Autism Compared to Those Associated with Cancer

    Conformational Dynamics and Allosteric Regulation Landscapes of Germline PTEN Mutations Associated with Autism Compared to Those Associated with Cancer af Smith, Iris Nira, Thacker, Stetson, Seyfi, Marilyn, Cheng, Feixiong, Eng, Charis

    Udgivet 2019
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  7. 7
    Cytoplasmic-predominant Pten increases microglial activation and synaptic pruning in a murine model with autism-like phenotype

    Cytoplasmic-predominant Pten increases microglial activation and synaptic pruning in a murine model with autism-like phenotype af Sarn, Nicholas, Jaini, Ritika, Thacker, Stetson, Lee, Hyunpil, Dutta, Ranjan, Eng, Charis

    Udgivet 2020
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  8. 8
    An Integrated Deep-Mutational-Scanning Approach Provides Clinical Insights on PTEN Genotype-Phenotype Relationships

    An Integrated Deep-Mutational-Scanning Approach Provides Clinical Insights on PTEN Genotype-Phenotype Relationships af Mighell, Taylor L., Thacker, Stetson, Fombonne, Eric, Eng, Charis, O’Roak, Brian J.

    Udgivet 2020
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  9. 9
    Decreased nuclear Pten in neural stem cells contributes to deficits in neuronal maturation

    Decreased nuclear Pten in neural stem cells contributes to deficits in neuronal maturation af Kang, Shin Chung, Jaini, Ritika, Hitomi, Masahiro, Lee, Hyunpil, Sarn, Nick, Thacker, Stetson, Eng, Charis

    Udgivet 2020
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  10. 10
    Limb- and tendon-specific Adamtsl2 deletion identifies a role for ADAMTSL2 in tendon growth in a mouse model for geleophysic dysplasia

    Limb- and tendon-specific Adamtsl2 deletion identifies a role for ADAMTSL2 in tendon growth in a mouse model for geleophysic dysplasia af Hubmacher, Dirk, Taye, Nandaraj, Balic, Zerina, Thacker, Stetson, Adams, Sheila M., Birk, David E., Schweitzer, Ronen, Apte, Suneel S.

    Udgivet 2019
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  11. 11
    Germline PTEN mutations are associated with a skewed peripheral immune repertoire in humans and mice

    Germline PTEN mutations are associated with a skewed peripheral immune repertoire in humans and mice af Jaini, Ritika, Loya, Matthew G, King, Alexander T, Thacker, Stetson, Sarn, Nicholas B, Yu, Qi, Stark, George R, Eng, Charis

    Udgivet 2020
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